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Q6NJJ8 (Q6NJJ8_CORDI) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Delta-aminolevulinic acid dehydratase RuleBase RU000515
EC=4.2.1.24 RuleBase RU000515
Gene names
Name:hemB EMBL CAE48907.1
Ordered Locus Names:DIP0403
OrganismCorynebacterium diphtheriae [Complete proteome] [HAMAP]
Taxonomic identifier1717 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length330 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 5-aminolevulinate = porphobilinogen + 2 H2O. RuleBase RU000515

Subunit structure

Homooctamer By similarity. RuleBase RU000515

Sequence similarities

Belongs to the ALADH family. RuleBase RU004161

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2041Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Active site2561Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Metal binding2411Magnesium By similarity PIRSR PIRSR001415-5
Binding site2141Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2251Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2821Substrate 2 By similarity PIRSR PIRSR001415-2
Binding site3211Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

Sequence LengthMass (Da)Tools
Q6NJJ8 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: AE308B9A1FC86643

FASTA33036,105
        10         20         30         40         50         60 
MNLDLIRRPR RLRSTPVMRE FVAETTLRPA DLILPMFIAD GIDKPREIES MPGVYQHTME 

        70         80         90        100        110        120 
SLIEAVREAI SVGIRCVDLF GVPLDSDKDA TGSQAWDPEG ILNRGVRALR QEFGDQVLIM 

       130        140        150        160        170        180 
ADTCLDEFTD HGHCGILTTD RFGATIVDND PTVELYQKMA VAQAEAGAHI VSPSGMMDGQ 

       190        200        210        220        230        240 
ILAIREALDA AGFHDVAIMA YSAKYASAFY GPFRDAVGSS LQGDRRAYQQ DPANLRESIL 

       250        260        270        280        290        300 
EVDLDIEEGA DFVMVKPAMP YLDVLAEVAS TSSVPVAAYQ VSGEYAMLHA AAANGWLDLD 

       310        320        330 
RVMMESLISI KRAGADQILT YFAVEAARKL

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX248355 Genomic DNA. Translation: CAE48907.1.
RefSeqNP_938784.1. NC_002935.2.

3D structure databases

HSSPHSSP built from PDB template 1B4K based on UniProtKB Q59643.
ProteinModelPortalQ6NJJ8.
SMRQ6NJJ8. Positions 6-330.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2650207.
GenomeReviewsGene locus DIP0403 in contig BX248353_GR.
KEGGcdi:DIP0403.
NMPDRfig|257309.1.peg.375.
PATRIC21481963. VBICorDip47633_0386.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG285270.
OMAGAHCVAP.
PhylomeDBQ6NJJ8.
ProtClustDBPRK09283.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR001731. Porphobilinogen_synth.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01698.
PANTHERPTHR11458. AlaD_dehydratase. 1 hit.
PfamPF00490. ALAD. 1 hit.
[Graphical view]
PIRSFPIRSF001415. Porphbilin_synth. 1 hit.
PRINTSPR00144. DALDHYDRTASE.
SMARTSM01004. ALAD. 1 hit.
[Graphical view]
PROSITEPS00169. D_ALA_DEHYDRATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6NJJ8_CORDI
AccessionPrimary (citable) accession number: Q6NJJ8
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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