Q6NJ87 (RL6_CORDI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L6

Gene names

Name:	rplF
Ordered Locus Names:	DIP0525

Organism

Corynebacterium diphtheriae [Complete proteome] [HAMAP]

Taxonomic identifier

1717 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center By similarity. HAMAP MF_01365_B
Subunit structure	Part of the 50S ribosomal subunit By similarity. HAMAP MF_01365_B
Sequence similarities	Belongs to the ribosomal protein L6P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 178	178	50S ribosomal protein L6 HAMAP MF_01365_B		PRO_0000260855

Sequences

	Sequence		Length	Mass (Da)
	Q6NJ87 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 7696DB66CC3B695B	FASTA	178	19,339
	10 20 30 40 50 60 MSRVGKAPIA IPSGVDVKID GQHVEVKGPK GTLDLTIPEP IVASIEDGQI SVVRPDDHRK 70 80 90 100 110 120 NRSLHGLSRS LVNNMVVGVT EGYTIKMEIF GVGYRVALKG KNLEFSLGYS HPVLIEAPEG 130 140 150 160 170 ITFAVDGNTK LSVSGIDKQK VGQIAAIIRR LRKDDPYKGK GIRYEGEQIR RKVGKTGK

References

[1]

"The complete genome sequence and analysis of Corynebacterium diphtheriae NCTC13129." Cerdeno-Tarraga A.-M., Efstratiou A., Dover L.G., Holden M.T.G., Pallen M.J., Bentley S.D., Besra G.S., Churcher C.M., James K.D., De Zoysa A., Chillingworth T., Cronin A., Dowd L., Feltwell T., Hamlin N., Holroyd S., Jagels K., Moule S. , Quail M.A., Rabbinowitsch E., Rutherford K.M., Thomson N.R., Unwin L., Whitehead S., Barrell B.G., Parkhill J. Nucleic Acids Res. 31:6516-6523(2003) [PubMed: 14602910] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700971 / NCTC 13129 / Biotype gravis.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX248355 Genomic DNA. Translation: CAE49036.1.
RefSeq	NP_938901.1. NC_002935.2.
3D structure databases
HSSP	HSSP built from PDB template 1C04 based on UniProtKB P02391.
ProteinModelPortal	Q6NJ87.
SMR	Q6NJ87. Positions 8-170.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2649680.
GenomeReviews	Gene locus DIP0525 in contig BX248353_GR.
KEGG	cdi:DIP0525.
NMPDR	fig|257309.1.peg.492.
PATRIC	21482215. VBICorDip47633_0508.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG606796.
OMA	ALINNMV.
PhylomeDB	Q6NJ87.
ProtClustDB	PRK05498.
Enzyme and pathway databases
BioCyc	CDIP257309:DIP0525-MONOMER.
Family and domain databases
HAMAP	MF_01365_B. Ribosomal_L6_B. [Tree]
InterPro	IPR000702. Ribosomal_L6. IPR020040. Ribosomal_L6_a/b-dom. IPR019906. Ribosomal_L6_bac-type. [Graphical view]
Gene3D	G3DSA:3.90.930.12. Ribosomal_L6. 2 hits.
KO	K02933.
PANTHER	PTHR11655:SF6. PTHR11655:SF6. 1 hit. PTHR11655. Ribosomal_L6. 1 hit.
Pfam	PF00347. Ribosomal_L6. 2 hits. [Graphical view]
PIRSF	PIRSF002162. Ribosomal_L6. 1 hit.
PRINTS	PR00059. RIBOSOMALL6.
SUPFAM	SSF56053. Ribosomal_L6. 2 hits.
TIGRFAMs	TIGR03654. L6_bact. 1 hit.
PROSITE	PS00525. RIBOSOMAL_L6_1. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL6_CORDI

Accession

Primary (citable) accession number: Q6NJ87

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program