Q6NJ39 (GCP_CORDI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	DIP0574

Organism

Corynebacterium diphtheriae [Complete proteome] [HAMAP]

Taxonomic identifier

1717 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	350 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 350	350	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303336

Sequences

	Sequence		Length	Mass (Da)
	Q6NJ39 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 7297E00ED119AC46	FASTA	350	36,146
	10 20 30 40 50 60 MIVLGIESSC DETGVGIIDL ADDGTMTIVG DAVASSMEQH ARFGGVVPEI ASRAHLESMI 70 80 90 100 110 120 PVMKEALAQA GVERPDAVAA TVGPGLAGAL LVGASAAKAY AAAWGVPFYG VNHLGGHVAV 130 140 150 160 170 180 ANLEGEELPH SIALLVSGGH TQILEVQAVG KPMRELGSTL DDAAGEAYDK VARLLGLGYP 190 200 210 220 230 240 GGPVVDKLAA RGNRKAIRFP RGLSRADDLR GEHRYDFSFS GVKTSVARYV ESAEREGRVI 250 260 270 280 290 300 SVEDVCASFQ EAVVDVLTSK AIMACKDTGA SVLLLGGGVA ANSRLRELAA ARCQSASIEL 310 320 330 340 350 RVPSFKLCTD NGVMIAAVAS QLIHEGAQPS GLSVGTDTSL EVEIPLVHSL

References

[1]

"The complete genome sequence and analysis of Corynebacterium diphtheriae NCTC13129." Cerdeno-Tarraga A.-M., Efstratiou A., Dover L.G., Holden M.T.G., Pallen M.J., Bentley S.D., Besra G.S., Churcher C.M., James K.D., De Zoysa A., Chillingworth T., Cronin A., Dowd L., Feltwell T., Hamlin N., Holroyd S., Jagels K., Moule S. , Quail M.A., Rabbinowitsch E., Rutherford K.M., Thomson N.R., Unwin L., Whitehead S., Barrell B.G., Parkhill J. Nucleic Acids Res. 31:6516-6523(2003) [PubMed: 14602910] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700971 / NCTC 13129 / Biotype gravis.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX248355 Genomic DNA. Translation: CAE49086.1.
RefSeq	NP_938950.1. NC_002935.2.
3D structure databases
ProteinModelPortal	Q6NJ39.
ModBase	Search...
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2648770.
GenomeReviews	Gene locus DIP0574 in contig BX248353_GR.
KEGG	cdi:DIP0574.
NMPDR	fig|257309.1.peg.541.
PATRIC	21482315. VBICorDip47633_0558.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304663.
OMA	PLYGVNH.
PhylomeDB	Q6NJ39.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	CDIP257309:DIP0574-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_CORDI

Accession

Primary (citable) accession number: Q6NJ39

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program