Q6NIJ0 (Q6NIJ0_CORDI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Citrate synthase PIRNR PIRNR001369

Gene names

Name:	gltA EMBL CAE49303.1
Ordered Locus Names:	DIP0785

Organism

Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis) [Complete proteome] [HAMAP]

Taxonomic identifier

257309 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium › Corynebacterium diphtheriae

Protein attributes

Sequence length	435 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + H2O + oxaloacetate = citrate + CoA. SAAS SAAS019810
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle.
Sequence similarities	Belongs to the citrate synthase family. PIRNR PIRNR001369 RuleBase RU003406

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle RuleBase RU003370
Molecular function	Acyltransferase EMBL CAE49303.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cellular carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	citrate (Si)-synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	315	1	By similarity PIRSR PIRSR001369-1
	Active site	371	1	By similarity PIRSR PIRSR001369-1

Sequences

	Sequence		Length	Mass (Da)
	Q6NIJ0 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 779911D224E29299	FASTA	435	48,801
	10 20 30 40 50 60 MKGMLVATEN KDKAVLHYPG GEYEMDIIHA TEGNDGVVLD KLLSQTGMVT FDPGYVSTGS 70 80 90 100 110 120 TESKITYIDG DNGILRHRGY DIADLAENAT FNEVSYLLIK GHLPTVDELH KFNNEIRHHT 130 140 150 160 170 180 LLDEDFKSQF NIFPRDAHPM SVLASSVNIL STYYQDQLNP LDEEQLDKAT VRLLAKVPML 190 200 210 220 230 240 AAYAYRASKG APYMYPDNSL NARENFLRMM FGYPTEPYEV DPVVAKALDK LLILHADHEQ 250 260 270 280 290 300 NCSTSTVRMI GSAQANMFVA VAGGINALSG PLHGGANQAV LEMLEEIKAN GGDATDFMNR 310 320 330 340 350 360 VKNKEKGVRL MGFGHRVYKN YDPRAAIVKE TAHEILEHLG GDELLDLAMK LEEIALSDDY 370 380 390 400 410 420 FVSRKLYPNV DFYTGLIYRA MGFPTDFFTV LFAIGRLPGW IAQYREQLAT TTKINRPRQI 430 YTGETLRKVT PREQR

References

[1]

"The complete genome sequence and analysis of Corynebacterium diphtheriae NCTC13129." Cerdeno-Tarraga A.-M., Efstratiou A., Dover L.G., Holden M.T.G., Pallen M.J., Bentley S.D., Besra G.S., Churcher C.M., James K.D., De Zoysa A., Chillingworth T., Cronin A., Dowd L., Feltwell T., Hamlin N., Holroyd S., Jagels K., Moule S. , Quail M.A., Rabbinowitsch E., Rutherford K.M., Thomson N.R., Unwin L., Whitehead S., Barrell B.G., Parkhill J. Nucleic Acids Res. 31:6516-6523(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700971 / NCTC 13129 / Biotype gravis.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX248356 Genomic DNA. Translation: CAE49303.1.
3D structure databases
ProteinModelPortal	Q6NIJ0.
SMR	Q6NIJ0. Positions 13-435.
ModBase	Search...
Protein-protein interaction databases
STRING	257309.DIP0785.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAE49303; CAE49303; DIP0785.
PATRIC	21482755. VBICorDip47633_0774.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000021224.
OMA	PGFMATG.
ProtClustDB	PRK05614.
Enzyme and pathway databases
UniPathway	UPA00223.
Family and domain databases
Gene3D	1.10.230.10. 1 hit. 1.10.580.10. 1 hit.
InterPro	IPR016142. Citrate_synth-like_lrg_a-sub. IPR016143. Citrate_synth-like_sm_a-sub. IPR002020. Citrate_synthase-like. IPR016141. Citrate_synthase-like_core. IPR019810. Citrate_synthase_AS. IPR024176. Citrate_synthase_bac-typ. IPR010953. Citrate_synthase_typ-II. [Graphical view]
PANTHER	PTHR11739. PTHR11739. 1 hit.
Pfam	PF00285. Citrate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001369. Citrate_synth. 1 hit.
PRINTS	PR00143. CITRTSNTHASE.
SUPFAM	SSF48256. Citrate_synthase_core. 1 hit.
TIGRFAMs	TIGR01798. cit_synth_I. 1 hit.
PROSITE	PS00480. CITRATE_SYNTHASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6NIJ0_CORDI

Accession

Primary (citable) accession number: Q6NIJ0

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	May 29, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)