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Q6NIE5

- G6PI_CORDI

UniProt

Q6NIE5 - G6PI_CORDI

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei355 – 3551Proton donorUniRule annotation
    Active sitei386 – 3861UniRule annotation
    Active sitei512 – 5121UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:DIP0832
    OrganismiCorynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
    Taxonomic identifieri257309 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
    ProteomesiUP000002198: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 547547Glucose-6-phosphate isomerasePRO_0000180631Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi257309.DIP0832.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6NIE5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000261371.
    KOiK01810.
    OMAiGVESYKR.
    OrthoDBiEOG64R61J.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6NIE5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSFDVTTTEP WATLSERYTA MKATTLRDLF ASNPNRAQEL SFEAAGLHVD    50
    LSKNLIDAET VAAFTALAKA SGMREKIKAM FDGEHINNTE DRAVLHTALR 100
    LAVDAELNVD GQDVAADVHE VLGRMRDFAT SLRNGSWRGY SNHTIKTIVN 150
    IGIGGSDLGP AMATKALRTY ATAGINAKFV SNVDPADMHA VLDELDPEST 200
    LFVVASKTFT TQETLANAHA AKRWLVAAAG GDESAVAKHF VAVSTNAEKV 250
    AEFGIDTKNM FGFWNWVGGR YSVDSAIGLS LMSVIGPMDF MRFLDGFRAM 300
    DEHFRTADFE SNIPVLMGML NVFYNDFFGA ETHAVLPYSQ DLGRFPAYLQ 350
    QLTMESNGKS VRHDGSAVTT NTGEIYWGEP GTNGQHAFFQ LIHQGTKLIP 400
    ADFIGFARPK EDLPTASGEG SMHDLLMSNF FAQTKVLAFG KTAEEIAAEG 450
    VSPELVAHKV MPGNRPTTTI MAEELTPFAL GALIALYEHI VFVEGVIWDI 500
    NSFDQWGVEL GKQQANDLAP AVAGEVAVDS GDSSTDALIS WYRSHRG 547
    Length:547
    Mass (Da):59,411
    Last modified:July 5, 2004 - v1
    Checksum:i23FF0EEF84F3B559
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX248356 Genomic DNA. Translation: CAE49348.1.
    RefSeqiNP_939196.1. NC_002935.2.
    WP_010934598.1. NC_002935.2.

    Genome annotation databases

    EnsemblBacteriaiCAE49348; CAE49348; DIP0832.
    GeneIDi2649294.
    KEGGicdi:DIP0832.
    PATRICi21482833. VBICorDip47633_0812.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX248356 Genomic DNA. Translation: CAE49348.1 .
    RefSeqi NP_939196.1. NC_002935.2.
    WP_010934598.1. NC_002935.2.

    3D structure databases

    ProteinModelPortali Q6NIE5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 257309.DIP0832.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAE49348 ; CAE49348 ; DIP0832 .
    GeneIDi 2649294.
    KEGGi cdi:DIP0832.
    PATRICi 21482833. VBICorDip47633_0812.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000261371.
    KOi K01810.
    OMAi GVESYKR.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700971 / NCTC 13129 / Biotype gravis.

    Entry informationi

    Entry nameiG6PI_CORDI
    AccessioniPrimary (citable) accession number: Q6NIE5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 29, 2005
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3