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Q6NHR6 (GLGB_CORDI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-alpha-glucan branching enzyme GlgB

EC=2.4.1.18
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE
Gene names
Name:glgB
Ordered Locus Names:DIP1065
OrganismCorynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis) [Complete proteome] [HAMAP]
Taxonomic identifier257309 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length732 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP-Rule MF_00685

Catalytic activity

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP-Rule MF_00685

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00685

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00685

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7327321,4-alpha-glucan branching enzyme GlgB HAMAP-Rule MF_00685
PRO_0000188697

Sites

Active site4091Nucleophile By similarity
Active site4621Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6NHR6 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 6A734BCBFC3B0441

FASTA73282,603
        10         20         30         40         50         60 
MVSPTQITPV HPDVLHALKI CQYHDPHGVY GWHEVDAERA VIRTRHIGAE RVETLLSDST 

        70         80         90        100        110        120 
VVELAAVGDD IFEAIVDHDA SCDYRLRIHW QGGQVTEQAD AYHFLPTLGD LDLHLINEGR 

       130        140        150        160        170        180 
HERLWEVLGA NPTTITTAMG DVEGTAFAVW APNASGVAVI GDFCGWNPSQ YPMRSLGSTG 

       190        200        210        220        230        240 
IWELFIPNIG VGTVYKFAIH THEGHRLDKA DPMAKRAEVA PATGSIIASS SYTWNDDTWM 

       250        260        270        280        290        300 
TNRAHTDHDN TAMSVYEVHL GSWSQGQNYE ELATNLVDYV KEMGYTHVEF LPVAEHPFGG 

       310        320        330        340        350        360 
SWGYQVSGYY APTSRWGTPD QLRLLIDAFH QAGIGVIVDW VPAHFPKDAF ALGRFDGQAL 

       370        380        390        400        410        420 
YEHPDWRRGE QKDWGTYVFD FGRNEVRNFL VANALYWLEE FHVDGLRVDA VASMLYLDYS 

       430        440        450        460        470        480 
REPGEWLPNI YGGRENLEAV QFLQEMNATV HKSHPGVMTI AEESTSWPGV TSPTWEGGLG 

       490        500        510        520        530        540 
FSMKWNMGWM NDTLEYFSHE PIHRMYHHND ITFSMVYAYS EKFVLPFSHD EVVHGKGSLW 

       550        560        570        580        590        600 
TRMPGDAWNK AAGLRTLYAY MYAHPGKNLL FQGQEFGQVK EWSEERSLDW GDMDGWEGEY 

       610        620        630        640        650        660 
HRGIRTLVQD LNALYKDSPA LYSQDNNPAG FSWTKSDDAA NNILSFVRYG ADGSKILAVF 

       670        680        690        700        710        720 
NFGGADHPSY KLGVPEGGNW KCILNTDAGI YEGEDNYLDS DVMAWDTDWD GYQHSLTVHI 

       730 
PAMSGQLYRW EA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX248357 Genomic DNA. Translation: CAE49588.1.
RefSeqNP_939426.1. NC_002935.2.

3D structure databases

ProteinModelPortalQ6NHR6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257309.DIP1065.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE49588; CAE49588; DIP1065.
GeneID2649325.
KEGGcdi:DIP1065.
PATRIC21483311. VBICorDip47633_1048.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
HOGENOMHOG000283037.
KOK00700.
OMAISEGRHE.
OrthoDBEOG6JX7GT.

Enzyme and pathway databases

UniPathwayUPA00164.

Family and domain databases

Gene3D2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_00685. GlgB.
InterProIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 2 hits.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFPIRSF000463. GlgB. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsTIGR01515. branching_enzym. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGB_CORDI
AccessionPrimary (citable) accession number: Q6NHR6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: July 5, 2004
Last modified: June 11, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries