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Q6NHP3 (Q6NHP3_CORDI) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphofructokinase HAMAP-Rule MF_00339

Short name=Phosphofructokinase HAMAP-Rule MF_00339
EC=2.7.1.11 HAMAP-Rule MF_00339
Alternative name(s):
Phosphohexokinase HAMAP-Rule MF_00339
Gene names
Name:pfkA HAMAP-Rule MF_00339 EMBL CAE49611.1
Ordered Locus Names:DIP1088 EMBL CAE49611.1
OrganismCorynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis) [Complete proteome] [HAMAP]
Taxonomic identifier257309 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length342 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate. HAMAP-Rule MF_00339

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4. HAMAP-Rule MF_00339

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00339.

Sequence similarities

Belongs to the phosphofructokinase family. HAMAP-Rule MF_00339

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding20 – 245ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding154 – 1585ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding171 – 18717ATP By similarity HAMAP-Rule MF_00339

Sites

Active site1271Proton acceptor By similarity HAMAP-Rule MF_00339
Binding site1621Substrate By similarity HAMAP-Rule MF_00339
Binding site2661Substrate By similarity HAMAP-Rule MF_00339
Binding site2721Substrate By similarity HAMAP-Rule MF_00339
Binding site2751Substrate By similarity HAMAP-Rule MF_00339

Sequences

Sequence LengthMass (Da)Tools
Q6NHP3 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: E30976C612ACF54B

FASTA34236,978
        10         20         30         40         50         60 
MRIATLTSGG DCPGLNAVIR GIVRTCSEYG STVVGYQDGW VGLMEDKRIQ LYDDENIDRI 

        70         80         90        100        110        120 
LLRGGTILGT GRLHPDKFKS GLDQIKANLE DAGIDALIPI GGEGTLKGAK WLSDNGIPVV 

       130        140        150        160        170        180 
GVPKTIDNDV NGTDYTFGFD TAVSVATDAI DRLHTTAESH NRVMIVEVMG RHVGWIALHA 

       190        200        210        220        230        240 
GMAGGAHYTV IPEQPFDIAE ICKAMERRFQ MGEKYGIIVV AEGALPKEGT MDFVEGGVDQ 

       250        260        270        280        290        300 
FGHQTFNGIG QVIGEEIKKR LGHDVRTTVL GHIQRGGTPT SYDRVLATRY GVHAARACHN 

       310        320        330        340 
GDYGKMVALH GEHIDLIPLE DAVDTLKTVP EGRYRTARAL FG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX248357 Genomic DNA. Translation: CAE49611.1.
RefSeqNP_939449.1. NC_002935.2.

3D structure databases

ProteinModelPortalQ6NHP3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257309.DIP1088.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE49611; CAE49611; DIP1088.
GeneID2649348.
KEGGcdi:DIP1088.
PATRIC21483359. VBICorDip47633_1072.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000248869.
KOK00850.
OMAWVGLMED.
OrthoDBEOG644ZRM.
ProtClustDBPRK03202.

Enzyme and pathway databases

UniPathwayUPA00109; UER00182.

Family and domain databases

HAMAPMF_00339. Phosphofructokinase.
InterProIPR012003. ATP_PFK_prok.
IPR012829. PFK.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PIRSFPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. SSF53784. 1 hit.
TIGRFAMsTIGR02483. PFK_mixed. 1 hit.
PROSITEPS00433. PHOSPHOFRUCTOKINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6NHP3_CORDI
AccessionPrimary (citable) accession number: Q6NHP3
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)