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Q6NH14 (Q6NH14_CORDI) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydroorotase RuleBase RU003441
EC=3.5.2.3 RuleBase RU003441
Gene names
Name:pyrC EMBL CAE49861.1
Ordered Locus Names:DIP1333
OrganismCorynebacterium diphtheriae [Complete proteome] [HAMAP]
Taxonomic identifier1717 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length448 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate. RuleBase RU003441 SAAS SAAS002195

Cofactor

Binds 2 zinc ions per subunit By similarity. RuleBase RU003441 SAAS SAAS002195

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3. RuleBase RU003441 SAAS SAAS002195

Subunit structure

Homodimer By similarity. SAAS SAAS002195

Sequence similarities

Belongs to the DHOase family. Type 2 subfamily. RuleBase RU003441

Sequences

Sequence LengthMass (Da)Tools
Q6NH14 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 4BB50D9C6AF732CE

FASTA44848,051
        10         20         30         40         50         60 
MSTQNYPATG RLAEPEYGTL LVKNVKIYGE GEPVNVLITD GVITDTHAGD VKADREVDGQ 

        70         80         90        100        110        120 
GGVLLPGLVD IHVHLREPGR EDTETIATGS AAAAKGGFTA VFTMANTMPV MDQPIIAESV 

       130        140        150        160        170        180 
WHKGQDIGLC DVHPVGSITK GLEGKEITEF GMMAHSQAKV RMFSDDGKCV DNPLIMRRAV 

       190        200        210        220        230        240 
EYARGTDVLL AQHCEDPRLT DGAVAHEGAM AAKLGLGGWP RVAEESIVAR DAILARDYGG 

       250        260        270        280        290        300 
RMHICHASTQ GTVELVKWAK EHEIPLTAEV TPHHLLLTDE RLATYDGVNR VNPPLRENSD 

       310        320        330        340        350        360 
ILALRDALLN GTIDCVATDH APHGSEDKCC EFEHAKPGML GLETSLAVVA AVFVETGLAD 

       370        380        390        400        410        420 
WRFVAKVMSE RPAEIVKLPG HGRPIAVGEP ANLTIVDPGA KWTASGEKMA SKATNTPYEG 

       430        440 
MEFNARVTTT ILRGRLTCVD GEPTQARA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX248357 Genomic DNA. Translation: CAE49861.1.
RefSeqNP_939686.1. NC_002935.2.

3D structure databases

ProteinModelPortalQ6NH14.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2649887.
GenomeReviewsGene locus DIP1333 in contig BX248353_GR.
KEGGcdi:DIP1333.
NMPDRfig|257309.1.peg.1277.
PATRIC21483860. VBICorDip47633_1313.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG724623.
OMACDVHPVG.
PhylomeDBQ6NH14.
ProtClustDBPRK09357.

Family and domain databases

HAMAPMF_00220_B. PyrC_type2_B.
[Tree]
InterProIPR006680. Amidohydro_1.
IPR004722. DHOase.
IPR002195. Dihydroorotase_CS.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
KOK01465.
PfamPF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMSSF51338. Metalo_hydrolase. 1 hit.
TIGRFAMsTIGR00857. PyrC_multi. 1 hit.
PROSITEPS00482. DIHYDROOROTASE_1. 1 hit.
PS00483. DIHYDROOROTASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6NH14_CORDI
AccessionPrimary (citable) accession number: Q6NH14
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: December 14, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info