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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei136 – 1361GTPUniRule annotation
Binding sitei140 – 1401GTPUniRule annotation
Binding sitei184 – 1841GTPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi18 – 225GTPUniRule annotation
Nucleotide bindingi105 – 1073GTPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, SeptationUniRule annotation

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:DIP1595Imported
OrganismiCorynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)Imported
Taxonomic identifieri257309 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
Proteomesi
  • UP000002198 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiQ6NGD1.

Structurei

3D structure databases

ProteinModelPortaliQ6NGD1.
SMRiQ6NGD1. Positions 22-312.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 202193TubulinInterPro annotationAdd
BLAST
Domaini204 – 321118Tubulin_CInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000049094.
KOiK03531.
OMAiIWGTSVD.

Family and domain databases

Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiIPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiPS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6NGD1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSPDNYLAV IKVVGVGGGG VNAVNRMIEE GLKGVEFIAV NTDSQALMFS
60 70 80 90 100
DADVKLDIGR EATRGLGAGA NPEVGRASAE DHKNEIEETL KGADMVFVTA
110 120 130 140 150
GEGGGTGTGA APVVAGIAKR LGALTVGVVT RPFKFEGPRR TRQAMEGIDA
160 170 180 190 200
LREVCDTLIV IPNDRLLQLG DANITMVDAF HEADRVLHNG VQGITDLITI
210 220 230 240 250
PGLINVDFAD VRSVMHDAGS ALMGVGSASG ENRVLTAAEQ AINSPLLEST
260 270 280 290 300
MEGAKGVLLS VAGGSDLGLQ EVNEAASMVQ EKADEDVNLI FGTIFDDNLG
310 320 330 340 350
DEVRITVIAT GFDGEKNSLD RQREAAQPAA SQSASAMEAN PTPAPDRSTS
360 370 380 390 400
TSLFGDSDSA PRHRLNEEPA ARRTSHDSEG MYTRRSVPRE SYRDQRSDDF
410
DDDLDIPDFL R
Length:411
Mass (Da):43,466
Last modified:July 5, 2004 - v1
Checksum:i033FB86EB27BFD64
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248358 Genomic DNA. Translation: CAE50120.1.
RefSeqiWP_010935182.1. NC_002935.2.

Genome annotation databases

EnsemblBacteriaiCAE50120; CAE50120; DIP1595.
GeneIDi2650784.
KEGGicdi:DIP1595.
PATRICi21484398. VBICorDip47633_1575.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX248358 Genomic DNA. Translation: CAE50120.1.
RefSeqiWP_010935182.1. NC_002935.2.

3D structure databases

ProteinModelPortaliQ6NGD1.
SMRiQ6NGD1. Positions 22-312.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ6NGD1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAE50120; CAE50120; DIP1595.
GeneIDi2650784.
KEGGicdi:DIP1595.
PATRICi21484398. VBICorDip47633_1575.

Phylogenomic databases

HOGENOMiHOG000049094.
KOiK03531.
OMAiIWGTSVD.

Family and domain databases

Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiIPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiPS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6NGD1_CORDI
AccessioniPrimary (citable) accession number: Q6NGD1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.