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Q6NGA0

- COX3_CORDI

UniProt

Q6NGA0 - COX3_CORDI

Protein

Cytochrome c oxidase subunit 3

Gene

ctaE

Organism
Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. aerobic electron transport chain Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome aa3 subunit 3
    Cytochrome c oxidase polypeptide III
    Gene namesi
    Name:ctaE
    Ordered Locus Names:DIP1627
    OrganismiCorynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
    Taxonomic identifieri257309 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
    ProteomesiUP000002198: Chromosome

    Subcellular locationi

    Cell membrane By similarity; Multi-pass membrane protein By similarity

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 205205Cytochrome c oxidase subunit 3PRO_0000183878Add
    BLAST

    Interactioni

    Subunit structurei

    Associates with subunits I, II and IV to form cytochrome c oxidase.By similarity

    Protein-protein interaction databases

    STRINGi257309.DIP1627.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6NGA0.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei28 – 4821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei72 – 9221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei104 – 12421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei142 – 16221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei184 – 20421HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1845.
    HOGENOMiHOG000086399.
    KOiK02276.
    OMAiFAFINTI.
    OrthoDBiEOG6SFPBZ.

    Family and domain databases

    Gene3Di1.20.120.80. 1 hit.
    InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view]
    PANTHERiPTHR11403. PTHR11403. 1 hit.
    PfamiPF00510. COX3. 1 hit.
    [Graphical view]
    SUPFAMiSSF81452. SSF81452. 1 hit.
    PROSITEiPS50253. COX3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6NGA0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTSAIGNKDM AAPQRVAALN RPNMVSVGTI VFLSQELMFF AGLFAMYFTS    50
    RANGIGNGSW KEGAHHLNVP YALVITIILI SSSVTAQFGV FAAERGDVFG 100
    VRRWFSLTIL LGAIFLVGQA YEYFHLVEHG MTIQSSVYGS SFFITTGFHA 150
    AHVLAGALAF VVVLLRLSKS KFTPAQATAA MVVSYYWHFV DVVWIGLFIT 200
    IYFIQ 205
    Length:205
    Mass (Da):22,507
    Last modified:July 5, 2004 - v1
    Checksum:iA401B97D0B9740AA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX248358 Genomic DNA. Translation: CAE50152.1.
    RefSeqiNP_939969.1. NC_002935.2.
    WP_010935207.1. NC_002935.2.

    Genome annotation databases

    EnsemblBacteriaiCAE50152; CAE50152; DIP1627.
    GeneIDi2648673.
    KEGGicdi:DIP1627.
    PATRICi21484462. VBICorDip47633_1607.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX248358 Genomic DNA. Translation: CAE50152.1 .
    RefSeqi NP_939969.1. NC_002935.2.
    WP_010935207.1. NC_002935.2.

    3D structure databases

    ProteinModelPortali Q6NGA0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 257309.DIP1627.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAE50152 ; CAE50152 ; DIP1627 .
    GeneIDi 2648673.
    KEGGi cdi:DIP1627.
    PATRICi 21484462. VBICorDip47633_1607.

    Phylogenomic databases

    eggNOGi COG1845.
    HOGENOMi HOG000086399.
    KOi K02276.
    OMAi FAFINTI.
    OrthoDBi EOG6SFPBZ.

    Family and domain databases

    Gene3Di 1.20.120.80. 1 hit.
    InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view ]
    PANTHERi PTHR11403. PTHR11403. 1 hit.
    Pfami PF00510. COX3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81452. SSF81452. 1 hit.
    PROSITEi PS50253. COX3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700971 / NCTC 13129 / Biotype gravis.

    Entry informationi

    Entry nameiCOX3_CORDI
    AccessioniPrimary (citable) accession number: Q6NGA0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2005
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3