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Q6NGA0 (COX3_CORDI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Gene names
Name:ctaE
Ordered Locus Names:DIP1627
OrganismCorynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis) [Complete proteome] [HAMAP]
Taxonomic identifier257309 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length205 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subunit structure

Associates with subunits I, II and IV to form cytochrome c oxidase By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 205205Cytochrome c oxidase subunit 3
PRO_0000183878

Regions

Transmembrane28 – 4821Helical; Potential
Transmembrane72 – 9221Helical; Potential
Transmembrane104 – 12421Helical; Potential
Transmembrane142 – 16221Helical; Potential
Transmembrane184 – 20421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q6NGA0 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: A401B97D0B9740AA

FASTA20522,507
        10         20         30         40         50         60 
MTSAIGNKDM AAPQRVAALN RPNMVSVGTI VFLSQELMFF AGLFAMYFTS RANGIGNGSW 

        70         80         90        100        110        120 
KEGAHHLNVP YALVITIILI SSSVTAQFGV FAAERGDVFG VRRWFSLTIL LGAIFLVGQA 

       130        140        150        160        170        180 
YEYFHLVEHG MTIQSSVYGS SFFITTGFHA AHVLAGALAF VVVLLRLSKS KFTPAQATAA 

       190        200 
MVVSYYWHFV DVVWIGLFIT IYFIQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX248358 Genomic DNA. Translation: CAE50152.1.
RefSeqNP_939969.1. NC_002935.2.

3D structure databases

ProteinModelPortalQ6NGA0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257309.DIP1627.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE50152; CAE50152; DIP1627.
GeneID2648673.
KEGGcdi:DIP1627.
PATRIC21484462. VBICorDip47633_1607.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1845.
HOGENOMHOG000086399.
KOK02276.
OMAFAFINTI.
OrthoDBEOG6SFPBZ.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_CORDI
AccessionPrimary (citable) accession number: Q6NGA0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: July 5, 2004
Last modified: May 14, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families