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Q6NG99 (COX4_CORDI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase polypeptide 4

EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 4
Cytochrome c oxidase polypeptide IV
Gene names
Name:ctaF
Ordered Locus Names:DIP1628
OrganismCorynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis) [Complete proteome] [HAMAP]
Taxonomic identifier257309 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length143 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of cytochrome c oxidase, its function is unknown By similarity.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subunit structure

Associates with subunits I, II and III to form cytochrome c oxidase By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase bacterial subunit CtaF family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 143143Cytochrome c oxidase polypeptide 4
PRO_0000220013

Regions

Transmembrane7 – 2721Helical; Potential
Transmembrane40 – 6021Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane106 – 12621Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q6NG99 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 38C6FBF16A316CD0

FASTA14315,776
        10         20         30         40         50         60 
MKATSKIMYS MATFLAIMAI IYLFATMHVE DSGYMVGYEW AGGVCMILGT LLTVMLGGYL 

        70         80         90        100        110        120 
HFTENRIDVL PEDWEEAEVA DAAGTLGFFS PSSIWPLAMS GAIAVLGFGI VYMHYWLIAI 

       130        140 
GAVLLIYTTT MLNLQYGIPK EKH 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX248358 Genomic DNA. Translation: CAE50153.1.
RefSeqNP_939970.1. NC_002935.2.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257309.DIP1628.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE50153; CAE50153; DIP1628.
GeneID2648674.
KEGGcdi:DIP1628.
PATRIC21484464. VBICorDip47633_1608.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGNOG07397.
HOGENOMHOG000237887.
OMAGTYFRFV.
OrthoDBEOG63FW2X.
ProtClustDBCLSK2518736.

Family and domain databases

InterProIPR021050. Cyt_c_oxidase_su4_actinobac.
[Graphical view]
PfamPF12270. Cyt_c_ox_IV. 1 hit.
[Graphical view]
PIRSFPIRSF017385. CtaF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCOX4_CORDI
AccessionPrimary (citable) accession number: Q6NG99
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families