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Protein

DNA polymerase III subunit beta

Gene

dnaN

Organism
Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingSAAS annotation, DNA-directed DNA polymeraseUniRule annotationSAAS annotation, Nucleotidyltransferase, Transferase
Biological processDNA replicationUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase III subunit betaUniRule annotation
Gene namesi
Name:dnaNImported
Ordered Locus Names:RPA0002Imported
OrganismiRhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)Imported
Taxonomic identifieri258594 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
Proteomesi
  • UP000001426 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi258594.RPA0002.

Structurei

3D structure databases

ProteinModelPortaliQ6NDV2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 120DNA_pol3_betaInterPro annotationAdd BLAST120
Domaini131 – 249DNA_pol3_beta_2InterPro annotationAdd BLAST119
Domaini252 – 371DNA_pol3_beta_3InterPro annotationAdd BLAST120

Sequence similaritiesi

Belongs to the beta sliding clamp family.SAAS annotation

Phylogenomic databases

eggNOGiENOG4105CZ8. Bacteria.
COG0592. LUCA.
HOGENOMiHOG000071791.
KOiK02338.
OMAiNYEAVIP.
OrthoDBiPOG091H02B3.
PhylomeDBiQ6NDV2.

Family and domain databases

CDDicd00140. beta_clamp. 1 hit.
InterProiView protein in InterPro
IPR001001. DNA_polIII_beta.
IPR022635. DNA_polIII_beta_C.
IPR022637. DNA_polIII_beta_cen.
IPR022634. DNA_polIII_beta_N.
PANTHERiPTHR30478:SF1. PTHR30478:SF1. 1 hit.
PfamiView protein in Pfam
PF00712. DNA_pol3_beta. 1 hit.
PF02767. DNA_pol3_beta_2. 1 hit.
PF02768. DNA_pol3_beta_3. 1 hit.
PIRSFiPIRSF000804. DNA_pol_III_b. 1 hit.
SMARTiView protein in SMART
SM00480. POL3Bc. 1 hit.
TIGRFAMsiTIGR00663. dnan. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6NDV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVTVERAQL LKSLSHVHRV VERRNTIPIL GNVLVRAENA QLALKATDLD
60 70 80 90 100
LEVTETLPAE TATAGSTTVP AHMFYDIVRK LPDGSQIVLE SDGDRSVLAI
110 120 130 140 150
RAGRSRFTLQ TLPESDFPDL AAGEMSHAFR LPASDVKRLI DRTQFAISTE
160 170 180 190 200
ETRYYLNGIY LHTAGSPKAS SLRAVATDGH RLAQLDLTLP SGADGMPGVI
210 220 230 240 250
VPRKTVGEVQ RLIEDTEAEI GIELSTGKIR FTLGNVVLTS KLIDGTFPDY
260 270 280 290 300
GRVIPQNNDK ELLVDKKDFE AAVDRVSTIS SERGRAVKLA LSAGKLVLSV
310 320 330 340 350
TNPDSGSATE ELEVEYASDP LDIGFNSRYL LDIAAQIEGE VAVLKLADPG
360 370
SPTLIQDRDS KSALYVLMPM RV
Length:372
Mass (Da):40,401
Last modified:July 5, 2004 - v1
Checksum:iF40C763C0E1009EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX572593 Genomic DNA. Translation: CAE25446.1.
RefSeqiWP_011155573.1. NC_005296.1.

Genome annotation databases

EnsemblBacteriaiCAE25446; CAE25446; RPA0002.
KEGGirpa:RPA0002.

Similar proteinsi

Entry informationi

Entry nameiQ6NDV2_RHOPA
AccessioniPrimary (citable) accession number: Q6NDV2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 27, 2017
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported