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Protein

DNA polymerase III subunit beta

Gene

dnaN

Organism
Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.UniRule annotation

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).UniRule annotationSAAS annotation

GO - Molecular functioni

  1. 3'-5' exonuclease activity Source: InterPro
  2. DNA binding Source: InterPro
  3. DNA-directed DNA polymerase activity Source: UniProtKB-KW

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

DNA-directed DNA polymeraseUniRule annotationSAAS annotation, Nucleotidyltransferase, Transferase

Keywords - Biological processi

DNA replicationUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase III subunit betaUniRule annotationSAAS annotation (EC:2.7.7.7UniRule annotationSAAS annotation)
Gene namesi
Name:dnaNImported
Ordered Locus Names:RPA0002Imported
OrganismiRhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)Imported
Taxonomic identifieri258594 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
ProteomesiUP000001426 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. DNA polymerase III complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi258594.RPA0002.

Structurei

3D structure databases

ProteinModelPortaliQ6NDV2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000071791.
KOiK02338.
OMAiIAFNVRY.
OrthoDBiEOG65J53F.
PhylomeDBiQ6NDV2.

Family and domain databases

InterProiIPR001001. DNA_polIII_beta.
IPR022635. DNA_polIII_beta_C.
IPR022637. DNA_polIII_beta_cen.
IPR022634. DNA_polIII_beta_N.
[Graphical view]
PfamiPF00712. DNA_pol3_beta. 1 hit.
PF02767. DNA_pol3_beta_2. 1 hit.
PF02768. DNA_pol3_beta_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000804. DNA_pol_III_b. 1 hit.
SMARTiSM00480. POL3Bc. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00663. dnan. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6NDV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVTVERAQL LKSLSHVHRV VERRNTIPIL GNVLVRAENA QLALKATDLD
60 70 80 90 100
LEVTETLPAE TATAGSTTVP AHMFYDIVRK LPDGSQIVLE SDGDRSVLAI
110 120 130 140 150
RAGRSRFTLQ TLPESDFPDL AAGEMSHAFR LPASDVKRLI DRTQFAISTE
160 170 180 190 200
ETRYYLNGIY LHTAGSPKAS SLRAVATDGH RLAQLDLTLP SGADGMPGVI
210 220 230 240 250
VPRKTVGEVQ RLIEDTEAEI GIELSTGKIR FTLGNVVLTS KLIDGTFPDY
260 270 280 290 300
GRVIPQNNDK ELLVDKKDFE AAVDRVSTIS SERGRAVKLA LSAGKLVLSV
310 320 330 340 350
TNPDSGSATE ELEVEYASDP LDIGFNSRYL LDIAAQIEGE VAVLKLADPG
360 370
SPTLIQDRDS KSALYVLMPM RV
Length:372
Mass (Da):40,401
Last modified:July 5, 2004 - v1
Checksum:iF40C763C0E1009EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX572593 Genomic DNA. Translation: CAE25446.1.
RefSeqiNP_945358.1. NC_005296.1.
WP_011155573.1. NC_005296.1.

Genome annotation databases

EnsemblBacteriaiCAE25446; CAE25446; RPA0002.
KEGGirpa:RPA0002.
PATRICi23284095. VBIRhoPal84835_0002.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX572593 Genomic DNA. Translation: CAE25446.1.
RefSeqiNP_945358.1. NC_005296.1.
WP_011155573.1. NC_005296.1.

3D structure databases

ProteinModelPortaliQ6NDV2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi258594.RPA0002.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAE25446; CAE25446; RPA0002.
KEGGirpa:RPA0002.
PATRICi23284095. VBIRhoPal84835_0002.

Phylogenomic databases

HOGENOMiHOG000071791.
KOiK02338.
OMAiIAFNVRY.
OrthoDBiEOG65J53F.
PhylomeDBiQ6NDV2.

Family and domain databases

InterProiIPR001001. DNA_polIII_beta.
IPR022635. DNA_polIII_beta_C.
IPR022637. DNA_polIII_beta_cen.
IPR022634. DNA_polIII_beta_N.
[Graphical view]
PfamiPF00712. DNA_pol3_beta. 1 hit.
PF02767. DNA_pol3_beta_2. 1 hit.
PF02768. DNA_pol3_beta_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000804. DNA_pol_III_b. 1 hit.
SMARTiSM00480. POL3Bc. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00663. dnan. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-98 / CGA009Imported.

Entry informationi

Entry nameiQ6NDV2_RHOPA
AccessioniPrimary (citable) accession number: Q6NDV2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: April 1, 2015
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.