Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6ND22

- SYL_RHOPA

UniProt

Q6ND22 - SYL_RHOPA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Leucine--tRNA ligase

Gene

leuS

Organism
Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei635 – 6351ATPUniRule annotation

GO - Molecular functioni

  1. aminoacyl-tRNA editing activity Source: InterPro
  2. ATP binding Source: UniProtKB-HAMAP
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligaseUniRule annotation (EC:6.1.1.4UniRule annotation)
Alternative name(s):
Leucyl-tRNA synthetaseUniRule annotation
Short name:
LeuRSUniRule annotation
Gene namesi
Name:leuSUniRule annotation
Ordered Locus Names:RPA0287
OrganismiRhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Taxonomic identifieri258594 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
ProteomesiUP000001426: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 876876Leucine--tRNA ligasePRO_0000152073Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi258594.RPA0287.

Structurei

3D structure databases

ProteinModelPortaliQ6ND22.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi43 – 5311"HIGH" regionAdd
BLAST
Motifi632 – 6365"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200747.
KOiK01869.
OMAiPVIHCPK.
OrthoDBiEOG63Z74X.
PhylomeDBiQ6ND22.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR015413. Methionyl/Leucyl_tRNA_Synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 2 hits.
PF13603. tRNA-synt_1_2. 1 hit.
PF09334. tRNA-synt_1g. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6ND22-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSNERYNARE SEPKWQAKWD EAKIFATRND DLRKKYYVLE MFPYPSGRIH
60 70 80 90 100
MGHVRNYTMG DVVARTMRAR GYNVLHPMGW DAFGLPAENA AIERKVAPKA
110 120 130 140 150
WTYDNIAAMK KQLQTMGLSL DWAREFATCD PSYYKHQQKM FLDFLKVGLV
160 170 180 190 200
EREKRKLNWD PVDMTVLANE QVIDGRGWRS GAVVELREMN QWVFKITKYA
210 220 230 240 250
QELLDALDTL DRWPDKVRLM QRNWIGRSEG LMVRFALDSA TTPAGETELK
260 270 280 290 300
IFTTRPDTLF GAKFMAIAAD HPLAQAAAAK APKVAAFIDD CKKRGTAQAE
310 320 330 340 350
IDTAEKQGID TGIRAVHPFD PSWKLPVYVA NFVLMEYGTG AIFGCPAHDQ
360 370 380 390 400
RDLDFVNKYQ LGNTPVVCPE GQDPASFVIT DTAYDGEGRM INSRFLDGKT
410 420 430 440 450
IAEAKEEVAK RLETEQLAGA PVGARKVNFR LRDWGISRQR YWGCPIPIIH
460 470 480 490 500
CPTCDVVPVP DADLPVVLPE DVSFDKPGNA LDHHPTWKHV TCPKCGGKAV
510 520 530 540 550
RETDTMDTFV DSSWYFARFT DPWNTEAPTT PDVVNRMMPV DQYIGGVEHA
560 570 580 590 600
ILHLLYSRFF TRAMKAAGHI DIQHDEPFAG LFTQGMVVHE TYRKADGHFA
610 620 630 640 650
SPAEISITVE GDTRRATLLD GGSPVEIGPI EKMSKSKRNT VDPDDIIGTY
660 670 680 690 700
GADTARWFML SDSPPDRDVI WSEEGVKGAS RFVQRLWRMV NDAAPIAASA
710 720 730 740 750
PAERPASFGA DALTLRKAAH GALDKVLSGI ERLAFNVSLA HIREFSNTLG
760 770 780 790 800
DALARSQTPS PDLAWAIRES TVILVQLFHP MMPHLAEECW TVLGQTGLVS
810 820 830 840 850
EALWPPIEQD LLVEDSITLP VQVNGKKRGD VTVPRDAPTS EIEAAVLALD
860 870
TVKQALGGKP VRKVIVVPQR IVNVVG
Length:876
Mass (Da):97,725
Last modified:July 5, 2004 - v1
Checksum:i8FDD1478FE408442
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX572593 Genomic DNA. Translation: CAE25731.1.
RefSeqiNP_945640.1. NC_005296.1.
WP_011155855.1. NC_005296.1.

Genome annotation databases

EnsemblBacteriaiCAE25731; CAE25731; RPA0287.
GeneIDi2689342.
KEGGirpa:RPA0287.
PATRICi23284707. VBIRhoPal84835_0303.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX572593 Genomic DNA. Translation: CAE25731.1 .
RefSeqi NP_945640.1. NC_005296.1.
WP_011155855.1. NC_005296.1.

3D structure databases

ProteinModelPortali Q6ND22.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 258594.RPA0287.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAE25731 ; CAE25731 ; RPA0287 .
GeneIDi 2689342.
KEGGi rpa:RPA0287.
PATRICi 23284707. VBIRhoPal84835_0303.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200747.
KOi K01869.
OMAi PVIHCPK.
OrthoDBi EOG63Z74X.
PhylomeDBi Q6ND22.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR015413. Methionyl/Leucyl_tRNA_Synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 2 hits.
PF13603. tRNA-synt_1_2. 1 hit.
PF09334. tRNA-synt_1g. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-98 / CGA009.

Entry informationi

Entry nameiSYL_RHOPA
AccessioniPrimary (citable) accession number: Q6ND22
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3