Q6NCQ8 (Q6NCQ8_RHOPA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Inorganic pyrophosphatase HAMAP MF_00209
EC=3.6.1.1 HAMAP MF_00209

Alternative name(s):
Pyrophosphate phospho-hydrolase HAMAP MF_00209

Gene names

Name:	ppa HAMAP MF_00209 EMBL CAE25855.1
Ordered Locus Names:	RPA0411

Organism

Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) [Complete proteome] [HAMAP]

Taxonomic identifier

258594 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Diphosphate + H2O = 2 phosphate. HAMAP MF_00209
Cofactor	Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity. HAMAP MF_00209
Subcellular location	Cytoplasm By similarity HAMAP MF_00209.
Sequence similarities	Belongs to the PPase family. HAMAP MF_00209

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00209
Ligand	Magnesium HAMAP MF_00209 Metal-binding HAMAP MF_00209
Molecular function	Hydrolase HAMAP MF_00209 EMBL CAE25855.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phosphate-containing compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	inorganic diphosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	66	1	Magnesium 1 By similarity HAMAP MF_00209
	Metal binding	71	1	Magnesium 1 By similarity HAMAP MF_00209
	Metal binding	71	1	Magnesium 2 By similarity HAMAP MF_00209
	Metal binding	103	1	Magnesium 1 By similarity HAMAP MF_00209

Sequences

	Sequence		Length	Mass (Da)
	Q6NCQ8 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 4047466D92E6D6FC	FASTA	178	19,752
	10 20 30 40 50 60 MRIDAIPVGV NPPYDVNVII EVPVGGEPIK YEMDKAAGTL VVDRFLYTAM HYPGNYGFIP 70 80 90 100 110 120 HTLSDDGDPC DVLVANTRGI VPGAVMSVRP VGVLYMSDEA GHDEKIIAVP SSKLTQRYDR 130 140 150 160 170 IKTYSDLPEI TLAQFQHFFE HYKDLEPGKW VKVVRWGGAD EAHKLILEGL DRAKKAKG

References

[1]

"Complete genome sequence of the metabolically versatile photosynthetic bacterium Rhodopseudomonas palustris." Larimer F.W., Chain P., Hauser L., Lamerdin J.E., Malfatti S., Do L., Land M.L., Pelletier D.A., Beatty J.T., Lang A.S., Tabita F.R., Gibson J.L., Hanson T.E., Bobst C., Torres y Torres J.L., Peres C., Harrison F.H., Gibson J., Harwood C.S. Nat. Biotechnol. 22:55-61(2004) [PubMed: 14704707] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-98 / CGA009.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX572594 Genomic DNA. Translation: CAE25855.1.
RefSeq	NP_945764.1. NC_005296.1.
3D structure databases
ProteinModelPortal	Q6NCQ8.
SMR	Q6NCQ8. Positions 3-172.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2689589.
GenomeReviews	Gene locus RPA0411 in contig BX571963_GR.
KEGG	rpa:RPA0411.
NMPDR	fig|258594.1.peg.408.
PATRIC	23284975. VBIRhoPal84835_0436.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG529150.
OMA	PNDFNVI.
ProtClustDB	PRK01250.
Enzyme and pathway databases
BioCyc	RPAL258594:RPA0411-MONOMER.
Family and domain databases
HAMAP	MF_00209. Inorganic_PPase. [Tree]
InterPro	IPR008162. Pyrophosphatase. [Graphical view]
Gene3D	G3DSA:3.90.80.10. Pyrophosphatase. 1 hit.
KO	K01507.
PANTHER	PTHR10286. Pyrophosphatase. 1 hit.
Pfam	PF00719. Pyrophosphatase. 1 hit. [Graphical view]
SUPFAM	SSF50324. Pyrophosphatase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q6NCQ8_RHOPA

Accession

Primary (citable) accession number: Q6NCQ8

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)