Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi487MagnesiumUniRule annotation1
Metal bindingi493MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, RNA-binding, Transferase
LigandMagnesium, Metal-binding

Enzyme and pathway databases

BioCyciRPAL258594:G1GT2-449-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
Ordered Locus Names:RPA0432
OrganismiRhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Taxonomic identifieri258594 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
Proteomesi
  • UP000001426 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003298091 – 722Polyribonucleotide nucleotidyltransferaseAdd BLAST722

Proteomic databases

PRIDEiQ6NCN8

Interactioni

Protein-protein interaction databases

STRINGi258594.RPA0432

Structurei

3D structure databases

ProteinModelPortaliQ6NCN8
SMRiQ6NCN8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini554 – 613KHUniRule annotationAdd BLAST60
Domaini623 – 691S1 motifUniRule annotationAdd BLAST69

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C62 Bacteria
COG1185 LUCA
HOGENOMiHOG000218327
KOiK00962
OMAiRYMHNYN
OrthoDBiPOG091H00M0
PhylomeDBiQ6NCN8

Family and domain databases

Gene3Di3.30.1370.10, 1 hit
3.30.230.70, 2 hits
HAMAPiMF_01595 PNPase, 1 hit
InterProiView protein in InterPro
IPR001247 ExoRNase_PH_dom1
IPR015847 ExoRNase_PH_dom2
IPR036345 ExoRNase_PH_dom2_sf
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
IPR012340 NA-bd_OB-fold
IPR012162 PNPase
IPR027408 PNPase/RNase_PH_dom_sf
IPR015848 PNPase_PH_RNA-bd_bac/org-type
IPR036456 PNPase_PH_RNA-bd_sf
IPR020568 Ribosomal_S5_D2-typ_fold
IPR022967 S1_dom
IPR003029 S1_domain
PANTHERiPTHR11252 PTHR11252, 1 hit
PfamiView protein in Pfam
PF00013 KH_1, 1 hit
PF03726 PNPase, 1 hit
PF01138 RNase_PH, 2 hits
PF03725 RNase_PH_C, 1 hit
PF00575 S1, 1 hit
PIRSFiPIRSF005499 PNPase, 1 hit
SMARTiView protein in SMART
SM00322 KH, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF46915 SSF46915, 1 hit
SSF50249 SSF50249, 1 hit
SSF54211 SSF54211, 2 hits
SSF54791 SSF54791, 1 hit
SSF55666 SSF55666, 2 hits
TIGRFAMsiTIGR03591 polynuc_phos, 1 hit
PROSITEiView protein in PROSITE
PS50084 KH_TYPE_1, 1 hit
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

Q6NCN8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFNIHSVEID WGGRPLKLET GKVARQADGA VVATYGETVV LATVVAAKAP
60 70 80 90 100
REGVDFLPLT VDYQEKAYAA GRIPGGYFKR EGRPTEKETL VSRLIDRPIR
110 120 130 140 150
PLFADGWRNE TQVIVTVLSH DMENDPDVLA MVAASAALTL SGVPFKGPIG
160 170 180 190 200
AARVGFINDE YVLNPVLDEM AETQLELVVA GTADAVLMVE SEAKELSEEI
210 220 230 240 250
MLGAVMFGHR HFQPVIDAII DLAEKAAKEP RELTVVDDSE IEKEMLGLVE
260 270 280 290 300
QELRAAYAIP VKQDRYAAVG KVKEKAIAHF FPEGQEPKYD KLRIAGVFKE
310 320 330 340 350
LEAKIVRWNI LDTGKRIDGR DSKTVRNILA QVGVLPRTHG SALFTRGETQ
360 370 380 390 400
AMVVTTLGTG EDEQYVDSLS GTYKETFLLH YNFPPYSVGE TGRLGGTKRR
410 420 430 440 450
EIGHGKLAWR AIHPVLPPHH EFPYTIRVVS EITESNGSSS MASVCGASLA
460 470 480 490 500
LMDAGVPLKR PTAGIAMGLI LEGERFAVLS DILGDEDHLG DMDFKVAGTE
510 520 530 540 550
AGITSLQMDI KIAGITEEIM KVALGQAKDG RIHILGEMSK ALDRARAELG
560 570 580 590 600
EHAPRIETFK IPTDKIREVI GTGGKVIREI VEKTGAKVNI EDDGTVKVAS
610 620 630 640 650
SDGESIKAAI KWIKSIASDP EVGEIYEGTV VKVMEFGAFV NFFGAKDGLV
660 670 680 690 700
HISQLAAGRV QKTSDVVKEG DKVKVKLLGF DDRGKTRLSM KVVDQTTGED
710 720
LEAKQKAEAK AEGEAPAQAA GE
Length:722
Mass (Da):78,285
Last modified:July 5, 2004 - v1
Checksum:iDBDE56D01DA6CD48
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX572594 Genomic DNA Translation: CAE25876.1
RefSeqiWP_011156000.1, NC_005296.1

Genome annotation databases

EnsemblBacteriaiCAE25876; CAE25876; RPA0432
KEGGirpa:RPA0432

Similar proteinsi

Entry informationi

Entry nameiPNP_RHOPA
AccessioniPrimary (citable) accession number: Q6NCN8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health