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Q6NCM9

- TRMB_RHOPA

UniProt

Q6NCM9 - TRMB_RHOPA

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Protein
tRNA (guanine-N(7)-)-methyltransferase
Gene
trmB, RPA0442
Organism
Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei96 – 961S-adenosyl-L-methionine By similarity
Binding sitei121 – 1211S-adenosyl-L-methionine By similarity
Binding sitei148 – 1481S-adenosyl-L-methionine By similarity
Active sitei170 – 1701 By similarity
Binding sitei170 – 1701S-adenosyl-L-methionine By similarity
Binding sitei174 – 1741Substrate By similarity
Binding sitei206 – 2061Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Enzyme and pathway databases

    UniPathwayiUPA00989.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
    Alternative name(s):
    tRNA (guanine(46)-N(7))-methyltransferase
    tRNA(m7G46)-methyltransferase
    Gene namesi
    Name:trmB
    Ordered Locus Names:RPA0442
    OrganismiRhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
    Taxonomic identifieri258594 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
    ProteomesiUP000001426: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 265265tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation
    PRO_0000171383Add
    BLAST

    Proteomic databases

    PRIDEiQ6NCM9.

    Interactioni

    Protein-protein interaction databases

    STRINGi258594.RPA0442.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6NCM9.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0220.
    HOGENOMiHOG000073969.
    KOiK03439.
    OMAiRAFYGRR.
    OrthoDBiEOG6K6VBC.
    PhylomeDBiQ6NCM9.

    Family and domain databases

    Gene3Di3.40.50.150. 1 hit.
    HAMAPiMF_01057. tRNA_methyltr_TrmB.
    InterProiIPR029063. SAM-dependent_MTases-like.
    IPR003358. tRNA_(Gua-N-7)_MeTrfase.
    [Graphical view]
    PfamiPF02390. Methyltransf_4. 1 hit.
    [Graphical view]
    SUPFAMiSSF53335. SSF53335. 1 hit.
    PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6NCM9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAVLYAGRPV QKCERSRLMF NIDQPDSAPD NEDHDGDVVM HGQGSFFGRR    50
    KGHKLRAHQA DLIENLLPHL SLQIDSPAPE PLTTLFDPPV EHMRLEIGFG 100
    GGEHLIAEAL AHPDTGFIGA EPYVNGMAKI LARIEAENIR NIRLFAGDAS 150
    ELLAWVPAGS LARIDLIHPD PWPKRRHWKR RFVQDATVAA MARALTPHGE 200
    FRFVCDIDGY TAWTLAHLLR APCFDWLAQR ADDWRKPWPN YTMTRYGRKA 250
    EREGRRANYL RFERL 265
    Length:265
    Mass (Da):30,230
    Last modified:July 5, 2004 - v1
    Checksum:i9C78AAE665729330
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX572594 Genomic DNA. Translation: CAE25886.1.
    RefSeqiNP_945795.1. NC_005296.1.

    Genome annotation databases

    EnsemblBacteriaiCAE25886; CAE25886; RPA0442.
    GeneIDi2689452.
    KEGGirpa:RPA0442.
    PATRICi23285043. VBIRhoPal84835_0469.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX572594 Genomic DNA. Translation: CAE25886.1 .
    RefSeqi NP_945795.1. NC_005296.1.

    3D structure databases

    ProteinModelPortali Q6NCM9.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 258594.RPA0442.

    Proteomic databases

    PRIDEi Q6NCM9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAE25886 ; CAE25886 ; RPA0442 .
    GeneIDi 2689452.
    KEGGi rpa:RPA0442.
    PATRICi 23285043. VBIRhoPal84835_0469.

    Phylogenomic databases

    eggNOGi COG0220.
    HOGENOMi HOG000073969.
    KOi K03439.
    OMAi RAFYGRR.
    OrthoDBi EOG6K6VBC.
    PhylomeDBi Q6NCM9.

    Enzyme and pathway databases

    UniPathwayi UPA00989 .

    Family and domain databases

    Gene3Di 3.40.50.150. 1 hit.
    HAMAPi MF_01057. tRNA_methyltr_TrmB.
    InterProi IPR029063. SAM-dependent_MTases-like.
    IPR003358. tRNA_(Gua-N-7)_MeTrfase.
    [Graphical view ]
    Pfami PF02390. Methyltransf_4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53335. SSF53335. 1 hit.
    PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-98 / CGA009.

    Entry informationi

    Entry nameiTRMB_RHOPA
    AccessioniPrimary (citable) accession number: Q6NCM9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 19, 2004
    Last sequence update: July 5, 2004
    Last modified: July 9, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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