Q6NCB4 (Q6NCB4_RHOPA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylaminoimidazole-succinocarboxamide synthase 1 HAMAP MF_00137
EC=6.3.2.6 HAMAP MF_00137

Alternative name(s):
SAICAR synthetase 1 HAMAP MF_00137

Gene names

Name:	purC1 HAMAP MF_00137 EMBL CAE26002.1
Ordered Locus Names:	RPA0558

Organism

Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) [Complete proteome] [HAMAP]

Taxonomic identifier

258594 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. HAMAP MF_00137 RuleBase RU000613 SAAS SAAS018236
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2. HAMAP MF_00137 RuleBase RU000613 SAAS SAAS018236
Sequence similarities	Belongs to the SAICAR synthetase family. HAMAP MF_00137 RuleBase RU004193

Ontologies

Keywords
Biological process	Purine biosynthesis HAMAP MF_00137 RuleBase RU000613 SAAS SAAS018236
Ligand	ATP-binding HAMAP MF_00137 SAAS SAAS018236 Nucleotide-binding
Molecular function	Ligase HAMAP MF_00137 RuleBase RU000613 SAAS SAAS018236
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine nucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosylaminoimidazolesuccinocarboxamide synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6NCB4 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 976B10F5CBC1FB6C	FASTA	305	33,568
	10 20 30 40 50 60 MTTMLSSDLP LTKIGRGKVR DIYAVDDDRL LLVTTDRISA FDVVMGETIP MKGAVLTQVS 70 80 90 100 110 120 AFWFGQLGGV VPHHMISADI DEIIAAVPAL QGHRAALAGR TMLCRRTTVF PIECVIRGYI 130 140 150 160 170 180 TGSAWKEYAA SGTLAGEKLA AGLTESERLE PPIFSPATKA ETGHDENITI ARMREIVGDE 190 200 210 220 230 240 AAYTLESMTR AIYTQGEEVA REQGIIIADT KFEFGRDKDG RIILIDEVMT PDSSRFWAAD 250 260 270 280 290 300 TYAPGRSQPS FDKQPLRDYL DAERRAGRWN GEAPPPKLPA EIVEATSKRY LDAYRRLTGT DLVVT

References

[1]

"Complete genome sequence of the metabolically versatile photosynthetic bacterium Rhodopseudomonas palustris." Larimer F.W., Chain P., Hauser L., Lamerdin J.E., Malfatti S., Do L., Land M.L., Pelletier D.A., Beatty J.T., Lang A.S., Tabita F.R., Gibson J.L., Hanson T.E., Bobst C., Torres y Torres J.L., Peres C., Harrison F.H., Gibson J., Harwood C.S. Nat. Biotechnol. 22:55-61(2004) [PubMed: 14704707] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-98 / CGA009.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX572594 Genomic DNA. Translation: CAE26002.1.
RefSeq	NP_945911.1. NC_005296.1.
3D structure databases
HSSP	HSSP built from PDB template 1A48 based on UniProtKB P27616.
ProteinModelPortal	Q6NCB4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2691372.
GenomeReviews	Gene locus RPA0558 in contig BX571963_GR.
KEGG	rpa:RPA0558.
NMPDR	fig|258594.1.peg.555.
PATRIC	23285289. VBIRhoPal84835_0590.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG555040.
OMA	SSRIWDG.
ProtClustDB	PRK13961.
Enzyme and pathway databases
BioCyc	RPAL258594:RPA0558-MONOMER.
Family and domain databases
HAMAP	MF_00137. SAICAR_synth. [Tree]
InterPro	IPR013816. ATP_grasp_subdomain_2. IPR001636. SAICAR_synth. IPR018236. SAICAR_synthetase_CS. [Graphical view]
Gene3D	G3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit.
KO	K01923.
PANTHER	PTHR11609. SAICAR_synt. 1 hit.
Pfam	PF01259. SAICAR_synt. 1 hit. [Graphical view]
TIGRFAMs	TIGR00081. PurC. 1 hit.
PROSITE	PS01057. SAICAR_SYNTHETASE_1. 1 hit. PS01058. SAICAR_SYNTHETASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q6NCB4_RHOPA

Accession

Primary (citable) accession number: Q6NCB4

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)