Q6NA55 (MQO_RHOPA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	RPA1331

Organism

Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) [Complete proteome] [HAMAP]

Taxonomic identifier

258594 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length	497 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 497	497	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_0000325512

Sequences

	Sequence		Length	Mass (Da)
	Q6NA55 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 4391035043904442	FASTA	497	54,007
	10 20 30 40 50 60 MSQIPETSDI VLIGAGIMSA TLGTVLKELE PSLSVTMLET LHDCGQESSQ AWNNAGTGHA 70 80 90 100 110 120 ANCELNYTPQ RPDGSVDITK ALEVNTEFDI SRQLWAHLVT KGAIPDPRAF LHPCPHMSFV 130 140 150 160 170 180 WGDDNVAFLR QRHREMAAHH CYHGMEFSED SAQIAAWAPL IIEGRKPGQP IAATRIISGA 190 200 210 220 230 240 DVDYGALTHL LVKQLQAQSG FSVHYKHRVV ALARGDDGRW LVTVENVASA ERTTISARFV 250 260 270 280 290 300 FAGAGGGALD ILQKSGIPEG NGYAGFPVSG IWLRCDVDDI SVRHHAKVYG KAAHGSPPMS 310 320 330 340 350 360 VPHLDTRIIG GKRSLLFGPY AGFSSKFLKH GSYADLLRSI EPGNILPMLA VARDDWQLSE 370 380 390 400 410 420 YLIGQVLQTS EHQFAALQGF FPRAQREDWQ RAVAGQRVQI IKPDPQHTGV LEFGTELVAS 430 440 450 460 470 480 ADNSFVALLG ASPGASTAAF IAMEVLQKCF DDRLTPDGWL GALKQMIPTY GIDLKQDAAA 490 CRDSRARTAK VLQLDFV

References

[1]

"Complete genome sequence of the metabolically versatile photosynthetic bacterium Rhodopseudomonas palustris." Larimer F.W., Chain P., Hauser L., Lamerdin J.E., Malfatti S., Do L., Land M.L., Pelletier D.A., Beatty J.T., Lang A.S., Tabita F.R., Gibson J.L., Hanson T.E., Bobst C., Torres y Torres J.L., Peres C., Harrison F.H., Gibson J., Harwood C.S. Nat. Biotechnol. 22:55-61(2004) [PubMed: 14704707] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-98 / CGA009.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX572597 Genomic DNA. Translation: CAE26774.1.
RefSeq	NP_946681.1. NC_005296.1.
3D structure databases
ProteinModelPortal	Q6NA55.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2693488.
GenomeReviews	Gene locus RPA1331 in contig BX571963_GR.
KEGG	rpa:RPA1331.
NMPDR	fig|258594.1.peg.1325.
PATRIC	23286895. VBIRhoPal84835_1387.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289663.
OMA	NTQFEVS.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	RPAL258594:RPA1331-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_RHOPA

Accession

Primary (citable) accession number: Q6NA55

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program