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Reviewed, UniProtKB/Swiss-Prot Q6N8F5 (PQQC_RHOPA)

Last modified February 9, 2010. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Pyrroloquinoline-quinone synthase
    EC=1.3.3.11
Alternative name(s):
    Coenzyme PQQ synthesis protein C
    Pyrroloquinoline quinone biosynthesis protein C
Gene names
Name: pqqC
Ordered Locus Names: RPA1948
OrganismRhodopseudomonas palustris [Complete proteome] [HAMAP]
Taxonomic identifier1076 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

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Protein attributes

Sequence length254 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity. HAMAP MF_00654

Catalytic activity

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O. HAMAP MF_00654

Pathway

Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. HAMAP MF_00654

Sequence similarities

Belongs to the pqqC family.

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Ontologies

Keywords
   Biological processPQQ biosynthesis
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

pyrroloquinoline quinone biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionpyrroloquinoline-quinone synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 254254Pyrroloquinoline-quinone synthase HAMAP MF_00654
PRO_0000219987

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Sequences

Sequence LengthMass (Da)Tools
Q6N8F5-1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: FCE79ADBCAA1E77F

FASTA25428,618
        10         20         30         40         50         60 
MNAMTAFSLN GAAPLANADE LEAALRQIGA ARYHNLHPFH RLLHGGKLNK GQVQAWALNR 

        70         80         90        100        110        120 
YYYQSSIPIK DAVVISRFRD RATRVEWRHR IEDHDGDLSS EGGIERWLKL TEGLGLDSGY 

       130        140        150        160        170        180 
VESTQGILPA TRFAVDAYVH FVRDRTPLEA IASSLTELFA PNLHEERIAG MLAHYDFVNP 

       190        200        210        220        230        240 
EIMSYFKRRL EQAPRDADFA LRHVKQHATT PAEREAVCNA LIFKTNVLWA QLDALHHAYV 

       250 
DGHIPPGAFV PQGF

« Hide

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References

[1]"Complete genome sequence of the metabolically versatile photosynthetic bacterium Rhodopseudomonas palustris."
Larimer F.W., Chain P., Hauser L., Lamerdin J.E., Malfatti S., Do L., Land M.L., Pelletier D.A., Beatty J.T., Lang A.S., Tabita F.R., Gibson J.L., Hanson T.E., Bobst C., Torres y Torres J.L., Peres C., Harrison F.H., Gibson J., Harwood C.S.
Nat. Biotechnol. 22:55-61(2004) [PubMed: 14704707] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-98 / CGA009.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX572599 Genomic DNA. Translation: CAE27389.1.
RefSeqNP_947293.1.

3D structure databases

SMRQ6N8F5. Positions 15-252.
ModBaseSearch...

Genome annotation databases

GeneID2688798.
KEGGrpa:RPA1948.
NMPDRfig|258594.1.peg.1936.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG288944.
OMAFRDRATR.

Enzyme and pathway databases

BioCycRPAL258594:RPA1948-MONOMER.
BRENDA1.3.3.11. 373.

Family and domain databases

HAMAPMF_00654. PQQ_syn_PqqC.
[Tree]
InterProIPR016084. Haem_Oase-like_multi-hlx.
IPR011845. PQQ_synth_PqqC.
IPR004305. TENA/THI4/PQQ_synth_PqqC.
[Graphical view]
Gene3DG3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
PfamPF03070. TENA_THI-4. 1 hit.
[Graphical view]
TIGRFAMsTIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNetSearch...

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Entry information

Entry namePQQC_RHOPA
AccessionPrimary (citable) accession number: Q6N8F5
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: July 5, 2004
Last modified: February 9, 2010
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents