Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

D-alanine--D-alanine ligase

Gene

ddlA

Organism
Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cell wall formation.SAAS annotation

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

Cofactori

Protein has several cofactor binding sites:
  • Mg2+SAAS annotation
  • Mn2+SAAS annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseSAAS annotationImported
Biological processCell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciRPAL258594:G1GT2-3630-MONOMER
UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
D-alanine--D-alanine ligaseSAAS annotation (EC:6.3.2.4SAAS annotation)
Gene namesi
Name:ddlAImported
Ordered Locus Names:RPA3525Imported
OrganismiRhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)Imported
Taxonomic identifieri258594 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
Proteomesi
  • UP000001426 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi258594.RPA3525

Structurei

3D structure databases

ProteinModelPortaliQ6N415
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini128 – 321ATP-graspInterPro annotationAdd BLAST194

Sequence similaritiesi

Belongs to the D-alanine--D-alanine ligase family.SAAS annotation

Phylogenomic databases

eggNOGiENOG4105CPF Bacteria
COG1181 LUCA
HOGENOMiHOG000011592
KOiK01921
OMAiMQGLLEC
OrthoDBiPOG091H00GT
PhylomeDBiQ6N415

Family and domain databases

Gene3Di3.30.1490.20, 1 hit
InterProiView protein in InterPro
IPR011761 ATP-grasp
IPR013815 ATP_grasp_subdomain_1
IPR000291 D-Ala_lig_Van_CS
IPR011095 Dala_Dala_lig_C
IPR011127 Dala_Dala_lig_N
IPR016185 PreATP-grasp_dom_sf
PfamiView protein in Pfam
PF07478 Dala_Dala_lig_C, 1 hit
PF01820 Dala_Dala_lig_N, 1 hit
SUPFAMiSSF52440 SSF52440, 1 hit
PROSITEiView protein in PROSITE
PS50975 ATP_GRASP, 1 hit
PS00844 DALA_DALA_LIGASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q6N415-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRHTILFGGT SKERLVSVAS AQALHSALPD ADLWFWNDDD RVHAVSAQAL
60 70 80 90 100
LAHARPFEEA FVPDGEDIGP LETALDRAAA EQRLLVLGLH GGVAENGELQ
110 120 130 140 150
AMCELRRVPF TGSGSAASHL AFDKVAAKRF AAIAGVRTVT GIALADAEAA
160 170 180 190 200
LEAHGRLIAK PACDGSSYGL FFINAKQDLV AVRHAAKTED YLIEPFVAGV
210 220 230 240 250
EATCGVLEAE DGSLRALPPI EIVPADGGFD YTAKYLAKST QEICPGRFAP
260 270 280 290 300
EIASAIMDYA VRAHRVMSCR GYSRSDFIVG KDGPIFLETN TLPGLTKASL
310 320
YPKALNALGI PFVDFLRGQI ALAERAVRS
Length:329
Mass (Da):35,057
Last modified:July 5, 2004 - v1
Checksum:i3C2CAACFC4F65AFF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX572604 Genomic DNA Translation: CAE28966.1
RefSeqiWP_011159065.1, NC_005296.1

Genome annotation databases

EnsemblBacteriaiCAE28966; CAE28966; RPA3525
KEGGirpa:RPA3525

Similar proteinsi

Entry informationi

Entry nameiQ6N415_RHOPA
AccessioniPrimary (citable) accession number: Q6N415
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: April 25, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health