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Q6N2A3 (TYPH_RHOPA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative thymidine phosphorylase

EC=2.4.2.4
Alternative name(s):
TdRPase
Gene names
Ordered Locus Names:RPA4147
OrganismRhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) [Complete proteome] [HAMAP]
Taxonomic identifier258594 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas

Protein attributes

Sequence length514 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_00703

Sequence similarities

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

Sequence caution

The sequence CAE29588.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 514514Putative thymidine phosphorylase HAMAP-Rule MF_00703
PRO_0000314713

Sequences

Sequence LengthMass (Da)Tools
Q6N2A3 [UniParc].

Last modified January 15, 2008. Version 2.
Checksum: A2FD6F004F8FFE9C

FASTA51454,680
        10         20         30         40         50         60 
MNAPDLTRPP LTIRRISLDT GRENVAVISR RSRALRPEVF RGFSRVELRI NSKVLLATLM 

        70         80         90        100        110        120 
ITDDDAMIGP DEVGLSEPAF RRFNEPVGSA VSVTPARSPA SLDAVRAKIQ GHTLSAAEIT 

       130        140        150        160        170        180 
AIVDDLAHFR YSDMEIAAFL ISAARFTTTD ELLALVGAMA SVGTKLTWDT PIVVDKHCIG 

       190        200        210        220        230        240 
GIPGNRTTMI VVPIVAAHGL MIPKTSSRAI TSPAGTADTM ELLARVDLDV EQMKQVVHAC 

       250        260        270        280        290        300 
GGCLVWGGHV NLSPADDILI SVERPLSLDT PEQMVASIMS KKLAAGSTRL LIDFPVGPSA 

       310        320        330        340        350        360 
KVTNANEAMR LRKLFEFVGD HFGISVEVVT TDGRQPIGRG IGPVLEARDV MAVLGNEPGA 

       370        380        390        400        410        420 
PADLREKSLR LAAHLLEYDP KLRGGTGYAR AKELLDSGAA LKKMQQIIDA QGPSPCPAEL 

       430        440        450        460        470        480 
GSYAADVLAA ADGVVNGIDC LRINRLARSA GAPVAKGAGI DLFKKIGDRV EKGEPLYRVY 

       490        500        510 
ASDRSEFDLA LAAAQAESGF AINHHTPADV DLVS 

« Hide

References

[1]"Complete genome sequence of the metabolically versatile photosynthetic bacterium Rhodopseudomonas palustris."
Larimer F.W., Chain P., Hauser L., Lamerdin J.E., Malfatti S., Do L., Land M.L., Pelletier D.A., Beatty J.T., Lang A.S., Tabita F.R., Gibson J.L., Hanson T.E., Bobst C., Torres y Torres J.L., Peres C., Harrison F.H., Gibson J., Harwood C.S.
Nat. Biotechnol. 22:55-61(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-98 / CGA009.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX572606 Genomic DNA. Translation: CAE29588.1. Different initiation.
RefSeqNP_949483.1. NC_005296.1.

3D structure databases

ProteinModelPortalQ6N2A3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING258594.RPA4147.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAE29588; CAE29588; RPA4147.
GeneID2690431.
KEGGrpa:RPA4147.
PATRIC23292875. VBIRhoPal84835_4351.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0213.
HOGENOMHOG000252767.
KOK00758.
OrthoDBEOG61ZTGG.

Family and domain databases

Gene3D3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPMF_00703. Thymid_phosp_2.
InterProIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERPTHR10515. PTHR10515. 1 hit.
PfamPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFPIRSF000478. TP_PyNP. 1 hit.
SMARTSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTYPH_RHOPA
AccessionPrimary (citable) accession number: Q6N2A3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: May 14, 2014
This is version 62 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families