Q6N0W5 (F16PA_RHOPA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Fructose-1,6-bisphosphatase class 1
Short name=FBPase class 1
EC=3.1.3.11

Alternative name(s):
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Gene names

Name:	fbp
Ordered Locus Names:	RPA4645

Organism

Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) [Complete proteome] [HAMAP]

Taxonomic identifier

258594 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855
Cofactor	Binds 2 magnesium ions per subunit By similarity. HAMAP MF_01855
Pathway	Carbohydrate biosynthesis; Calvin cycle. HAMAP MF_01855
Subunit structure	Homotetramer By similarity. HAMAP MF_01855
Subcellular location	Cytoplasm Potential HAMAP MF_01855.
Sequence similarities	Belongs to the FBPase class 1 family.

Ontologies

Keywords
Biological process	Calvin cycle Carbohydrate metabolism
Cellular component	Cytoplasm
Ligand	Magnesium Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	reductive pentose-phosphate cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 343	343	Fructose-1,6-bisphosphatase class 1 HAMAP MF_01855		PRO_0000364674
Regions
	Region	112 – 115	4	Substrate binding By similarity
Sites
	Metal binding	90	1	Magnesium 1 By similarity
	Metal binding	109	1	Magnesium 1 By similarity
	Metal binding	109	1	Magnesium 2 By similarity
	Metal binding	111	1	Magnesium 1; via carbonyl oxygen By similarity
	Metal binding	112	1	Magnesium 2 By similarity
	Metal binding	271	1	Magnesium 2 By similarity
	Binding site	199	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6N0W5 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 4C0B5D61C5841B5B	FASTA	343	36,633
	10 20 30 40 50 60 MDQGQTLSVL LDSYAVDPQK KAVAAAVGAI AAGSIEISEL IGQGALAGIT GAAHGGSNAD 70 80 90 100 110 120 GDVQKDLDVK AEQIIVKSLK DVPYAALASE ESDTLLDGDP NAPISIAYDP LDGSSNIDTN 130 140 150 160 170 180 MTVGTIFSII PNQPGVKPFT AAGSCQIAAG FVVYGPQTSL VLTLGDGVNI FTLDRKAKVY 190 200 210 220 230 240 RLIRERVKVP ADTAEYAVNA SNHRHWEQPI RDFVDECIAG ADGPRAKDFN MRWIGSLVAE 250 260 270 280 290 300 VYRILTRGGV FLYPGDNRPG YGNGRLRLLY ETHPMSFVME QAGGAASTGR ERVLDLTAKT 310 320 330 340 IHQRSPLIMG SIDKVKRIEL LHTDPSAASR SAPLFARRGL FRV

References

[1]

"Complete genome sequence of the metabolically versatile photosynthetic bacterium Rhodopseudomonas palustris." Larimer F.W., Chain P., Hauser L., Lamerdin J.E., Malfatti S., Do L., Land M.L., Pelletier D.A., Beatty J.T., Lang A.S., Tabita F.R., Gibson J.L., Hanson T.E., Bobst C., Torres y Torres J.L., Peres C., Harrison F.H., Gibson J., Harwood C.S. Nat. Biotechnol. 22:55-61(2004) [PubMed: 14704707] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-98 / CGA009.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX572607 Genomic DNA. Translation: CAE30085.1.
RefSeq	NP_949979.1. NC_005296.1.
3D structure databases
HSSP	HSSP built from PDB template 2GQ1 based on UniProtKB P0A993.
ProteinModelPortal	Q6N0W5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2689950.
GenomeReviews	Gene locus RPA4645 in contig BX571963_GR.
KEGG	rpa:RPA4645.
NMPDR	fig|258594.1.peg.4622.
PATRIC	23293941. VBIRhoPal84835_4877.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG731261.
OMA	HWEAPVQ.
ProtClustDB	PRK09293.
Enzyme and pathway databases
BioCyc	RPAL258594:RPA4645-MONOMER.
Family and domain databases
HAMAP	MF_01855. FBPase_class1. [Tree]
InterPro	IPR000146. FBPase_class-1/SBPase. IPR020548. Fructose_bisphosphatase_AS. [Graphical view]
KO	K03841.
PANTHER	PTHR11556. In_FB_phphtase. 1 hit.
Pfam	PF00316. FBPase. 1 hit. [Graphical view]
PIRSF	PIRSF000904. FBPtase_SBPase. 1 hit.
PRINTS	PR00115. F16BPHPHTASE.
PROSITE	PS00124. FBPASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F16PA_RHOPA

Accession

Primary (citable) accession number: Q6N0W5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program