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Q6N089 (Q6N089_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:DKFZp686P15220 EMBL CAE45781.1
OrganismHomo sapiens (Human) EMBL CAE45781.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length472 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Sequences

Sequence LengthMass (Da)Tools
Q6N089 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 26CB340D0046D279

FASTA47251,725
        10         20         30         40         50         60 
MELGLTWIFL LAILKGVQCE VQLVESGGGL VQPGRSLRLS CAASGFTFDD YAMHWVRQAP 

        70         80         90        100        110        120 
GKGLEWVSGI SWNSGSIAYA DSVKGRFTIS RDNGKNSLYL QMNSLRAEDT ALYYCAKEIG 

       130        140        150        160        170        180 
AHNFYYYGMD VWGQGTTVTV SSASTKGPSV FPLAPSSKST SGGTAALGCL VKDYFPEPVT 

       190        200        210        220        230        240 
VSWNSGALTS GVHTFPAVLQ SSGLYSLSSV VTVPSSSLGT QTYICNVNHK PSNTKVDKRV 

       250        260        270        280        290        300 
EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF 

       310        320        330        340        350        360 
NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT 

       370        380        390        400        410        420 
ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP 

       430        440        450        460        470 
PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GK 

« Hide

References

[1]The German cDNA Consortium
Wambutt R., Heubner D., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S.
Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Rectum tumor EMBL CAE45781.1.
[2]"Conformational isomerism can limit antibody catalysis."
Debler E.W., Muller R., Hilvert D., Wilson I.A.
J. Biol. Chem. 283:16554-16560(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 20-246.
[3]"Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2."
Liao H.X., Bonsignori M., Alam S.M., McLellan J.S., Tomaras G.D., Moody M.A., Kozink D.M., Hwang K.K., Chen X., Tsao C.Y., Liu P., Lu X., Parks R.J., Montefiori D.C., Ferrari G., Pollara J., Rao M., Peachman K.K. expand/collapse author list , Santra S., Letvin N.L., Karasavvas N., Yang Z.Y., Dai K., Pancera M., Gorman J., Wiehe K., Nicely N.I., Rerks-Ngarm S., Nitayaphan S., Kaewkungwal J., Pitisuttithum P., Tartaglia J., Sinangil F., Kim J.H., Michael N.L., Kepler T.B., Kwong P.D., Mascola J.R., Nabel G.J., Pinter A., Zolla-Pazner S., Haynes B.F.
Immunity 38:176-186(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS) OF 20-247.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX640627 mRNA. Translation: CAE45781.1.
UniGeneHs.510635.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3CFJX-ray2.60B/D/F/H20-246[»]
3CFKX-ray2.60B/D/F/H/I/K/N/P20-246[»]
4HPYX-ray1.50H20-247[»]
ProteinModelPortalQ6N089.
SMRQ6N089. Positions 20-472.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ6N089. 1 interaction.
MINTMINT-3976215.

Proteomic databases

PeptideAtlasQ6N089.
PRIDEQ6N089.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG005814.

Family and domain databases

Gene3D2.60.40.10. 4 hits.
InterProIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamPF07654. C1-set. 3 hits.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTSM00407. IGc1. 2 hits.
SM00406. IGv. 1 hit.
[Graphical view]
PROSITEPS50835. IG_LIKE. 4 hits.
PS00290. IG_MHC. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ6N089.

Entry information

Entry nameQ6N089_HUMAN
AccessionPrimary (citable) accession number: Q6N089
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.