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Protein
Submitted name:

Putative uncharacterized protein DKFZp686P15220

Gene

DKFZp686P15220

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized protein DKFZp686P15220Imported
Gene namesi
Name:DKFZp686P15220Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiQ6N089.
PRIDEiQ6N089.

Interactioni

Protein-protein interaction databases

IntActiQ6N089. 1 interaction.
MINTiMINT-3976215.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3CFJX-ray2.60B/D/F/H20-246[»]
3CFKX-ray2.60B/D/F/H/I/K/N/P20-246[»]
4HPYX-ray1.50H20-247[»]
ProteinModelPortaliQ6N089.
SMRiQ6N089. Positions 20-472.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ6N089.

Family & Domainsi

Keywords - Domaini

Immunoglobulin domainSAAS annotation, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOVERGENiHBG005814.

Family and domain databases

Gene3Di2.60.40.10. 4 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamiPF07654. C1-set. 3 hits.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 2 hits.
SM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 4 hits.
PS00290. IG_MHC. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6N089-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELGLTWIFL LAILKGVQCE VQLVESGGGL VQPGRSLRLS CAASGFTFDD
60 70 80 90 100
YAMHWVRQAP GKGLEWVSGI SWNSGSIAYA DSVKGRFTIS RDNGKNSLYL
110 120 130 140 150
QMNSLRAEDT ALYYCAKEIG AHNFYYYGMD VWGQGTTVTV SSASTKGPSV
160 170 180 190 200
FPLAPSSKST SGGTAALGCL VKDYFPEPVT VSWNSGALTS GVHTFPAVLQ
210 220 230 240 250
SSGLYSLSSV VTVPSSSLGT QTYICNVNHK PSNTKVDKRV EPKSCDKTHT
260 270 280 290 300
CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF
310 320 330 340 350
NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN
360 370 380 390 400
KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS
410 420 430 440 450
DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC
460 470
SVMHEALHNH YTQKSLSLSP GK
Length:472
Mass (Da):51,725
Last modified:July 5, 2004 - v1
Checksum:i26CB340D0046D279
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX640627 mRNA. Translation: CAE45781.1.
UniGeneiHs.510635.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX640627 mRNA. Translation: CAE45781.1.
UniGeneiHs.510635.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3CFJX-ray2.60B/D/F/H20-246[»]
3CFKX-ray2.60B/D/F/H/I/K/N/P20-246[»]
4HPYX-ray1.50H20-247[»]
ProteinModelPortaliQ6N089.
SMRiQ6N089. Positions 20-472.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ6N089. 1 interaction.
MINTiMINT-3976215.

Proteomic databases

PeptideAtlasiQ6N089.
PRIDEiQ6N089.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG005814.

Miscellaneous databases

EvolutionaryTraceiQ6N089.

Family and domain databases

Gene3Di2.60.40.10. 4 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamiPF07654. C1-set. 3 hits.
PF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 2 hits.
SM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 4 hits.
PS00290. IG_MHC. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. The German cDNA Consortium
    Wambutt R., Heubner D., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S.
    Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Rectum tumorImported.
  2. "Conformational isomerism can limit antibody catalysis."
    Debler E.W., Muller R., Hilvert D., Wilson I.A.
    J. Biol. Chem. 283:16554-16560(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) OF 20-246, ACTIVE SITE.
  3. Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS) OF 20-247, ACTIVE SITE.

Entry informationi

Entry nameiQ6N089_HUMAN
AccessioniPrimary (citable) accession number: Q6N089
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 4, 2015
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.