Q6N030 (Q6N030_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein DKFZp686I15212 EMBL CAE45841.1

Gene names

Name:

DKFZp686I15212 EMBL CAE45841.1

Organism

Homo sapiens (Human) EMBL CAE45841.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	518 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS003596
Technical term	3D-structure PDB 2NY1 PDB 2NY3 PDB 2NY6
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Region	62 – 65	4	Sucrose binding PDB 2NY1 PDB 2NY3 PDB 2NY6

Sequences

	Sequence		Length	Mass (Da)
	Q6N030 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 93B5F98613BF6382	FASTA	518	57,020
	10 20 30 40 50 60 MDWTWRILFL VTAATGAHSQ VHLVQSGAEV KKPGASVKVS CTASGYPFTN HFINWVRQAP 70 80 90 100 110 120 GQSLEWMGWI NTGNGNTKYS QKFQGRVTIT RDTWTTTAYM DLSSLRSEDT AVYWCARDAP 130 140 150 160 170 180 QGVTTTYFDY WGQGTLVTVS SASTKGPSVF PLAPCSRSTS GGTAALGCLV KDYFPEPVTV 190 200 210 220 230 240 SWNSGALTSG VHTFPAVLQS SGLYSLSSVV TVPSSSLGTQ TYTCNVNHKP SNTKVDKRVE 250 260 270 280 290 300 LKTPLGDTTH TCPRCPEPKP CDTPPPCPRC PEPKSCDTPP PCPRCPEPKS CDTPPPCPRC 310 320 330 340 350 360 PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVQFKWYV DGVEVHNAKT 370 380 390 400 410 420 KPREEQYNST FRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKT KGQPREPQVY 430 440 450 460 470 480 TLPPSREEMT KNQVSLTCLV KGFYPSDIAV EWESSGQPEN NYNTTPPMLD SDGSFFLYSK 490 500 510 LTVDKSRWQQ GNIFSCSVMH EALHNRFTQK SLSLSPGK

References

[1]	The German cDNA Consortium Poustka A., Albert R., Moosmayer P., Schupp I., Wellenreuther R., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S. Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Rectum tumor EMBL CAE45841.1.
[2]	"Structural definition of a conserved neutralization epitope on HIV-1 gp120." Zhou T., Xu L., Dey B., Hessell A.J., Van Ryk D., Xiang S.H., Yang X., Zhang M.Y., Zwick M.B., Arthos J., Burton D.R., Dimitrov D.S., Sodroski J., Wyatt R., Nabel G.J., Kwong P.D. Nature 445:732-737(2007) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.99 ANGSTROMS) OF 23-240 IN COMPLEX WITH SUCROSE.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

BX640724 mRNA. Translation: CAE45841.1.

IPI

IPI00418153.

UniGene

Hs.510635.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2NY1	X-ray	1.99	D	23-240	[»]
2NY3	X-ray	2.00	D	23-240	[»]
2NY6	X-ray	2.80	D	23-240	[»]

ProteinModelPortal

Q6N030.

SMR

Q6N030. Positions 20-518.

ModBase

Search...

Protein-protein interaction databases

STRING

Q6N030.

Proteomic databases

PRIDE

Q6N030.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Phylogenomic databases

HOVERGEN

HBG005814.

Family and domain databases

Gene3D

2.60.40.10. 4 hits.

InterPro

IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]

Pfam

PF07654. C1-set. 3 hits.
PF07686. V-set. 1 hit.
[Graphical view]

SMART

SM00407. IGc1. 2 hits.
SM00406. IGv. 1 hit.
[Graphical view]

PROSITE

PS50835. IG_LIKE. 4 hits.
PS00290. IG_MHC. 2 hits.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q6N030.

Entry information

Entry name

Q6N030_HUMAN

Accession

Primary (citable) accession number: Q6N030

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	March 6, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.