Q6MZK8 (Q6MZK8_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein DKFZp686K06110 EMBL CAE46022.1

Gene names

Name:

DKFZp686K06110 EMBL CAE46022.1

Organism

Homo sapiens (Human) EMBL CAE46022.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	2060 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 C-type lectin domain. SAAS SAAS001304

Ontologies

Keywords
Domain	EGF-like domain RuleBase RU000459 SAAS SAAS000436 Repeat SAAS SAAS001304 Sushi SAAS SAAS000436
Ligand	Lectin SAAS SAAS001304
PTM	Disulfide bond SAAS SAAS000436
Gene Ontology (GO)
Molecular_function	calcium ion binding Inferred from electronic annotation. Source: InterPro carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6MZK8 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: D33CB7F70465D02E	FASTA	2,060	226,423
	10 20 30 40 50 60 MSDLSVIGHP IDSESKEDEP CSEETDPVHD LMAEILPEFP DIIEIDLYHS EENEEEEEEC 70 80 90 100 110 120 ANATDVTTTP SVQYINGKHL VTTVPKDPEA AEARRGQFES VAPSQNFSDS SESDTHPFVI 130 140 150 160 170 180 AKTELSTAVQ PNESTETTES LEVTWKPETY PETSEHFSGG EPDVFPTVPF HEEFESGTAR 190 200 210 220 230 240 KGAESVTERD TEVGHQAHEH TEPVSLFPEE SSGEIAIDQE SQKIAFARAT EVTFGEEVEK 250 260 270 280 290 300 STSVTYTPTI VPSSASAYVS EEEAVTLIGN PWPDDLLSTK ESWVEATPRQ VVELSGSSSI 310 320 330 340 350 360 PITEGSGEAE EDEDTMFTMV TDLSQRNTTD TLITLDTSRI ITESFFEVPA TTIYPVSEQP 370 380 390 400 410 420 SAKVVPTKFV SETDTSEWIS STTVEEKKRK EEEGTTGTAS TFEVYSSTQR SDQLILPFEL 430 440 450 460 470 480 ESPNVATSSD SGTRKSFMSL TTPTRSEREM TDSTPVFTET NTLENLGAQT TEHSSIHQPG 490 500 510 520 530 540 VQEGLTTLPH SPASVFMEQG SGEAAADPET TTVSSFSLNV EYAIQAEKEV AGTLSPHVET 550 560 570 580 590 600 TFSTEPTGLV LSTVMDRVVA ENITQTSREI AISERLGEPN YGAEIRGFST GFPLEEDFSG 610 620 630 640 650 660 DFREYSTVSH PIAKEETVMM EGSGDAAFRD TQTSPSTVPT SVHISHISDS EGPSSTMVST 670 680 690 700 710 720 SAFPWEEFTS SAEGSGEQLV TVSSSVVPVL PSAVQKFSGT ASSIIDEGLG EVGTVNEIDR 730 740 750 760 770 780 RSTILPTAEV EGTKAPVEKE EVKVSGTVST NFPQTIEPAK LWSRQEVNPV RQEIESETTS 790 800 810 820 830 840 EEQIQEEKSF ESPQNSPATE QTIFDSQTFT ETELKTTDYS VLTTKKTYSD DKEMKEEDTS 850 860 870 880 890 900 LVNMSTPDPD ANGLESYTTL PEATEKSHFF LATALVTESI PAEHVVTDSP IKKEESTKHF 910 920 930 940 950 960 PKGMRPTIQE SDTELLFSGL GSGEEVLPTL PTESVNFTEV EQINNTLYPH TSQVESTSSD 970 980 990 1000 1010 1020 KIEDYNRMEN VAKEVGPLVS QTDIFEGSGS VTSTTLIEIL SDTGAEGPTV APLPFSTDIG 1030 1040 1050 1060 1070 1080 HPQNQTVRWA EEIQTSRPQT ITEQDSNKNS STAEINETTT SSTDFLARAY GFEMAKEFVT 1090 1100 1110 1120 1130 1140 SAPKPSDLYY EPSGEGSGEV DIVDSFHTSA TTQATRQESS TTFVSDGSLE KHPEVPSAKA 1150 1160 1170 1180 1190 1200 VTADGFPTVS VMLPLHSEQN KSSPDPTSTL SNTVSYERST DGSFQDRFRE FEDSTLKPNR 1210 1220 1230 1240 1250 1260 KKPTENIIID LDKEDKDLIL TITESTILEI LPELTSDKNT IIDIDHTKPV YEDILGMQTD 1270 1280 1290 1300 1310 1320 IDTEVPSEPH DSNDESNDDS TQVQEIYEAA VNLSLTEETF EGSADVLASY TQATHDESMT 1330 1340 1350 1360 1370 1380 YEDRSQLDHM GFHFTTGIPA PSTETELDVL LPTATSLPIP RKSATVIPEI EGIKAEAKAL 1390 1400 1410 1420 1430 1440 DDMFESSTLS DGQAIADQSE IIPTLGQFER TQEEYEDKKH AGPSFQPEFS SGAEEALVDH 1450 1460 1470 1480 1490 1500 TPYLSIATTH LMDQSVTEVP DVMEGSNPPY YTDTTLAVST FAKLSSQTPS SPLTIYSGSE 1510 1520 1530 1540 1550 1560 ASGHTEIPQP SALPGIDVGS SVMSPQDSFK EIHVNIEATF KPSSEEYLHI TEPPSLSPDT 1570 1580 1590 1600 1610 1620 KLEPSEDDGK PELLEEMEAS PTELIAVEGT EILQDFQNKT YGQVSGEAIK MFPTIKTPEA 1630 1640 1650 1660 1670 1680 GTVITTADEI ELEGATQWPH STSASATYGV EAGVVPWLSP QTSERPTLSS SPEINPETQA 1690 1700 1710 1720 1730 1740 ALIRGQDSTI AASEQQVAAR ILDSNDQATV NPVEFNTEVA TPPFSLLETS NETDFLIGIN 1750 1760 1770 1780 1790 1800 EESVEGTAIY LPGPDRCKMN PCLNGGTCYP TETSYVCTCV PGYSGDQCEL DFDECHSNPC 1810 1820 1830 1840 1850 1860 RNGATCVDGF NTFRCLCLPS YVGALCEQDT ETCDYGWHKF QGQCYKYFAH RRTWDAAERE 1870 1880 1890 1900 1910 1920 CRLQGAHLTS ILSHEEQMFV NRVGHDYQWI GLNDKMFEHD FRWTDGSTLQ YENWRPNQPD 1930 1940 1950 1960 1970 1980 SFFSAGEDCV VIIWHENGQW NDVPCNYHLT YTCKKGTVAC GQPPVVENAK TFGKMKPRYE 1990 2000 2010 2020 2030 2040 INSLIRYHCK DGFIQRHLPT IRCLGNGRWA IPKITCMNPS AYQRTYSMKY FKNSSSAKDN 2050 2060 SINTSKHDHR WSRRWQESRR

References

[1]	The German Human cDNA Consortium Koehrer K., Beyer A., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S. Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Human fetal kidney EMBL CAE46022.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX641036 mRNA. Translation: CAE46022.1.
IPI	IPI00215628.
RefSeq	NP_001157569.1. NM_001164097.1.
UniGene	Hs.643801.
3D structure databases
HSSP	HSSP built from PDB template 1A3P based on UniProtKB P01132.
ProteinModelPortal	Q6MZK8.
SMR	Q6MZK8. Positions 1831-1956.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6MZK8.
Proteomic databases
PRIDE	Q6MZK8.
Protocols and materials databases
DNASU	1462.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1462.
KEGG	hsa:1462.
Organism-specific databases
CTD	1462.
PharmGKB	PA162408788.
Phylogenomic databases
HOGENOM	HOG000168523.
HOVERGEN	HBG061970.
KO	K06793.
Gene expression databases
ArrayExpress	Q6MZK8.
Family and domain databases
Gene3D	3.10.100.10. 1 hit.
InterPro	IPR001304. C-type_lectin. IPR016186. C-type_lectin-like. IPR018378. C-type_lectin_CS. IPR016187. C-type_lectin_fold. IPR000742. EG-like_dom. IPR001881. EGF-like_Ca-bd. IPR013032. EGF-like_CS. IPR000152. EGF-type_Asp/Asn_hydroxyl_site. IPR018097. EGF_Ca-bd_CS. IPR000436. Sushi_SCR_CCP. [Graphical view]
Pfam	PF00008. EGF. 2 hits. PF00059. Lectin_C. 1 hit. PF00084. Sushi. 1 hit. [Graphical view]
SMART	SM00032. CCP. 1 hit. SM00034. CLECT. 1 hit. SM00181. EGF. 1 hit. SM00179. EGF_CA. 1 hit. [Graphical view]
SUPFAM	SSF56436. C-type_lectin_fold. 1 hit. SSF57535. Complement_control_module. 1 hit.
PROSITE	PS00010. ASX_HYDROXYL. 1 hit. PS00615. C_TYPE_LECTIN_1. 1 hit. PS50041. C_TYPE_LECTIN_2. 1 hit. PS00022. EGF_1. 2 hits. PS01186. EGF_2. 1 hit. PS50026. EGF_3. 2 hits. PS01187. EGF_CA. 1 hit. PS50923. SUSHI. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	1462.
NextBio	6005.

Entry information

Entry name

Q6MZK8_HUMAN

Accession

Primary (citable) accession number: Q6MZK8

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	March 6, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.