Q6MX34 (Q6MX34_MYCTU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
PROBABLE UROPORPHYRIN-III C-METHYLTRANSFERASE HEMD (UROPORPHYRINOGEN III METHYLASE) (UROGEN III METHYLASE) (SUMT) (UROGEN III METHYLASE) (UROM) EMBL CAE55293.1
EC=2.1.1.107 EMBL CAE55293.1

Gene names

Name:	hemD EMBL CAE55293.1
Ordered Locus Names:	Rv0511

Organism

Mycobacterium tuberculosis

Taxonomic identifier

1773 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	565 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Methyltransferase EMBL CAE55293.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	growth Inferred from mutant phenotype. Source: MTBBASE tetrapyrrole biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	plasma membrane Inferred from direct assay. Source: MTBBASE
Molecular function	uroporphyrin-III C-methyltransferase activity Inferred from electronic annotation. Source: EC uroporphyrinogen-III synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6MX34 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: BA1C3CF881713D9F	FASTA	565	58,836
	10 20 30 40 50 60 MTRGRKPRPG RIVFVGSGPG DPGLLTTRAA AVLANAALVF TDPDVPEPVV ALIGTDLPPV 70 80 90 100 110 120 SGPAPAEPVA GNGDAAGGGS AQEHGRAASA VVSGGPDIRP ALGDPADVAK TLTAEARSGV 130 140 150 160 170 180 DVVRLVAGDP LTVDAVISEV NAVARTHLHI EIVPGLAASS AVPTYAGLPL GSSHTVADVR 190 200 210 220 230 240 IDPENTDWDA LAAAPGPLIL QATASHLAES ARSLIDHQLA ESTPCVVTAH GTTCQQRSVE 250 260 270 280 290 300 TTLQGLTDPA VLGATDPACS ANGRDSQAGP LIVTIGKTVT SRAKLNWWES RALYGWTVLV 310 320 330 340 350 360 PRTKDQAGEM SERLTSYGAL PVEVPTIAVE PPRSPAQMER AVKGLVDGRF QWIVFTSTNA 370 380 390 400 410 420 VRAVWEKFGE FGLDARAFSG VKIACVGEST ADRVRAFGIS PELVPSGEQS SLGLLDDFPP 430 440 450 460 470 480 YDSVFDPVNR VLLPRADIAT ETLAEGLRER GWEIEDVTAY RTVRAAPPPA TTREMIKTGG 490 500 510 520 530 540 FDAVCFTSSS TVRNLVGIAG KPHARTIIAC IGPKTAETAA EFGLRVDVQP DTAAIGPLVD 550 560 ALAEHAARLR AEGALPPPRK KSRRR

References

[1]

"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. Nature 393:537-544(1998) [PubMed: 9634230] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25618 / H37Rv.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX842573 Genomic DNA. Translation: CAE55293.1.
RefSeq	YP_177733.1. NC_000962.2.
3D structure databases
ProteinModelPortal	Q6MX34.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000002071; EBMYCP00000002071; EBMYCG00000002069.
GeneID	887280.
GenomeReviews	Gene locus Rv0511 in contig AL123456_GR.
KEGG	mtu:Rv0511.
PATRIC	18149630. VBIMycTub87468_0567.
Organism-specific databases
TubercuList	Rv0511.
Phylogenomic databases
GeneTree	EBGT00050000016432.
HOGENOM	HBG730212.
OMA	ETREMIK.
PhylomeDB	Q6MX34.
ProtClustDB	CLSK799401.
Family and domain databases
InterPro	IPR000878. 4pyrrol_Mease. IPR003754. 4pyrrol_synth_uPrphyn_synth. IPR014777. 4pyrrole_Mease_sub1. IPR014776. 4pyrrole_Mease_sub2. [Graphical view]
Gene3D	G3DSA:3.40.1010.10. 4pyrrole_Mease_sub1. 2 hits. G3DSA:3.30.950.10. 4pyrrole_Mease_sub2. 1 hit.
KO	K13542.
Pfam	PF02602. HEM4. 1 hit. PF00590. TP_methylase. 1 hit. [Graphical view]
SUPFAM	SSF53790. Cor/por_Metransf. 1 hit. SSF69618. HEM4_synth. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q6MX34_MYCTU

Accession

Primary (citable) accession number: Q6MX34

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)