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Q6MU23 (Q6MU23_MYCMS) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase HAMAP MF_00163
Short name=PDF HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase HAMAP MF_00163
Gene names
Name:pdf EMBL CAE76863.1
Synonyms:def HAMAP MF_00163
Ordered Locus Names:MSC_0220
OrganismMycoplasma mycoides subsp. mycoides SC (strain PG1)
Taxonomic identifier272632 [NCBI]
Taxonomic lineageBacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length200 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163 RuleBase RU003335

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1711 By similarity HAMAP MF_00163
Metal binding1261Iron By similarity HAMAP MF_00163
Metal binding1701Iron By similarity HAMAP MF_00163
Metal binding1741Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
Q6MU23 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 91DF76C9C5D89E3D

FASTA20023,403
        10         20         30         40         50         60 
MDKSYLLQDK IPSNSWLVKD HKKEIIRTKS TKIIDPTNLS NNEELVLKKL IDFVTFSQDE 

        70         80         90        100        110        120 
NNNNINNKDY LRPAVGLAAP QIGVNKDMFY VRFQLDNNKI EQYAMINTKL ISTSTQIACL 

       130        140        150        160        170        180 
KNGEGCLSVD NYHLGFVPRH YKIVVQGYDW LTKQYLTLTL RNYQAIVFQH EMDHNIGVLY 

       190        200 
YDHINKTDPL YKNNNWIIIE

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References

[1]"The genome sequence of Mycoplasma mycoides subsp. mycoides SC type strain PG1T, the causative agent of contagious bovine pleuropneumonia (CBPP)."
Westberg J., Persson A., Holmberg A., Goesmann A., Lundeberg J., Johansson K.-E., Pettersson B., Uhlen M.
Genome Res. 14:221-227(2004) [PubMed: 14762060] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PG1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX293980 Genomic DNA. Translation: CAE76863.1.
RefSeqNP_975221.1. NC_005364.2.

3D structure databases

ProteinModelPortalQ6MU23.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2745251.
GenomeReviewsGene locus MSC_0220 in contig BX293980_GR.
KEGGmmy:MSC_0220.
PATRIC20017156. VBIMycMyc4973_0234.

Phylogenomic databases

HOGENOMHBG665227.
OMALKNGEGC.
PhylomeDBQ6MU23.
ProtClustDBCLSK745701.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
TIGRFAMsTIGR00079. Pept_deformyl. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ6MU23_MYCMS
AccessionPrimary (citable) accession number: Q6MU23
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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