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Protein

Signal recognition particle receptor FtsY

Gene

ftsY

Organism
Mycoplasma mycoides subsp. mycoides SC (strain PG1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi192 – 1998GTPUniRule annotation
Nucleotide bindingi278 – 2825GTPUniRule annotation
Nucleotide bindingi342 – 3454GTPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Receptor

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMMYC272632:GI1G-474-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Signal recognition particle receptor FtsYUniRule annotation
Short name:
SRP receptorUniRule annotation
Gene namesi
Name:ftsYUniRule annotation
Ordered Locus Names:MSC_0489
OrganismiMycoplasma mycoides subsp. mycoides SC (strain PG1)
Taxonomic identifieri272632 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000001016 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 400400Signal recognition particle receptor FtsYPRO_0000416703Add
BLAST

Interactioni

Subunit structurei

Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.UniRule annotation

Protein-protein interaction databases

STRINGi272632.MSC_0489.

Structurei

Secondary structure

1
400
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi92 – 10716Combined sources
Helixi114 – 12613Combined sources
Helixi131 – 14414Combined sources
Helixi151 – 16717Combined sources
Helixi173 – 1764Combined sources
Beta strandi186 – 1938Combined sources
Helixi198 – 21114Combined sources
Beta strandi216 – 2205Combined sources
Helixi226 – 23611Combined sources
Turni237 – 2393Combined sources
Beta strandi244 – 2474Combined sources
Helixi256 – 26914Combined sources
Beta strandi273 – 2786Combined sources
Helixi283 – 2853Combined sources
Helixi286 – 30116Combined sources
Beta strandi309 – 3168Combined sources
Helixi317 – 3204Combined sources
Helixi321 – 33010Combined sources
Turni331 – 3333Combined sources
Beta strandi338 – 3425Combined sources
Helixi344 – 3463Combined sources
Helixi352 – 3609Combined sources
Beta strandi364 – 3685Combined sources
Beta strandi370 – 3723Combined sources
Beta strandi376 – 3783Combined sources
Helixi381 – 3888Combined sources
Helixi390 – 3923Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1ZU4X-ray1.95A88-400[»]
1ZU5X-ray2.40A/B88-400[»]
ProteinModelPortaliQ6MTB9.
SMRiQ6MTB9. Positions 87-393.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ6MTB9.

Family & Domainsi

Sequence similaritiesi

Belongs to the GTP-binding SRP family. FtsY subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CCP. Bacteria.
COG0552. LUCA.
HOGENOMiHOG000036277.
KOiK03110.
OMAiGINDLQV.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00920. FtsY. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR027417. P-loop_NTPase.
IPR013822. Signal_recog_particl_SRP54_hlx.
IPR004390. SR_rcpt_FtsY.
IPR000897. SRP54_GTPase_dom.
[Graphical view]
PfamiPF00448. SRP54. 1 hit.
PF02881. SRP54_N. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00962. SRP54. 1 hit.
SM00963. SRP54_N. 1 hit.
[Graphical view]
SUPFAMiSSF47364. SSF47364. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00064. ftsY. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6MTB9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGFWAKLKEK LTKKTNQVEQ DEPILDQQDQ QDQQEEQEQI IEKEIEQIKE
60 70 80 90 100
NKIKKTKTSE TKKQEKPIET LKEKKKREKQ KEKDKKVEKA MLKSAFNFSK
110 120 130 140 150
DIKKLSKKYK QADDEFFEEL EDVLIQTDMG MKMVLKVSNL VRKKTKRDTS
160 170 180 190 200
FENIKDALVE SLYQAYTDND WTNKKYRIDF KENRLNIFML VGVNGTGKTT
210 220 230 240 250
SLAKMANYYA ELGYKVLIAA ADTFRAGATQ QLEEWIKTRL NNKVDLVKAN
260 270 280 290 300
KLNADPASVV FDAIKKAKEQ NYDLLLIDTA GRLQNKVNLM AELEKMNKII
310 320 330 340 350
QQVEKSAPHE VLLVIDATTG QNGVIQAEEF SKVADVSGII LTKMDSTSKG
360 370 380 390 400
GIGLAIKELL NIPIKMIGVG EKVDDLLAFD IDQYIVHLSS GFMQGDEVEK
Length:400
Mass (Da):45,730
Last modified:July 5, 2004 - v1
Checksum:iE8ABED8D9BD99CAD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX293980 Genomic DNA. Translation: CAE77117.1.
RefSeqiNP_975475.1. NC_005364.2.
WP_011166673.1. NC_005364.2.

Genome annotation databases

EnsemblBacteriaiCAE77117; CAE77117; MSC_0489.
GeneIDi2745026.
KEGGimmy:MSC_0489.
PATRICi20017757. VBIMycMyc4973_0529.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX293980 Genomic DNA. Translation: CAE77117.1.
RefSeqiNP_975475.1. NC_005364.2.
WP_011166673.1. NC_005364.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1ZU4X-ray1.95A88-400[»]
1ZU5X-ray2.40A/B88-400[»]
ProteinModelPortaliQ6MTB9.
SMRiQ6MTB9. Positions 87-393.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272632.MSC_0489.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAE77117; CAE77117; MSC_0489.
GeneIDi2745026.
KEGGimmy:MSC_0489.
PATRICi20017757. VBIMycMyc4973_0529.

Phylogenomic databases

eggNOGiENOG4105CCP. Bacteria.
COG0552. LUCA.
HOGENOMiHOG000036277.
KOiK03110.
OMAiGINDLQV.

Enzyme and pathway databases

BioCyciMMYC272632:GI1G-474-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ6MTB9.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00920. FtsY. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR027417. P-loop_NTPase.
IPR013822. Signal_recog_particl_SRP54_hlx.
IPR004390. SR_rcpt_FtsY.
IPR000897. SRP54_GTPase_dom.
[Graphical view]
PfamiPF00448. SRP54. 1 hit.
PF02881. SRP54_N. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00962. SRP54. 1 hit.
SM00963. SRP54_N. 1 hit.
[Graphical view]
SUPFAMiSSF47364. SSF47364. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00064. ftsY. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFTSY_MYCMS
AccessioniPrimary (citable) accession number: Q6MTB9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 18, 2012
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.