Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Arginine--tRNA ligase

Gene

argS

Organism
Mycoplasma mycoides subsp. mycoides SC (strain PG1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:MSC_0599
OrganismiMycoplasma mycoides subsp. mycoides SC (strain PG1)
Taxonomic identifieri272632 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000001016 Componenti: Chromosome

Subcellular locationi

Q6MT14:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002420511 – 554Arginine--tRNA ligaseAdd BLAST554

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi272632.MSC_0599.

Structurei

3D structure databases

ProteinModelPortaliQ6MT14.
SMRiQ6MT14.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi123 – 133"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107RUW. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247214.
KOiK01887.
OMAiNKPLHLG.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6MT14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTTIIEMFY NDLKNICQKL NITKEPIIEI NKNNTPGLLS SSICLISSKQ
60 70 80 90 100
VNKKPLELAE IFKQELLLTN SYLNIDIAAP GFLNVLVKPE ILSNVISNVL
110 120 130 140 150
SLKSKYGNLE KQNKTINIEY VSANPTGYLH VGHARNAVIG SVLVNLFKKA
160 170 180 190 200
GYNVQTEYYV NDAGNQINVL AVTVFVHYLQ ALNIDAKKPE NCYAGDMYDD
210 220 230 240 250
LAKIIINKYN YQFKDIKYTD NKILDYNVHS LFKQISIDYF LKVIKQQLAD
260 270 280 290 300
FNVKIKHWSS EQEVYDTHQI EKVLKLYESK DALYYKDDAL FLKTTQFGDD
310 320 330 340 350
KDRVLVKSDK TYTYILPDLA THNLRIKRTK ADKLINVWGG DHHGYIKRMQ
360 370 380 390 400
AGLALLGNDP DILEIQMVQM VRLIKDGSEY KMSKRKGTAV WLVDILELVG
410 420 430 440 450
VDALRYMLAS KSSNSHMDLD LDLITLKNSS NPVYYAQYAT ARCHSILNQA
460 470 480 490 500
RTKKITPLVK ETNLLNNPKE IELLLVLDNF KEVIKNSANN RSTQQICDYI
510 520 530 540 550
QNICKIFHSY YAEIKIIDEN NLQLTKLRLG FIKAVLQVLE NAFFIIGIQP

VLEM
Length:554
Mass (Da):63,407
Last modified:July 5, 2004 - v1
Checksum:iBB3C5401357D35DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX293980 Genomic DNA. Translation: CAE77222.1.
RefSeqiNP_975580.1. NC_005364.2.
WP_011166776.1. NC_005364.2.

Genome annotation databases

EnsemblBacteriaiCAE77222; CAE77222; MSC_0599.
GeneIDi2744697.
KEGGimmy:MSC_0599.
PATRICifig|272632.4.peg.644.

Similar proteinsi

Entry informationi

Entry nameiSYR_MYCMS
AccessioniPrimary (citable) accession number: Q6MT14
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 5, 2004
Last modified: October 25, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families