Reviewed, UniProtKB/Swiss-Prot Q6MQ03 (GCST_BDEBA)

Names and origin

Protein names

Recommended name:
    Aminomethyltransferase
    EC=2.1.2.10
Alternative name(s):
    Glycine cleavage system T protein

Gene names

Name:	gcvT
Ordered Locus Names:	Bd0684

Organism

Bdellovibrio bacteriovorus [Complete proteome] [HAMAP]

Taxonomic identifier

959 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Bdellovibrionales › Bdellovibrionaceae › Bdellovibrio

Protein attributes

Sequence length	360 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity.
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity.
Sequence similarities	Belongs to the gcvT family.

Ontologies

Keywords
Molecular function	Aminotransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 360	360	Aminomethyltransferase HAMAP MF_00259		PRO_0000122545

Sequences

	Sequence		Length	Mass (Da)
	Q6MQ03-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: BE9BA5A91B3044D2	FASTA	360	39,861
	10 20 30 40 50 60 MKKTPLADTH EKLGARMVDF AGWYMPVQYI GLREEHNNVR TNVGLFDVSH MGEVRVKGPK 70 80 90 100 110 120 ALETLEWLTT NDVSKLNDGE AQYSLLPNDQ GGLVDDIIVY CLSKDSDYLV CVNASNKDKD 130 140 150 160 170 180 FAWMTKHNKG ADITDESDLW GQIAIQGPKA LELCDRVFDI KVSEMKSFTV KSGTFKGHKI 190 200 210 220 230 240 MIATTGYTGE KGCEVFVEAA GTADLWMTLL EKGKDLGCMG IGLGARDTLR TEMKYSLYGH 250 260 270 280 290 300 EIDDTTNPYE AGLGWVIKPA KKDFMNKAQI VGKKEAGLTR NLVGFKMLEK GIPRQGYSLF 310 320 330 340 350 360 SFDNKEIGKV TSGTHSPTLD EPIGIAFIDV AYAKEGTEFL LDIRGRKVKA VVCKTPFVTK

References

[1]

"A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a genomic perspective." Rendulic S., Jagtap P., Rosinus A., Eppinger M., Baar C., Lanz C., Keller H., Lambert C., Evans K.J., Goesmann A., Meyer F., Sockett R.E., Schuster S.C. Science 303:689-692(2004) [PubMed: 14752164] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15356 / HD100 / DSM 50701 / NCIB 9529.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX842647 Genomic DNA. Translation: CAE78644.1.
RefSeq	NP_967651.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2734312.
GenomeReviews	Gene locus Bd0684 in contig BX842601_GR.
KEGG	bba:Bd0684.
NMPDR	fig|264462.1.peg.621.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q6MQ03.
OMA	VEIRGKW.
Enzyme and pathway databases
BioCyc	BBAC264462:BD0684-MON.
BRENDA	2.1.2.10. 3459.
Family and domain databases
HAMAP	MF_00259. [Tree]
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. [Graphical view]
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. gcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GCST_BDEBA

Accession

Primary (citable) accession number: Q6MQ03

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 15, 2005
Last sequence update:	July 5, 2004
Last modified:	November 3, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)