Q6MMX5 (Q6MMX5_BDEBA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid A disaccharide synthase EMBL CAE79378.1
EC=2.4.1.182 EMBL CAE79378.1

Gene names

Name:	lpxB EMBL CAE79378.1
Ordered Locus Names:	Bd1498

Organism

Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIB 9529 / HD100) [Complete proteome] [HAMAP]

Taxonomic identifier

264462 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Bdellovibrionales › Bdellovibrionaceae › Bdellovibrio

Protein attributes

Sequence length	382 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL CAE79378.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6MMX5 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: F1880543A37F352A	FASTA	382	43,764
	10 20 30 40 50 60 MDQVLIVAAE ASSVTYAQRI LEAWKAQGRK VHAFGVGSQD MEDIGFERLG KSEEMAVVGA 70 80 90 100 110 120 AEIISAYSHL KSVFDSLVAE AEKRRPKVAI VMDYPEFNLM LAKKLHALGI PVVYYISPQV 130 140 150 160 170 180 WAWRKGRVKT IKKYCKKVFV LFPFEVPFYE EHGVPVEFVG HPLLDELDER LIDDLEYRKN 190 200 210 220 230 240 HRNQCGIRDS EIVLGLMPGS RRLEVKQHLD IQLDAARILS KKFPNLKVLI LTAPTFTKEY 250 260 270 280 290 300 MQDRLENFRL PYMLLKDEPF RMIHLVDMML VASGTATLQV GLLKKPMVIM YKMKWLTGVF 310 320 330 340 350 360 AKLFVRGTKY FGLVNLILNK EAVPELFQSE VTAENLAAEL ERYVLDKKYH DSVVSDLGQV 370 380 RQYLGDKGAT QRVVKALEEY FV

References

[1]

"A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a genomic perspective." Rendulic S., Jagtap P., Rosinus A., Eppinger M., Baar C., Lanz C., Keller H., Lambert C., Evans K.J., Goesmann A., Meyer F., Sockett R.E., Schuster S.C. Science 303:689-692(2004) [PubMed: 14752164] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15356 / DSM 50701 / NCIB 9529 / HD100.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX842650 Genomic DNA. Translation: CAE79378.1.
RefSeq	NP_968385.1. NC_005363.1.
3D structure databases
ProteinModelPortal	Q6MMX5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2735567.
GenomeReviews	Gene locus Bd1498 in contig BX842601_GR.
KEGG	bba:Bd1498.
NMPDR	fig|264462.1.peg.1355.
PATRIC	21077550. VBIBdeBac73187_1352.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG584837.
OMA	AEFAFIC.
PhylomeDB	Q6MMX5.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q6MMX5_BDEBA

Accession

Primary (citable) accession number: Q6MMX5

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)