ID   Q6MKW1_BDEBA            Unreviewed;       467 AA.
AC   Q6MKW1;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 109.
DE   RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN   Name=aldH {ECO:0000313|EMBL:CAE80096.1};
GN   OrderedLocusNames=Bd2266 {ECO:0000313|EMBL:CAE80096.1};
OS   Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 /
OS   HD100).
OC   Bacteria; Bdellovibrionota; Bdellovibrionia; Bdellovibrionales;
OC   Pseudobdellovibrionaceae; Bdellovibrio.
OX   NCBI_TaxID=264462 {ECO:0000313|EMBL:CAE80096.1, ECO:0000313|Proteomes:UP000008080};
RN   [1] {ECO:0000313|EMBL:CAE80096.1, ECO:0000313|Proteomes:UP000008080}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
RC   {ECO:0000313|Proteomes:UP000008080};
RX   PubMed=14752164; DOI=10.1126/science.1093027;
RA   Rendulic S., Jagtap P., Rosinus A., Eppinger M., Baar C., Lanz C.,
RA   Keller H., Lambert C., Evans K.J., Goesmann A., Meyer F., Sockett R.E.,
RA   Schuster S.C.;
RT   "A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a
RT   genomic perspective.";
RL   Science 303:689-692(2004).
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC       ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; BX842652; CAE80096.1; -; Genomic_DNA.
DR   RefSeq; WP_011164698.1; NC_005363.1.
DR   AlphaFoldDB; Q6MKW1; -.
DR   STRING; 264462.Bd2266; -.
DR   KEGG; bba:Bd2266; -.
DR   eggNOG; COG1012; Bacteria.
DR   HOGENOM; CLU_005391_3_1_7; -.
DR   Proteomes; UP000008080; Chromosome.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR   CDD; cd07134; ALDH_AlkH-like; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR   PANTHER; PTHR43570; ALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR43570:SF16; ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   PIRSF; PIRSF036492; ALDH; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|PIRNR:PIRNR036492};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008080}.
FT   DOMAIN          20..434
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        208
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU10007"
FT   ACT_SITE        242
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ   SEQUENCE   467 AA;  52410 MW;  C3742A4357D93493 CRC64;
     MLERIFLHQK QFALKLRGES LDVRIEALEA LEKSIELHKQ DIIDALKKDF QKPEAETLLS
     EIYPVLKEIT YAKKNLSRWA KGRRVPTPLT LFGSKSYIVP EARGVCLLIA PWNYPFQLAF
     SPLVSAIASG NCAIMKPSEQ TRHTSSIIKK ITTEAFHPDH VFVAEGGPET TQELLSFAFD
     HIFFTGSTRV GKIVMTAAAK NLASVTLELG GKSPTIVDAT ANLAEAAEKI AWAKFINAGQ
     TCVAPDYLFV HESVQHNFKK HLIAALEKFY GKSAEQRKQS PDFARMISFN HSQRLKDLID
     EAVSKNAKVF FGGESQPEEH YCGPTLIEGV DPHSLIMQEE IFGPILPVMT FKEISEVIHF
     INERPKPLAL YCYTHSQMNM EKIEKETSSG GLVYNDSVIH FANPHLPFGG VNHSGMGSYH
     GKHGFLEFSH QKAVLKQSFL GKLLRVMYPP YTEFKMTALK NLIRFSL
//