Reviewed, UniProtKB/Swiss-Prot Q6MJR8 (NTPA_BDEBA)

Names and origin

Protein names

Recommended name:
    Nucleoside-triphosphatase
    EC=3.6.1.15
Alternative name(s):
    Nucleoside triphosphate phosphohydrolase
      Short name=NTPase

Gene names

Ordered Locus Names:

Bd2701

Organism

Bdellovibrio bacteriovorus [Complete proteome] [HAMAP]

Taxonomic identifier

959 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Bdellovibrionales › Bdellovibrionaceae › Bdellovibrio

Protein attributes

Sequence length	199 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions By similarity.
Catalytic activity	NTP + H2O = NDP + phosphate. HAMAP MF_01405
Cofactor	Divalent cations By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the HAM1 NTPase family.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	nucleoside-triphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 199	199	Nucleoside-triphosphatase HAMAP MF_01405		PRO_0000178133

Sequences

	Sequence		Length	Mass (Da)
	Q6MJR8-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: C14A4D6E3718DE2E	FASTA	199	21,763
	10 20 30 40 50 60 MELWIATGNK GKLAEYKQLL RELPDLKVFS QGDIASFTPR PEDGKTFEDN ARIKAKTLRA 70 80 90 100 110 120 VKNNVWVLGE DAGLVVEGLN GLPGIHSARY AGPKASDSEN VSKLLKMITL RPMPNKNAKF 130 140 150 160 170 180 VCTTVVYTPT GEEWVFNGEM KGTIASKPAG LHGFGYDPVF IPEGQTQTLA ELGTGYKSLL 190 SHRAMALKAF LEKLQTVNP

References

[1]

"A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a genomic perspective." Rendulic S., Jagtap P., Rosinus A., Eppinger M., Baar C., Lanz C., Keller H., Lambert C., Evans K.J., Goesmann A., Meyer F., Sockett R.E., Schuster S.C. Science 303:689-692(2004) [PubMed: 14752164] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15356 / HD100 / DSM 50701 / NCIB 9529.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX842653 Genomic DNA. Translation: CAE80492.1.
RefSeq	NP_969499.1.
3D structure databases
HSSP	HSSP built from PDB template 1K7K based on UniProtKB P52061.
ModBase	Search...
Genome annotation databases
GeneID	2736218.
GenomeReviews	Gene locus Bd2701 in contig BX842601_GR.
KEGG	bba:Bd2701.
NMPDR	fig|264462.1.peg.2471.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q6MJR8.
OMA	Q6MJR8. VYTADWA.
Enzyme and pathway databases
BioCyc	BBAC264462:BD2701-MON.
BRENDA	3.6.1.15. 3459.
Family and domain databases
HAMAP	MF_01405. [Tree]
InterPro	IPR002637. Ham1p-like. [Graphical view]
PANTHER	PTHR11067. Ham1p_like. 1 hit.
Pfam	PF01725. Ham1p_like. 1 hit. [Graphical view]
TIGRFAMs	TIGR00042. Ham1p_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NTPA_BDEBA

Accession

Primary (citable) accession number: Q6MJR8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 26, 2005
Last sequence update:	July 5, 2004
Last modified:	June 16, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)