ID   Q6MIS6_BDEBA            Unreviewed;       480 AA.
AC   Q6MIS6;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 84.
DE   SubName: Full=Probable adenylate cyclase {ECO:0000313|EMBL:CAE80837.1};
DE            EC=4.6.1.1 {ECO:0000313|EMBL:CAE80837.1};
GN   Name=cyaC {ECO:0000313|EMBL:CAE80837.1};
GN   OrderedLocusNames=Bd3072 {ECO:0000313|EMBL:CAE80837.1};
OS   Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 /
OS   HD100).
OC   Bacteria; Bdellovibrionota; Bdellovibrionia; Bdellovibrionales;
OC   Pseudobdellovibrionaceae; Bdellovibrio.
OX   NCBI_TaxID=264462 {ECO:0000313|EMBL:CAE80837.1, ECO:0000313|Proteomes:UP000008080};
RN   [1] {ECO:0000313|EMBL:CAE80837.1, ECO:0000313|Proteomes:UP000008080}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100
RC   {ECO:0000313|Proteomes:UP000008080};
RX   PubMed=14752164; DOI=10.1126/science.1093027;
RA   Rendulic S., Jagtap P., Rosinus A., Eppinger M., Baar C., Lanz C.,
RA   Keller H., Lambert C., Evans K.J., Goesmann A., Meyer F., Sockett R.E.,
RA   Schuster S.C.;
RT   "A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a
RT   genomic perspective.";
RL   Science 303:689-692(2004).
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DR   EMBL; BX842654; CAE80837.1; -; Genomic_DNA.
DR   RefSeq; WP_011165441.1; NC_005363.1.
DR   AlphaFoldDB; Q6MIS6; -.
DR   STRING; 264462.Bd3072; -.
DR   KEGG; bba:Bd3072; -.
DR   eggNOG; COG2114; Bacteria.
DR   HOGENOM; CLU_564596_0_0_7; -.
DR   Proteomes; UP000008080; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:CAE80837.1}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008080};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        27..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        124..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        157..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          248..381
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   480 AA;  54269 MW;  47731BBEB0EAA4C8 CRC64;
     MLGKEITTSQ MREFEVVEEI RSVLRVIANW MAVPLFMAFW ISDLIYVPQF KWLFLGLRLT
     IIPLCMLAKY ELRKEQSFTR AQWFAALYAG LVALPINIMI YFIPDVGTGY YAGLNLVAIG
     GLSFIPFSTG FFVATALGIY LPYYLFTALK IQTLPDLWPV VLNSFFIIGS IVICFLIRFF
     HEQLRMREIN SRLALKAEIA NRDHIIKSKT EEAVRLNTLS TQFSPQVVQA IREGKVDLEK
     GVRRAQICAI FVDIVGSTER VVRLDQAKVD LVLARFMDTV VSIFLKYDIT IDKFQGDGIL
     AFANDPIRYG DYTQRTCLAA LEVREALRQD REFYLMNWKK EMQIRIGISA GYANVGFYGN
     KKFFRSYTAI GAPLPFASRL TNLAEPDQIL IDSDIAQTLQ SEGFAVKNIG ERVIKGFEGD
     THYVFELNQA PVVRKDVSAS SCPHCPDSIL YLDTNAQGHF VMKCRACGYE AAEAQAVGAL
//