Q6MII5 (PPNK_BDEBA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable inorganic polyphosphate/ATP-NAD kinase
Short name=Poly(P)/ATP NAD kinase
EC=2.7.1.23

Gene names

Name:	ppnK
Ordered Locus Names:	Bd3172

Organism

Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIB 9529 / HD100) [Complete proteome] [HAMAP]

Taxonomic identifier

264462 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Bdellovibrionales › Bdellovibrionaceae › Bdellovibrio

Protein attributes

Sequence length	303 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity. HAMAP MF_00361
Subcellular location	Cytoplasm By similarity HAMAP MF_00361.
Sequence similarities	Belongs to the NAD kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding NAD NADP Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 303	303	Probable inorganic polyphosphate/ATP-NAD kinase HAMAP MF_00361		PRO_0000229610

Sequences

	Sequence		Length	Mass (Da)
	Q6MII5 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 4DBF66BB2D940451	FASTA	303	33,807
	10 20 30 40 50 60 MKKSSMDKEH KQSKLVLKEN GSIGLVYRLE TAQAVSLAKK VAEFLKERGF EVFTCPDQKV 70 80 90 100 110 120 VAGTKAAKTK KHMDDLKLVI VLGGDGTYLR AVRLLEGRSV PILGFNMGSL GFLTAHSADS 130 140 150 160 170 180 CFDIIEKTLE GKMVQRPRSM IYSKILRKGK VRAEYHALND MVIERGSMSQ LINTAIYSEK 190 200 210 220 230 240 FLVSQVKADG FIVASPSGST AYNLAAGGPI CHPESPVFVV TPVAPHSLTS RPLLFPDDRE 250 260 270 280 290 300 LSFRLEGKTQ KAHFIVDGQK MTELTADDEV IVSRSCYDHW MVREANHNYF HLLREKLKFG DRN

References

[1]

"A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a genomic perspective." Rendulic S., Jagtap P., Rosinus A., Eppinger M., Baar C., Lanz C., Keller H., Lambert C., Evans K.J., Goesmann A., Meyer F., Sockett R.E., Schuster S.C. Science 303:689-692(2004) [PubMed: 14752164] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15356 / DSM 50701 / NCIB 9529 / HD100.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX842654 Genomic DNA. Translation: CAE80928.1.
RefSeq	NP_969935.1. NC_005363.1.
3D structure databases
ProteinModelPortal	Q6MII5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2736781.
GenomeReviews	Gene locus Bd3172 in contig BX842601_GR.
KEGG	bba:Bd3172.
NMPDR	fig|264462.1.peg.2908.
PATRIC	21080694. VBIBdeBac73187_2902.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG713904.
OMA	LLHLKNY.
PhylomeDB	Q6MII5.
Enzyme and pathway databases
BioCyc	BBAC264462:BD3172-MONOMER.
Family and domain databases
HAMAP	MF_00361. NAD_kinase. [Tree]
InterPro	IPR016064. ATP-NAD_kinase_PpnK-typ. IPR017438. ATP-NAD_kinase_PpnK-typ_a/b. IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. polyP/ATP_NADK_prd. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit. G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KO	K00858.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
SUPFAM	SSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PPNK_BDEBA

Accession

Primary (citable) accession number: Q6MII5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program