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Q6MIF7 (MRAY_BDEBA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phospho-N-acetylmuramoyl-pentapeptide-transferase
EC=2.7.8.13
Alternative name(s):
UDP-MurNAc-pentapeptide phosphotransferase
Gene names
Name:mraY
Ordered Locus Names:Bd3201
OrganismBdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIB 9529 / HD100) [Complete proteome] [HAMAP]
Taxonomic identifier264462 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Bdellovibrionales › Bdellovibrionaceae › Bdellovibrio

Protein attributes

Sequence length358 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan By similarity. HAMAP MF_00038

Catalytic activity

UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP MF_00038

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00038

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP MF_00038.

Sequence similarities

Belongs to the glycosyltransferase 4 family. MraY subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 358358Phospho-N-acetylmuramoyl-pentapeptide-transferase HAMAP MF_00038
PRO_0000108787

Regions

Transmembrane26 – 4621Helical; Potential
Transmembrane71 – 9121Helical; Potential
Transmembrane93 – 11321Helical; Potential
Transmembrane138 – 15821Helical; Potential
Transmembrane166 – 18621Helical; Potential
Transmembrane197 – 21721Helical; Potential
Transmembrane234 – 25421Helical; Potential
Transmembrane261 – 28121Helical; Potential
Transmembrane287 – 30721Helical; Potential
Transmembrane335 – 35521Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q6MIF7 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: A5319FC6C565CFE7

FASTA35839,064
        10         20         30         40         50         60 
MLYQWLYSMA DEFSPLNVFR YITVRTFIAF FTAFLLCWIW GPHFIKRLQL KHFGQAIRDD 

        70         80         90        100        110        120 
GPQTHKKKAG TPTMGGGLIL LSTLIPCLLW VDMMNPLVWG VLIVTWGFGL IGYMDDWLKV 

       130        140        150        160        170        180 
SKKNSKGLSG KIRLAGEFLI SGLVVAALVH FHGLSTAVTI PFMKSVSIDL GYFYVIFAAL 

       190        200        210        220        230        240 
VVVGTANAVN LTDGLDGLAI VPVMISAATL GLFAYVTGHF SIANYLQIPH VVGAGELSIV 

       250        260        270        280        290        300 
AATIVAAGMG FLWFNAYPAQ VFMGDVGSLS LGGFLGSMAV ITQNELLMLV LGGVFVVEAL 

       310        320        330        340        350 
SVITQVISFK MTGKRVFKMA PIHHHFELGG LTETKIIVRF WIISILLAVL SLATLKLR

« Hide

References

[1]"A predator unmasked: life cycle of Bdellovibrio bacteriovorus from a genomic perspective."
Rendulic S., Jagtap P., Rosinus A., Eppinger M., Baar C., Lanz C., Keller H., Lambert C., Evans K.J., Goesmann A., Meyer F., Sockett R.E., Schuster S.C.
Science 303:689-692(2004) [PubMed: 14752164] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15356 / DSM 50701 / NCIB 9529 / HD100.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX842654 Genomic DNA. Translation: CAE80956.1.
RefSeqNP_969963.1. NC_005363.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2736818.
GenomeReviewsGene locus Bd3201 in contig BX842601_GR.
KEGGbba:Bd3201.
NMPDRfig|264462.1.peg.2936.
PATRIC21080750. VBIBdeBac73187_2930.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG708263.
OMAGMISKTT.
PhylomeDBQ6MIF7.

Enzyme and pathway databases

BioCycBBAC264462:BD3201-MONOMER.

Family and domain databases

HAMAPMF_00038. MraY.
[Tree]
InterProIPR000715. Glycosyl_transferase_4.
IPR003524. PNAcMuramoyl-5peptid_Trfase.
IPR018480. PNAcMuramoyl-5peptid_Trfase_CS.
[Graphical view]
KOK01000.
PANTHERPTHR22926. Glyco_trans_4. 1 hit.
PTHR22926:SF3. PNAcPpept_trans. 1 hit.
PfamPF00953. Glycos_transf_4. 1 hit.
[Graphical view]
TIGRFAMsTIGR00445. MraY. 1 hit.
PROSITEPS01347. MRAY_1. False negative.
PS01348. MRAY_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMRAY_BDEBA
AccessionPrimary (citable) accession number: Q6MIF7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: July 5, 2004
Last modified: January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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