Q6MG48 (PRC2A_RAT) Reviewed, UniProtKB/Swiss-Prot
Last modified
April 3, 2013.
Version 65.
History...
Clusters with 
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Protein PRRC2A Alternative name(s): HLA-B-associated transcript 2 Proline-rich and coiled-coil-containing protein 2A | ||||
| Gene names |
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| Organism | Rattus norvegicus (Rat) [Reference proteome] | ||||
| Taxonomic identifier | 10116 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus |
Protein attributes
| Sequence length | 2161 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm Nucleus |
| Domain | Repeat |
| PTM | Acetylation Phosphoprotein |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Cellular_component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell nucleusInferred from electronic annotation. Source: UniProtKB-SubCell |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 2161 | 2161 | Protein PRRC2A | PRO_0000064832 | |||||
Regions | |||||||||
| Repeat | 41 – 95 | 55 | 1-1 | ||||||
| Repeat | 98 – 154 | 57 | 1-2 | ||||||
| Repeat | 281 – 337 | 57 | 1-3 | ||||||
| Repeat | 337 – 429 | 93 | 2-1 | ||||||
| Repeat | 487 – 560 | 74 | 2-2 | ||||||
| Repeat | 1760 – 1815 | 56 | 1-4 | ||||||
| Repeat | 1920 – 1969 | 50 | 3-1 | ||||||
| Repeat | 1986 – 2035 | 50 | 3-2 | ||||||
| Repeat | 2061 – 2110 | 50 | 3-3 | ||||||
| Region | 41 – 1815 | 1775 | 4 X 57 AA type A repeats | ||||||
| Region | 337 – 560 | 224 | 2 X type B repeats | ||||||
| Region | 1920 – 2110 | 191 | 3 X 50 AA type C repeats | ||||||
| Compositional bias | 404 – 414 | 11 | Poly-Pro | ||||||
| Compositional bias | 465 – 470 | 6 | Poly-Arg | ||||||
| Compositional bias | 471 – 474 | 4 | Poly-Glu | ||||||
| Compositional bias | 657 – 670 | 14 | Poly-Gln | ||||||
| Compositional bias | 697 – 701 | 5 | Poly-Pro | ||||||
| Compositional bias | 827 – 834 | 8 | Poly-Pro | ||||||
| Compositional bias | 909 – 916 | 8 | Poly-Gly | ||||||
| Compositional bias | 917 – 920 | 4 | Poly-Pro | ||||||
| Compositional bias | 959 – 962 | 4 | Poly-Pro | ||||||
| Compositional bias | 1239 – 1244 | 6 | Poly-Arg | ||||||
| Compositional bias | 1297 – 1300 | 4 | Poly-Pro | ||||||
| Compositional bias | 1407 – 1410 | 4 | Poly-Gly | ||||||
| Compositional bias | 1413 – 1421 | 9 | Poly-Gly | ||||||
| Compositional bias | 1451 – 1457 | 7 | Poly-Pro | ||||||
Amino acid modifications | |||||||||
| Modified residue | 27 | 1 | N6-acetyllysine By similarity | ||||||
| Modified residue | 166 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 342 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 350 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 378 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 381 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 455 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 609 | 1 | Phosphothreonine By similarity | ||||||
| Modified residue | 760 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 762 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 765 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 783 | 1 | Phosphothreonine By similarity | ||||||
| Modified residue | 809 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 1007 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 1017 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 1088 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 1092 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 1095 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 1097 | 1 | Phosphotyrosine By similarity | ||||||
| Modified residue | 1113 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 1150 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 1199 | 1 | N6-acetyllysine By similarity | ||||||
| Modified residue | 1222 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 1307 | 1 | Phosphoserine By similarity | ||||||
| Modified residue | 1354 | 1 | Phosphothreonine Ref.2 | ||||||
| Modified residue | 1368 | 1 | Phosphothreonine Ref.2 | ||||||
| Modified residue | 2117 | 1 | Phosphoserine By similarity | ||||||
Sequences
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References
| [1] | "The genomic sequence and comparative analysis of the rat major histocompatibility complex." Hurt P., Walter L., Sudbrak R., Klages S., Mueller I., Shiina T., Inoko H., Lehrach H., Guenther E., Reinhardt R., Himmelbauer H. Genome Res. 14:631-639(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Brown Norway. |
| [2] | "Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites." Hoffert J.D., Pisitkun T., Wang G., Shen R.-F., Knepper M.A. Proc. Natl. Acad. Sci. U.S.A. 103:7159-7164(2006) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1354 AND THR-1368, MASS SPECTROMETRY. Tissue: Renal collecting duct. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BX883046 Genomic DNA. Translation: CAE83998.1. |
| IPI | IPI00417730. |
| RefSeq | NP_997627.1. NM_212462.2. |
| UniGene | Rn.34262. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 10116.ENSRNOP00000001133. |
PTM databases | |
| PhosphoSite | Q6MG48. |
Proteomic databases | |
| PaxDb | Q6MG48. |
| PRIDE | Q6MG48. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| Ensembl | ENSRNOT00000001133; ENSRNOP00000001133; ENSRNOG00000000852. |
| GeneID | 294250. |
| KEGG | rno:294250. |
| UCSC | RGD:1303025. rat. |
Organism-specific databases | |
| CTD | 7916. |
| RGD | 1303025. Prrc2a. |
Phylogenomic databases | |
| eggNOG | NOG40021. |
| GeneTree | ENSGT00530000063496. |
| HOVERGEN | HBG004820. |
| InParanoid | Q6MG48. |
| OrthoDB | EOG4G7BXH. |
Gene expression databases | |
| ArrayExpress | Q6MG48. |
| Genevestigator | Q6MG48. |
| GermOnline | ENSRNOG00000000852. Rattus norvegicus. |
Family and domain databases | |
| InterPro | IPR009738. BAT2_N. [Graphical view] |
| Pfam | PF07001. BAT2_N. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 637822. |
Entry information
| Entry name | PRC2A_RAT | ||||||||
| Accession | Primary (citable) accession number: Q6MG48 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Chordata Protein Annotation Program | ||||||||