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Q6MG18

- Q6MG18_RAT

UniProt

Q6MG18 - Q6MG18_RAT

Protein
Submitted name:

Immediate early response 3

Gene

Ier3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi
  1. Functioni

    GO - Biological processi

    1. intrinsic apoptotic signaling pathway in response to DNA damage Source: Ensembl
    2. mitotic G2 DNA damage checkpoint Source: Ensembl
    3. negative regulation of apoptotic process Source: InterPro
    4. negative regulation of glycolytic process Source: Ensembl
    5. negative regulation of inflammatory response Source: Ensembl
    6. negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway Source: Ensembl
    7. negative regulation of systemic arterial blood pressure Source: Ensembl
    8. positive regulation of protein catabolic process Source: Ensembl
    9. regulation of DNA repair Source: Ensembl
    10. regulation of nucleocytoplasmic transport Source: Ensembl
    11. regulation of reactive oxygen species metabolic process Source: Ensembl
    12. response to protozoan Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Immediate early response 3Imported
    Submitted name:
    Immediate early response 3, isoform CRA_aImported
    Submitted name:
    Protein Ier3Imported
    Gene namesi
    Name:Ier3Imported
    Synonyms:2310ex4-5Imported, 2331ex4-5Imported, 2361ex4-5Imported, Flot1Imported, Gnl1Imported, Kiaa1949Imported, Rpl41-psImported, Rps2-ps1Imported, Rps2-ps2Imported, RT1-O2Imported, RT1-O3Imported, RT1-S2Imported, RT1-S3Imported, RT1-T24-1Imported, RT1-T24-2Imported, Tubb5Imported
    ORF Names:rCG_41772Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 20

    Organism-specific databases

    RGDi1303321. Ier3.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: Ensembl

    Expressioni

    Gene expression databases

    GenevestigatoriQ6MG18.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00390000003213.
    HOVERGENiHBG000172.
    InParanoidiQ6MG18.
    OMAiMCHSRSS.
    OrthoDBiEOG7Q5HG8.
    TreeFamiTF338252.

    Family and domain databases

    InterProiIPR024829. IEX-1.
    [Graphical view]
    PANTHERiPTHR16915. PTHR16915. 1 hit.
    PRINTSiPR02100. GENEIEX1.

    Sequencei

    Sequence statusi: Complete.

    Q6MG18-1 [UniParc]FASTAAdd to Basket

    « Hide

    MCHSRNHLHT MTGLRAPAPA PSTSPELRRG SGPEIFTFDP LPERAVASAV    50
    RPNTSRGHRK RSRRVLYPRV VRRQLPTEEP NIAKRILFLL LAIIFCQILM 100
    AEEGVSQALA PEDATSAISP EPISVPITAP PVLEPLNLTS ESSDYALDLK 150
    AFLQQHPAAF 160
    Length:160
    Mass (Da):17,605
    Last modified:July 5, 2004 - v1
    Checksum:i69867C812D6FA93C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06099824 Genomic DNA. No translation available.
    BX883048 Genomic DNA. Translation: CAE84029.1.
    CH474118 Genomic DNA. Translation: EDL86742.1.
    CH474118 Genomic DNA. Translation: EDL86743.1.
    RefSeqiNP_997670.1. NM_212505.2.
    UniGeneiRn.23638.

    Genome annotation databases

    EnsembliENSRNOT00000001099; ENSRNOP00000001099; ENSRNOG00000000827.
    GeneIDi294235.
    KEGGirno:294235.
    UCSCiRGD:1303321. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06099824 Genomic DNA. No translation available.
    BX883048 Genomic DNA. Translation: CAE84029.1 .
    CH474118 Genomic DNA. Translation: EDL86742.1 .
    CH474118 Genomic DNA. Translation: EDL86743.1 .
    RefSeqi NP_997670.1. NM_212505.2.
    UniGenei Rn.23638.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000001099 ; ENSRNOP00000001099 ; ENSRNOG00000000827 .
    GeneIDi 294235.
    KEGGi rno:294235.
    UCSCi RGD:1303321. rat.

    Organism-specific databases

    CTDi 8870.
    RGDi 1303321. Ier3.

    Phylogenomic databases

    GeneTreei ENSGT00390000003213.
    HOVERGENi HBG000172.
    InParanoidi Q6MG18.
    OMAi MCHSRSS.
    OrthoDBi EOG7Q5HG8.
    TreeFami TF338252.

    Miscellaneous databases

    NextBioi 637803.
    PROi Q6MG18.

    Gene expression databases

    Genevestigatori Q6MG18.

    Family and domain databases

    InterProi IPR024829. IEX-1.
    [Graphical view ]
    PANTHERi PTHR16915. PTHR16915. 1 hit.
    PRINTSi PR02100. GENEIEX1.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Brown NorwayImported.
    2. Shiina T., Inoko H.
      Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Brown NorwayImported.
    3. "The genomic sequence and comparative analysis of the rat major histocompatibility complex."
      Hurt P., Walter L., Sudbrak R., Klages S., Mueller I., Shiina T., Inoko H., Lehrach H., Guenther E., Reinhardt R., Himmelbauer H.
      Genome Res. 14:631-639(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Brown NorwayImported.
    4. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    5. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    7. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiQ6MG18_RAT
    AccessioniPrimary (citable) accession number: Q6MG18
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3