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Protein

Nurim

Gene

Nrm

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Nurim
Alternative name(s):
Nuclear envelope membrane protein
Nuclear rim protein
Gene namesi
Name:Nrm
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 20

Organism-specific databases

RGDi1302966 Nrm

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 4NuclearSequence analysis4
Transmembranei5 – 28HelicalSequence analysisAdd BLAST24
Topological domaini29 – 58Perinuclear spaceSequence analysisAdd BLAST30
Transmembranei59 – 80HelicalSequence analysisAdd BLAST22
Topological domaini81 – 97NuclearSequence analysisAdd BLAST17
Transmembranei98 – 114HelicalSequence analysisAdd BLAST17
Topological domaini115 – 133Perinuclear spaceSequence analysisAdd BLAST19
Transmembranei134 – 164HelicalSequence analysisAdd BLAST31
Topological domaini165 – 191NuclearSequence analysisAdd BLAST27
Transmembranei192 – 210HelicalSequence analysisAdd BLAST19
Topological domaini211 – 216Perinuclear spaceSequence analysis6
Transmembranei217 – 234HelicalSequence analysisAdd BLAST18
Topological domaini235 – 262NuclearSequence analysisAdd BLAST28

Keywords - Cellular componenti

Membrane, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002994001 – 262NurimAdd BLAST262

Proteomic databases

PaxDbiQ6MG14

Expressioni

Gene expression databases

BgeeiENSRNOG00000000818
ExpressionAtlasiQ6MG14 baseline and differential
GenevisibleiQ6MG14 RN

Interactioni

Protein-protein interaction databases

BioGridi262960, 1 interactor
STRINGi10116.ENSRNOP00000001085

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi67 – 72Poly-Leu6
Compositional biasi139 – 253Leu-richAdd BLAST115

Sequence similaritiesi

Belongs to the nurim family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IVGT Eukaryota
ENOG4111VYI LUCA
GeneTreeiENSGT00390000008146
HOGENOMiHOG000039993
HOVERGENiHBG102998
InParanoidiQ6MG14
OMAiHPLMLGF
OrthoDBiEOG091G0MZT
PhylomeDBiQ6MG14
TreeFamiTF324853

Family and domain databases

InterProiView protein in InterPro
IPR033580 Nurim-like
PANTHERiPTHR31040 PTHR31040, 1 hit

Sequencei

Sequence statusi: Complete.

Q6MG14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPALLLVPA ALASFVLAFG TGVEFVRFTS LRPLLGGIPE SGGPDARHGW
60 70 80 90 100
LAALQDRSIL ASLAWDLCLL LLFVVQHSLM ATEAVKAWTS RYFGVLQRSL
110 120 130 140 150
YVACTALALQ LVMRYWEATP RGPVLWEARA EPWATWVPLL CFVLHVVSWL
160 170 180 190 200
LIFSILLVFD YAELMGLKQV YYHVLGLGEP LSLKSPRALR LFSHLRHPVC
210 220 230 240 250
VELLTVLWVV PTLGTDRLLL ALLFTLYLGL AHGLDQQDLR YLRSQLQRKL
260
QLLSRPQDGE AE
Length:262
Mass (Da):29,382
Last modified:July 5, 2004 - v1
Checksum:iFEAC40DA59359772
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX883048 Genomic DNA Translation: CAE84033.1
RefSeqiNP_997673.1, NM_212508.2
UniGeneiRn.38521

Genome annotation databases

EnsembliENSRNOT00000001085; ENSRNOP00000001085; ENSRNOG00000000818
GeneIDi361791
KEGGirno:361791
UCSCiRGD:1302966 rat

Similar proteinsi

Entry informationi

Entry nameiNRM_RAT
AccessioniPrimary (citable) accession number: Q6MG14
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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