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Q6MG14

- NRM_RAT

UniProt

Q6MG14 - NRM_RAT

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Protein

Nurim

Gene

Nrm

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Nurim
Alternative name(s):
Nuclear envelope membrane protein
Nuclear rim protein
Gene namesi
Name:Nrm
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 20

Organism-specific databases

RGDi1302966. Nrm.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 44NuclearSequence Analysis
Transmembranei5 – 2824HelicalSequence AnalysisAdd
BLAST
Topological domaini29 – 5830Perinuclear spaceSequence AnalysisAdd
BLAST
Transmembranei59 – 8022HelicalSequence AnalysisAdd
BLAST
Topological domaini81 – 9717NuclearSequence AnalysisAdd
BLAST
Transmembranei98 – 11417HelicalSequence AnalysisAdd
BLAST
Topological domaini115 – 13319Perinuclear spaceSequence AnalysisAdd
BLAST
Transmembranei134 – 16431HelicalSequence AnalysisAdd
BLAST
Topological domaini165 – 19127NuclearSequence AnalysisAdd
BLAST
Transmembranei192 – 21019HelicalSequence AnalysisAdd
BLAST
Topological domaini211 – 2166Perinuclear spaceSequence Analysis
Transmembranei217 – 23418HelicalSequence AnalysisAdd
BLAST
Topological domaini235 – 26228NuclearSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. nuclear envelope Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 262262NurimPRO_0000299400Add
BLAST

Proteomic databases

PaxDbiQ6MG14.

Expressioni

Gene expression databases

GenevestigatoriQ6MG14.

Interactioni

Protein-protein interaction databases

BioGridi262960. 1 interaction.
STRINGi10116.ENSRNOP00000001085.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi67 – 726Poly-Leu
Compositional biasi139 – 253115Leu-richAdd
BLAST

Sequence similaritiesi

Belongs to the nurim family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG87490.
GeneTreeiENSGT00390000008146.
HOGENOMiHOG000039993.
HOVERGENiHBG102998.
InParanoidiQ6MG14.
OMAiVYLGLAH.
OrthoDBiEOG7S7SFS.
PhylomeDBiQ6MG14.
TreeFamiTF324853.

Sequencei

Sequence statusi: Complete.

Q6MG14-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAPALLLVPA ALASFVLAFG TGVEFVRFTS LRPLLGGIPE SGGPDARHGW
60 70 80 90 100
LAALQDRSIL ASLAWDLCLL LLFVVQHSLM ATEAVKAWTS RYFGVLQRSL
110 120 130 140 150
YVACTALALQ LVMRYWEATP RGPVLWEARA EPWATWVPLL CFVLHVVSWL
160 170 180 190 200
LIFSILLVFD YAELMGLKQV YYHVLGLGEP LSLKSPRALR LFSHLRHPVC
210 220 230 240 250
VELLTVLWVV PTLGTDRLLL ALLFTLYLGL AHGLDQQDLR YLRSQLQRKL
260
QLLSRPQDGE AE
Length:262
Mass (Da):29,382
Last modified:July 5, 2004 - v1
Checksum:iFEAC40DA59359772
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX883048 Genomic DNA. Translation: CAE84033.1.
RefSeqiNP_997673.1. NM_212508.2.
UniGeneiRn.38521.

Genome annotation databases

EnsembliENSRNOT00000001085; ENSRNOP00000001085; ENSRNOG00000000818.
GeneIDi361791.
KEGGirno:361791.
UCSCiRGD:1302966. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX883048 Genomic DNA. Translation: CAE84033.1 .
RefSeqi NP_997673.1. NM_212508.2.
UniGenei Rn.38521.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 262960. 1 interaction.
STRINGi 10116.ENSRNOP00000001085.

Proteomic databases

PaxDbi Q6MG14.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000001085 ; ENSRNOP00000001085 ; ENSRNOG00000000818 .
GeneIDi 361791.
KEGGi rno:361791.
UCSCi RGD:1302966. rat.

Organism-specific databases

CTDi 11270.
RGDi 1302966. Nrm.

Phylogenomic databases

eggNOGi NOG87490.
GeneTreei ENSGT00390000008146.
HOGENOMi HOG000039993.
HOVERGENi HBG102998.
InParanoidi Q6MG14.
OMAi VYLGLAH.
OrthoDBi EOG7S7SFS.
PhylomeDBi Q6MG14.
TreeFami TF324853.

Miscellaneous databases

NextBioi 677619.
PROi Q6MG14.

Gene expression databases

Genevestigatori Q6MG14.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "The genomic sequence and comparative analysis of the rat major histocompatibility complex."
    Hurt P., Walter L., Sudbrak R., Klages S., Mueller I., Shiina T., Inoko H., Lehrach H., Guenther E., Reinhardt R., Himmelbauer H.
    Genome Res. 14:631-639(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown Norway.

Entry informationi

Entry nameiNRM_RAT
AccessioniPrimary (citable) accession number: Q6MG14
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3