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Protein

Nurim

Gene

Nrm

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Nurim
Alternative name(s):
Nuclear envelope membrane protein
Nuclear rim protein
Gene namesi
Name:Nrm
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 20

Organism-specific databases

RGDi1302966. Nrm.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 4NuclearSequence analysis4
Transmembranei5 – 28HelicalSequence analysisAdd BLAST24
Topological domaini29 – 58Perinuclear spaceSequence analysisAdd BLAST30
Transmembranei59 – 80HelicalSequence analysisAdd BLAST22
Topological domaini81 – 97NuclearSequence analysisAdd BLAST17
Transmembranei98 – 114HelicalSequence analysisAdd BLAST17
Topological domaini115 – 133Perinuclear spaceSequence analysisAdd BLAST19
Transmembranei134 – 164HelicalSequence analysisAdd BLAST31
Topological domaini165 – 191NuclearSequence analysisAdd BLAST27
Transmembranei192 – 210HelicalSequence analysisAdd BLAST19
Topological domaini211 – 216Perinuclear spaceSequence analysis6
Transmembranei217 – 234HelicalSequence analysisAdd BLAST18
Topological domaini235 – 262NuclearSequence analysisAdd BLAST28

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002994001 – 262NurimAdd BLAST262

Proteomic databases

PaxDbiQ6MG14.

Expressioni

Gene expression databases

BgeeiENSRNOG00000000818.
ExpressionAtlasiQ6MG14. baseline and differential.
GenevisibleiQ6MG14. RN.

Interactioni

Protein-protein interaction databases

BioGridi262960. 1 interactor.
STRINGi10116.ENSRNOP00000001085.

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi67 – 72Poly-Leu6
Compositional biasi139 – 253Leu-richAdd BLAST115

Sequence similaritiesi

Belongs to the nurim family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IVGT. Eukaryota.
ENOG4111VYI. LUCA.
GeneTreeiENSGT00390000008146.
HOGENOMiHOG000039993.
HOVERGENiHBG102998.
InParanoidiQ6MG14.
OMAiFIIAFWA.
OrthoDBiEOG091G0MZT.
PhylomeDBiQ6MG14.
TreeFamiTF324853.

Family and domain databases

InterProiIPR033580. Nurim-like.
[Graphical view]
PANTHERiPTHR31040. PTHR31040. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6MG14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPALLLVPA ALASFVLAFG TGVEFVRFTS LRPLLGGIPE SGGPDARHGW
60 70 80 90 100
LAALQDRSIL ASLAWDLCLL LLFVVQHSLM ATEAVKAWTS RYFGVLQRSL
110 120 130 140 150
YVACTALALQ LVMRYWEATP RGPVLWEARA EPWATWVPLL CFVLHVVSWL
160 170 180 190 200
LIFSILLVFD YAELMGLKQV YYHVLGLGEP LSLKSPRALR LFSHLRHPVC
210 220 230 240 250
VELLTVLWVV PTLGTDRLLL ALLFTLYLGL AHGLDQQDLR YLRSQLQRKL
260
QLLSRPQDGE AE
Length:262
Mass (Da):29,382
Last modified:July 5, 2004 - v1
Checksum:iFEAC40DA59359772
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX883048 Genomic DNA. Translation: CAE84033.1.
RefSeqiNP_997673.1. NM_212508.2.
UniGeneiRn.38521.

Genome annotation databases

EnsembliENSRNOT00000001085; ENSRNOP00000001085; ENSRNOG00000000818.
GeneIDi361791.
KEGGirno:361791.
UCSCiRGD:1302966. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX883048 Genomic DNA. Translation: CAE84033.1.
RefSeqiNP_997673.1. NM_212508.2.
UniGeneiRn.38521.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi262960. 1 interactor.
STRINGi10116.ENSRNOP00000001085.

Proteomic databases

PaxDbiQ6MG14.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000001085; ENSRNOP00000001085; ENSRNOG00000000818.
GeneIDi361791.
KEGGirno:361791.
UCSCiRGD:1302966. rat.

Organism-specific databases

CTDi11270.
RGDi1302966. Nrm.

Phylogenomic databases

eggNOGiENOG410IVGT. Eukaryota.
ENOG4111VYI. LUCA.
GeneTreeiENSGT00390000008146.
HOGENOMiHOG000039993.
HOVERGENiHBG102998.
InParanoidiQ6MG14.
OMAiFIIAFWA.
OrthoDBiEOG091G0MZT.
PhylomeDBiQ6MG14.
TreeFamiTF324853.

Miscellaneous databases

PROiQ6MG14.

Gene expression databases

BgeeiENSRNOG00000000818.
ExpressionAtlasiQ6MG14. baseline and differential.
GenevisibleiQ6MG14. RN.

Family and domain databases

InterProiIPR033580. Nurim-like.
[Graphical view]
PANTHERiPTHR31040. PTHR31040. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNRM_RAT
AccessioniPrimary (citable) accession number: Q6MG14
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.