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Protein

Nurim

Gene

Nrm

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Nurim
Alternative name(s):
Nuclear envelope membrane protein
Nuclear rim protein
Gene namesi
Name:Nrm
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494 Componenti: Chromosome 20

Organism-specific databases

RGDi1302966. Nrm.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 44NuclearSequence Analysis
Transmembranei5 – 2824HelicalSequence AnalysisAdd
BLAST
Topological domaini29 – 5830Perinuclear spaceSequence AnalysisAdd
BLAST
Transmembranei59 – 8022HelicalSequence AnalysisAdd
BLAST
Topological domaini81 – 9717NuclearSequence AnalysisAdd
BLAST
Transmembranei98 – 11417HelicalSequence AnalysisAdd
BLAST
Topological domaini115 – 13319Perinuclear spaceSequence AnalysisAdd
BLAST
Transmembranei134 – 16431HelicalSequence AnalysisAdd
BLAST
Topological domaini165 – 19127NuclearSequence AnalysisAdd
BLAST
Transmembranei192 – 21019HelicalSequence AnalysisAdd
BLAST
Topological domaini211 – 2166Perinuclear spaceSequence Analysis
Transmembranei217 – 23418HelicalSequence AnalysisAdd
BLAST
Topological domaini235 – 26228NuclearSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. nuclear envelope Source: UniProtKB
  3. nuclear inner membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 262262NurimPRO_0000299400Add
BLAST

Proteomic databases

PaxDbiQ6MG14.

Expressioni

Gene expression databases

GenevestigatoriQ6MG14.

Interactioni

Protein-protein interaction databases

BioGridi262960. 1 interaction.
STRINGi10116.ENSRNOP00000001085.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi67 – 726Poly-Leu
Compositional biasi139 – 253115Leu-richAdd
BLAST

Sequence similaritiesi

Belongs to the nurim family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG87490.
GeneTreeiENSGT00390000008146.
HOGENOMiHOG000039993.
HOVERGENiHBG102998.
InParanoidiQ6MG14.
OMAiHSLDKQD.
OrthoDBiEOG7S7SFS.
PhylomeDBiQ6MG14.
TreeFamiTF324853.

Sequencei

Sequence statusi: Complete.

Q6MG14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPALLLVPA ALASFVLAFG TGVEFVRFTS LRPLLGGIPE SGGPDARHGW
60 70 80 90 100
LAALQDRSIL ASLAWDLCLL LLFVVQHSLM ATEAVKAWTS RYFGVLQRSL
110 120 130 140 150
YVACTALALQ LVMRYWEATP RGPVLWEARA EPWATWVPLL CFVLHVVSWL
160 170 180 190 200
LIFSILLVFD YAELMGLKQV YYHVLGLGEP LSLKSPRALR LFSHLRHPVC
210 220 230 240 250
VELLTVLWVV PTLGTDRLLL ALLFTLYLGL AHGLDQQDLR YLRSQLQRKL
260
QLLSRPQDGE AE
Length:262
Mass (Da):29,382
Last modified:July 4, 2004 - v1
Checksum:iFEAC40DA59359772
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX883048 Genomic DNA. Translation: CAE84033.1.
RefSeqiNP_997673.1. NM_212508.2.
UniGeneiRn.38521.

Genome annotation databases

EnsembliENSRNOT00000001085; ENSRNOP00000001085; ENSRNOG00000000818.
GeneIDi361791.
KEGGirno:361791.
UCSCiRGD:1302966. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX883048 Genomic DNA. Translation: CAE84033.1.
RefSeqiNP_997673.1. NM_212508.2.
UniGeneiRn.38521.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi262960. 1 interaction.
STRINGi10116.ENSRNOP00000001085.

Proteomic databases

PaxDbiQ6MG14.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000001085; ENSRNOP00000001085; ENSRNOG00000000818.
GeneIDi361791.
KEGGirno:361791.
UCSCiRGD:1302966. rat.

Organism-specific databases

CTDi11270.
RGDi1302966. Nrm.

Phylogenomic databases

eggNOGiNOG87490.
GeneTreeiENSGT00390000008146.
HOGENOMiHOG000039993.
HOVERGENiHBG102998.
InParanoidiQ6MG14.
OMAiHSLDKQD.
OrthoDBiEOG7S7SFS.
PhylomeDBiQ6MG14.
TreeFamiTF324853.

Miscellaneous databases

NextBioi677619.
PROiQ6MG14.

Gene expression databases

GenevestigatoriQ6MG14.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "The genomic sequence and comparative analysis of the rat major histocompatibility complex."
    Hurt P., Walter L., Sudbrak R., Klages S., Mueller I., Shiina T., Inoko H., Lehrach H., Guenther E., Reinhardt R., Himmelbauer H.
    Genome Res. 14:631-639(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown Norway.

Entry informationi

Entry nameiNRM_RAT
AccessioniPrimary (citable) accession number: Q6MG14
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 10, 2007
Last sequence update: July 4, 2004
Last modified: January 6, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.