Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA-directed RNA polymerase subunit beta

Gene

rpoB

Organism
Protochlamydia amoebophila (strain UWE25)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Enzyme and pathway databases

BioCyciPAMO264201:GH0M-619-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit betaUniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP subunit betaUniRule annotation
Alternative name(s):
RNA polymerase subunit betaUniRule annotation
Transcriptase subunit betaUniRule annotation
Gene namesi
Name:rpoBUniRule annotation
Ordered Locus Names:pc0604
OrganismiProtochlamydia amoebophila (strain UWE25)
Taxonomic identifieri264201 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesParachlamydiaceaeCandidatus Protochlamydia
Proteomesi
  • UP000000529 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12541254DNA-directed RNA polymerase subunit betaPRO_0000224087Add
BLAST

Proteomic databases

PRIDEiQ6MDM1.

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Protein-protein interaction databases

STRINGi264201.pc0604.

Structurei

3D structure databases

ProteinModelPortaliQ6MDM1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QIH. Bacteria.
COG0085. LUCA.
HOGENOMiHOG000218611.
KOiK03043.
OMAiYFNPKRY.
OrthoDBiEOG6M9DS6.

Family and domain databases

Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 2 hits.
3.90.1110.10. 2 hits.
HAMAPiMF_01321. RNApol_bact_RpoB.
InterProiIPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR010243. RNA_pol_bsu_bac.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 3 hits.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6MDM1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLQRPPHRES FNDKEEIIDL PNLIEIQIKS YNQFLQADKF PDERENIGLQ
60 70 80 90 100
EVFTEIFPIK SYDEKTILEF LSYNLGVPKY NPEECIRRGI TYNVTLKVKF
110 120 130 140 150
RLTDETGIKE EEVYMGTIPV MTDKGTFIVN GAERVVVSQL HRSPGICFEQ
160 170 180 190 200
ERHSRGNVIY SFRIIPYRGS WLEGAFDTND LIHIYIDRKK RRRKILATTF
210 220 230 240 250
IRALGYSSNS DIIEEFFTTR KYKIKNEKEF AKLVGKILAQ DVVDEESGLV
260 270 280 290 300
FGKASEKLTT AMLKRIVDAG IDVIRIAEDA DETSPVIKML AKDPTDSYES
310 320 330 340 350
ALKDFYRKIR PGEPATLSNA RSAIMRLFFD PKRYNLGRVG RYKLNSKLGC
360 370 380 390 400
EINDEKLQTV TLDKEDVIGA LKYLIMLKSG SEEASIDDID HLGNRRVRSV
410 420 430 440 450
GELIQNQCRI GLARMEKIIR ERMNLFDFSS DTLTPGKIVS AKGLSGVLKD
460 470 480 490 500
FFGRSQLSQF MDQTNPIAEL THKRRLSSLG PGGLNRDRAG FEVRDVHTSH
510 520 530 540 550
YGRICPIETP EGPNIGLISS LSSFAKINEF GFIETPYRIV REGVVTDEIE
560 570 580 590 600
YMTADQEEQC VIAQASAPLD EYHMFAEPIC WARYKGEQFE TDTKNVTHMD
610 620 630 640 650
VSPKQLVSIV TGLIPFLEHD DANRALMGSN MQRQGVPLLK PTAPIVGTGL
660 670 680 690 700
EARAARDSGA VLIAHEDGVV DYVDGLKIVI SPDDNRLEKR TYLLKKFIRS
710 720 730 740 750
NAGTCINQRP LCHVGDKIKA GDVIADGPAT DKGEVALGRN VLVAFMPWFG
760 770 780 790 800
YNYEDAIIIS EKLLREDYYT SLYIEEFELT ARDTKLGKEE ITRDIPNVSE
810 820 830 840 850
ETLRNLNDDG IIRIGAEVKP GDTLVGKITP KSETELAPEE RLLRAIFGDK
860 870 880 890 900
ASDVKDASLI APPGTEGVVM DVKVFSRRDR LSKTDDELVE EASKLKDIQR
910 920 930 940 950
EYKSNQAQLR TEKHERVGAL LLNETAPGNI VHRRTAEIIV DEGDLITQDL
960 970 980 990 1000
IEALEKESVE DLLMPENDIY TTLRQILHDY EIALQTVETQ YKTQLEFMRK
1010 1020 1030 1040 1050
GDTDLDPGVI RQVKVYVASK RKLQVGDKMA GRHGNKGVVS KIVPEADMPF
1060 1070 1080 1090 1100
LSTGQTIEII LNPLGVPSRM NMGQLFETHL GIAAKHTGIT VKSPVFEGFP
1110 1120 1130 1140 1150
EEKIWEMMKK AGLPEDGKFF LYDGCSGERF DNSVVVGYIY MLKLSHLVAD
1160 1170 1180 1190 1200
KIHARAVGPY SLVTQQPLGG KAQMGGQRFG EMEVWAAEAY GAAHLLQEML
1210 1220 1230 1240 1250
TVKSDDVAGR TRIYESIVKG ENLLKSGTPE SFNVLIKEMQ GLGLNVYTEA

VDDS
Length:1,254
Mass (Da):140,972
Last modified:July 5, 2004 - v1
Checksum:i8D3331B7243755E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX908798 Genomic DNA. Translation: CAF23328.1.

Genome annotation databases

EnsemblBacteriaiCAF23328; CAF23328; pc0604.
KEGGipcu:pc0604.
PATRICi31996514. VBICanPro72727_0606.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX908798 Genomic DNA. Translation: CAF23328.1.

3D structure databases

ProteinModelPortaliQ6MDM1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi264201.pc0604.

Proteomic databases

PRIDEiQ6MDM1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAF23328; CAF23328; pc0604.
KEGGipcu:pc0604.
PATRICi31996514. VBICanPro72727_0606.

Phylogenomic databases

eggNOGiENOG4107QIH. Bacteria.
COG0085. LUCA.
HOGENOMiHOG000218611.
KOiK03043.
OMAiYFNPKRY.
OrthoDBiEOG6M9DS6.

Enzyme and pathway databases

BioCyciPAMO264201:GH0M-619-MONOMER.

Family and domain databases

Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 2 hits.
3.90.1110.10. 2 hits.
HAMAPiMF_01321. RNApol_bact_RpoB.
InterProiIPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR010243. RNA_pol_bsu_bac.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 3 hits.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UWE25.

Entry informationi

Entry nameiRPOB_PARUW
AccessioniPrimary (citable) accession number: Q6MDM1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: July 5, 2004
Last modified: July 6, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.