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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Protochlamydia amoebophila (strain UWE25)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei77NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:pc0759
OrganismiProtochlamydia amoebophila (strain UWE25)
Taxonomic identifieri264201 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeParachlamydialesParachlamydiaceaeCandidatus Protochlamydia
Proteomesi
  • UP000000529 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001218801 – 262tRNA pseudouridine synthase BAdd BLAST262

Interactioni

Protein-protein interaction databases

STRINGi264201.pc0759

Structurei

3D structure databases

ProteinModelPortaliQ6MD66
SMRiQ6MD66
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T Bacteria
COG0130 LUCA
HOGENOMiHOG000231223
KOiK03177
OMAiVDCSKGT
OrthoDBiPOG091H02G9

Family and domain databases

HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR014780 tRNA_psdUridine_synth_TruB
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

Q6MD66-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MINTCALKNY LEKSQKKESP AKETIVTSLN RSLSTPPSHL EGILLINKPK
60 70 80 90 100
GKTSFSLVRD LRKRLGVKKI GHAGTLDPFA TGVMVMLVGR NYTRLSDQFL
110 120 130 140 150
LSDKEYIAEA YLGVVTDSYD CEGQVLSQSN IIPTLEQIKE AFSLFQGKIE
160 170 180 190 200
QVPPMFSAKK QQGKKLYELA RQGIVVERQP VKISIHTELL SYNYPYLNFR
210 220 230 240 250
IECSKGTYIR SIAYDLGTKL GCGAHLSNLT RTRSGAFCLE NCLNGAEIHT
260
VTNLEQNLIR ND
Length:262
Mass (Da):29,308
Last modified:July 5, 2004 - v1
Checksum:i53BA973B2195CFD5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX908798 Genomic DNA Translation: CAF23483.1

Genome annotation databases

EnsemblBacteriaiCAF23483; CAF23483; pc0759
KEGGipcu:pc0759

Similar proteinsi

Entry informationi

Entry nameiTRUB_PARUW
AccessioniPrimary (citable) accession number: Q6MD66
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: July 5, 2004
Last modified: March 28, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health