Q6MD07 (GCP_PARUW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	pc0818

Organism

Protochlamydia amoebophila (strain UWE25) [Complete proteome] [HAMAP]

Taxonomic identifier

264201 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Parachlamydiaceae › Candidatus Protochlamydia

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 343	343	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303488

Sequences

	Sequence		Length	Mass (Da)
	Q6MD07 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 25BC0E659C589AE1	FASTA	343	37,038
	10 20 30 40 50 60 MLVLGIESTC DETACAIVRD GKDILSNIVA SQIDLHKEYG GVVPELACRR HIDLIIPVID 70 80 90 100 110 120 QALNQAKLTL EQIDLIAVAN GPGLIGALLI GLNTAKALAL ALRKPFIGIN HVEAHLYAAI 130 140 150 160 170 180 MSHPQDFQFP CLGVVLSGGH TALVLIKQIG QYELIGQTVD DAVGEAFDKV AKMLNLPYPG 190 200 210 220 230 240 GPEIENLARH GRSVKFNFKA GQVKGRPLDF SFSGLKTAVL YAIKDPKALK EMVLLSSEMT 250 260 270 280 290 300 QDIAASFQEA ACSDIVKKSL LAAKQYGVNT LLFGGGVTNN CYLRKLFSVA NSNLNYIWPS 310 320 330 340 AGLSLDNAAM IAGLGYYRYQ LQNKSDSMDL EPLTRTPLQS VKE

References

[1]

"Illuminating the evolutionary history of chlamydiae." Horn M., Collingro A., Schmitz-Esser S., Beier C.L., Purkhold U., Fartmann B., Brandt P., Nyakatura G.J., Droege M., Frishman D., Rattei T., Mewes H.-W., Wagner M. Science 304:728-730(2004) [PubMed: 15073324] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: UWE25.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX908798 Genomic DNA. Translation: CAF23542.1.
RefSeq	YP_007817.1. NC_005861.1.
3D structure databases
ProteinModelPortal	Q6MD07.
ModBase	Search...
Protein-protein interaction databases
STRING	Q6MD07.
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2781206.
GenomeReviews	Gene locus pc0818 in contig BX908798_GR.
KEGG	pcu:pc0818.
NMPDR	fig|264201.1.peg.818.
PATRIC	31996970. VBICanPro72727_0829.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0533.
HOGENOM	HBG304663.
OMA	MEVIGQT.
PhylomeDB	Q6MD07.
ProtClustDB	CLSK2762266.
Enzyme and pathway databases
BioCyc	CPRO264201:PC0818-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_PARUW

Accession

Primary (citable) accession number: Q6MD07

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program