SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6MBP0

- TRMB_PARUW

UniProt

Q6MBP0 - TRMB_PARUW

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene
trmB, pc1285
Organism
Protochlamydia amoebophila (strain UWE25)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei56 – 561S-adenosyl-L-methionine By similarity
Binding sitei81 – 811S-adenosyl-L-methionine By similarity
Binding sitei108 – 1081S-adenosyl-L-methionine By similarity
Active sitei131 – 1311 By similarity
Binding sitei131 – 1311S-adenosyl-L-methionine By similarity
Binding sitei135 – 1351Substrate By similarity
Binding sitei167 – 1671Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPAMO264201:GH0M-1315-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene namesi
Name:trmB
Ordered Locus Names:pc1285
OrganismiProtochlamydia amoebophila (strain UWE25)
Taxonomic identifieri264201 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesParachlamydiaceaeCandidatus Protochlamydia
ProteomesiUP000000529: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 225225tRNA (guanine-N(7)-)-methyltransferaseUniRule annotationPRO_0000171367Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi264201.pc1285.

Structurei

3D structure databases

ProteinModelPortaliQ6MBP0.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000034940.
KOiK03439.
OMAiIVELAMN.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6MBP0-1 [UniParc]FASTAAdd to Basket

« Hide

MKPKDLKSPF KWEHRQIVIQ DRVWYVPDQH LSDIPFIFPG WTHDQTFAQD    50
KPIYLEYCSG NGAWIASKAI EQSQYNWVGI EKKFDRTRKI WSKIKKFELD 100
NLLTICGEGF HVTRDFFANE SVDAVFINFP DPWPKKRHAK HRIVQPAFVK 150
EIHRILKSDK LFTLVTDDAA YSKIMIDVIY QTGGFISLFE APYYTTSYPG 200
YGSSYFEELW REKGKSIHYH VFRKI 225
Length:225
Mass (Da):26,668
Last modified:July 5, 2004 - v1
Checksum:iFD16CA5200615259
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX908798 Genomic DNA. Translation: CAF24009.1.
RefSeqiYP_008284.1. NC_005861.1.

Genome annotation databases

EnsemblBacteriaiCAF24009; CAF24009; pc1285.
GeneIDi2780395.
KEGGipcu:pc1285.
PATRICi31997960. VBICanPro72727_1314.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX908798 Genomic DNA. Translation: CAF24009.1 .
RefSeqi YP_008284.1. NC_005861.1.

3D structure databases

ProteinModelPortali Q6MBP0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 264201.pc1285.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAF24009 ; CAF24009 ; pc1285 .
GeneIDi 2780395.
KEGGi pcu:pc1285.
PATRICi 31997960. VBICanPro72727_1314.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000034940.
KOi K03439.
OMAi IVELAMN.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci PAMO264201:GH0M-1315-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UWE25.

Entry informationi

Entry nameiTRMB_PARUW
AccessioniPrimary (citable) accession number: Q6MBP0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: July 5, 2004
Last modified: June 11, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi