ID   Q6MBC4_PARUW            Unreviewed;       529 AA.
AC   Q6MBC4;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 115.
DE   RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN   ORFNames=PC_RS10005 {ECO:0000313|EMBL:CAF24125.1};
OS   Protochlamydia amoebophila (strain UWE25).
OC   Bacteria; Chlamydiota; Chlamydiia; Parachlamydiales; Parachlamydiaceae;
OC   Protochlamydia.
OX   NCBI_TaxID=264201 {ECO:0000313|EMBL:CAF24125.1, ECO:0000313|Proteomes:UP000000529};
RN   [1] {ECO:0000313|EMBL:CAF24125.1, ECO:0000313|Proteomes:UP000000529}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UWE25 {ECO:0000313|EMBL:CAF24125.1,
RC   ECO:0000313|Proteomes:UP000000529};
RX   PubMed=15073324; DOI=10.1126/science.1096330;
RA   Horn M., Collingro A., Schmitz-Esser S., Beier C.L., Purkhold U.,
RA   Fartmann B., Brandt P., Nyakatura G.J., Droege M., Frishman D., Rattei T.,
RA   Mewes H., Wagner M.;
RT   "Illuminating the evolutionary history of chlamydiae.";
RL   Science 304:728-730(2004).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC         [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001433};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC         threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC         Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC         EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR   EMBL; BX908798; CAF24125.1; -; Genomic_DNA.
DR   RefSeq; WP_011175950.1; NC_005861.2.
DR   AlphaFoldDB; Q6MBC4; -.
DR   STRING; 264201.pc1401; -.
DR   KEGG; pcu:PC_RS10005; -.
DR   eggNOG; COG0515; Bacteria.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_042256_0_0_0; -.
DR   OrthoDB; 9788659at2; -.
DR   Proteomes; UP000000529; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0010506; P:regulation of autophagy; IEA:InterPro.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR045269; Atg1-like.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   PANTHER; PTHR24348:SF74; KINASE, PUTATIVE-RELATED; 1.
DR   PANTHER; PTHR24348; SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000529}.
FT   DOMAIN          31..334
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
SQ   SEQUENCE   529 AA;  59365 MW;  50410C46ABAC2FA8 CRC64;
     MELDPSKRIT LPTALDSTKN IVKIPEKIGP YQVEALLEKG GMSILYLATH PDTKDPITIK
     VLFPEFVSNP EMVQRFLRES EIIGLADHPN IVKLYGQGEW EGGLYIAMEF IQGISLRQYL
     LRNLISLKHA LELVMEISMA LCHLHAHGVI HRDVKPENIL VTESGGVKVI DFGIAQLLTE
     GQTDPKSQRR LIGTPIYMSP EQKNNPESTS YPSDIYSLGI ITYELVLGKL SHGQIHLSIM
     PKGLQKILAK ALQLNPEDRY QDIVDFMTDV SAYLYSPALL KENKELDPLS DLSESLRHAQ
     HSLVPDNPPK WSKIDIGLAS YKSLGISSLY YDFFNLPHHG YGIIIGEPSV KGSAGIVYTS
     VLRGMVRALC QLTQRPEEMA TVLNALLLND PMKQNFSFSY LILSPQENLF RFISCGCGHL
     WYLPKEKLQL ELINSENSPL GINHLNSFVE IEHPWNVGDA ILFYGSLCSS DTFAKKPLFS
     NEQLLSSLQE ASMTSPQKQV DTILRKAKVE LSRTSDERSI VLLNLLRNE
//