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Q6MB39 (Q6MB39_PARUW) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183
Gene names
Name:ald EMBL CAF24210.1
Ordered Locus Names:pc1486
OrganismProtochlamydia amoebophila (strain UWE25) [Complete proteome] [HAMAP]
Taxonomic identifier264201 [NCBI]
Taxonomic lineageBacteria › Chlamydiae › Chlamydiales › Parachlamydiaceae › Candidatus Protochlamydia

Protein attributes

Sequence length370 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183

Pathway

Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183

Sequence similarities

Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
   LigandNAD PIRNR PIRNR000183
   Molecular functionOxidoreductase PIRNR PIRNR000183
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionalanine dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q6MB39 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 41E8B7DD0E56169E

FASTA37039,720
        10         20         30         40         50         60 
MIIGIPKEIK NHEYRVGATP SMVRLLVDAG HQVFVQSLAG DKIGYNDEMF TRAGAKIVQS 

        70         80         90        100        110        120 
AEEVYNSEMI IKVKEPQLSE FPLLKEGQIL FCYLHLAPDP EQTKHLVEKK VVAIAYETVT 

       130        140        150        160        170        180 
DVQGRLPLLI PMSEIAGRIA IQVGATSLQL NYGGQGLLLG GVPGVAPAEV VVIGGGVVGT 

       190        200        210        220        230        240 
EAARMALGLG ASVTIFDRDL NRLRFLDALY GPTLKTMYSS PLTIEEAVSK AALVIGAVLI 

       250        260        270        280        290        300 
PGKTAPKLVT RKMIQKMSPG TVVVDVAIDQ GGCMETSRPT THTEPTYVVD GVLHYCVTNM 

       310        320        330        340        350        360 
PGTCARTSTQ ALTNATTEYA LVIANKGWKK ALLDHVGLRH GLNVCFGQIT NESVAYDLGY 

       370 
TYVPAENLLS

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References

[1]"Illuminating the evolutionary history of chlamydiae."
Horn M., Collingro A., Schmitz-Esser S., Beier C.L., Purkhold U., Fartmann B., Brandt P., Nyakatura G.J., Droege M., Frishman D., Rattei T., Mewes H.-W., Wagner M.
Science 304:728-730(2004) [PubMed: 15073324] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX908798 Genomic DNA. Translation: CAF24210.1.
RefSeqYP_008485.1. NC_005861.1.

3D structure databases

ProteinModelPortalQ6MB39.
SMRQ6MB39. Positions 1-356.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6MB39.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2781143.
GenomeReviewsGene locus pc1486 in contig BX908798_GR.
KEGGpcu:pc1486.
NMPDRfig|264201.1.peg.1486.
PATRIC31998378. VBICanPro72727_1521.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0686.
HOGENOMHBG289735.
OMAVAHGHEV.
ProtClustDBCLSK2762408.

Family and domain databases

InterProIPR008143. Ala_DH/PNT_CS2.
IPR008141. Ala_DH/Pyr_transHydgase.
IPR007886. AlaDH/PNT_N.
IPR007698. AlaDH/PNT_NAD(H)-bd.
[Graphical view]
KOK00259.
PANTHERPTHR10160:SF3. PTHR10160:SF3. 1 hit.
PfamPF01262. AlaDh_PNT_C. 1 hit.
PF05222. AlaDh_PNT_N. 1 hit.
[Graphical view]
PIRSFPIRSF000183. Alanine_dh. 1 hit.
SMARTSM01002. AlaDh_PNT_C. 1 hit.
SM01003. AlaDh_PNT_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00518. AlaDH. 1 hit.
PROSITEPS00837. ALADH_PNT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6MB39_PARUW
AccessionPrimary (citable) accession number: Q6MB39
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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