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Q6MAN0 (PKND_PARUW) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase PknD

EC=2.7.11.1
Gene names
Name:pknD
Ordered Locus Names:pc1645
OrganismProtochlamydia amoebophila (strain UWE25) [Complete proteome] [HAMAP]
Taxonomic identifier264201 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesParachlamydiaceaeCandidatus Protochlamydia

Protein attributes

Sequence length982 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth By similarity. HAMAP-Rule MF_01957

Catalytic activity

ATP + a protein = ADP + a phosphoprotein. HAMAP-Rule MF_01957

Post-translational modification

Autophosphorylated on serine and threonine residues By similarity. HAMAP-Rule MF_01957

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 982982Serine/threonine-protein kinase PknD HAMAP-Rule MF_01957
PRO_0000239302

Regions

Domain51 – 342292Protein kinase
Nucleotide binding57 – 659ATP By similarity

Sites

Active site1861Proton acceptor By similarity
Binding site801ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6MAN0 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: F3AAA39404B80D89

FASTA982113,378
        10         20         30         40         50         60 
MPHSFPDYSF TCPFCKNNCK LSFAQCPAFC PFCGKSQKNE STGLPIQSDF YQIIKSIGKG 

        70         80         90        100        110        120 
GMGEVFLAYD PCYERQIAIK KIRSDLLEHP QIKKRFLKEA HMTSQLTHPA IIPIYTIRSD 

       130        140        150        160        170        180 
ADTAYYTMPF VEGDTLKQII RKTKLQEKNG ETLDYLGGSI LALMRVFITI CQAVAYAHSK 

       190        200        210        220        230        240 
GVLHRDLKPE NIIIGKYGEV LILDWGLAKF IDQSPEEELL ASFPESLTKQ KDITKIGKVV 

       250        260        270        280        290        300 
GTVAYMAPER ALGQPATIQT DIYSLGVILY QLLTLKSPFK RGTLDEFRKN MSREEWQDPV 

       310        320        330        340        350        360 
TAAPYREVPR MLASFTEKCL SLDLQNRYQS VEELIRDIEN YLEGRSEWFC IANLNTKEKN 

       370        380        390        400        410        420 
DWEFQENVLI AEHVAITRMT DDAEWVSLMI SKQSFTGNTK IEADVCLGEQ GHGIGFLLSV 

       430        440        450        460        470        480 
PEASAREHLI EGYCLWLGSD FSKTTKLLRS NVEVVHAPDI FLKRQQTYHV RIEKVDKSIH 

       490        500        510        520        530        540 
VYINDNLQFS YIAHIPLIGT HVGLLSRDAD FEISPLEIYV GNLNINVNCL AVPDAFLAHR 

       550        560        570        580        590        600 
DYNQALSEYR RIAYSFPDRT EGREALFRAG LTFLEQAKTA ENKMPLLEEA LNEFEKLHGT 

       610        620        630        640        650        660 
PSAPLEYLGK ALAYESINDS EEEIKCYELA YRRYPNHPIL PMLQEQIISR LHEVSRMQRI 

       670        680        690        700        710        720 
TTYRFTLLTV RHLPLNKIDT HTKRLFNSLQ KHWEVLPFIE YKSPSPLTTL STRFATPLAF 

       730        740        750        760        770        780 
WLAKPFILGE ILDDLIQSPP FPIEEVNNAL LCLVELGSWE YAQEKLNTIQ TYLNLPQNPK 

       790        800        810        820        830        840 
WLDLKAFIAC HYQTLEDVYK DFFFQIPSTN ADHLHAVLYF MDQCLDQLNT SLIYTLARQF 

       850        860        870        880        890        900 
EHAELSFEDR LRLNCRRVWA YLLDKNWQDA GNLLYTYSVE TLNKDSSLLH FLYGCWLQVT 

       910        920        930        940        950        960 
EGAEIANVHF AGVNPVMFPR TWTLGARFLT NNLSKDSYEK AFMWEKRQLC KQLILYYHCV 

       970        980 
GNETKRIHFQ KLYQEQFIHA EL 

« Hide

References

[1]"Illuminating the evolutionary history of chlamydiae."
Horn M., Collingro A., Schmitz-Esser S., Beier C.L., Purkhold U., Fartmann B., Brandt P., Nyakatura G.J., Droege M., Frishman D., Rattei T., Mewes H.-W., Wagner M.
Science 304:728-730(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: UWE25.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX908798 Genomic DNA. Translation: CAF24369.1.
RefSeqYP_008644.1. NC_005861.1.

3D structure databases

ProteinModelPortalQ6MAN0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING264201.pc1645.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAF24369; CAF24369; pc1645.
GeneID2780931.
KEGGpcu:pc1645.
PATRIC31998702. VBICanPro72727_1680.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000115565.
KOK08884.
OrthoDBEOG6W45P7.

Enzyme and pathway databases

BioCycPAMO264201:GH0M-1681-MONOMER.

Family and domain databases

Gene3D1.25.40.10. 2 hits.
HAMAPMF_01957. PknD_kinase.
InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR023507. Ser/Thr_kinase_PknD.
IPR011990. TPR-like_helical.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKND_PARUW
AccessionPrimary (citable) accession number: Q6MAN0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: July 5, 2004
Last modified: February 19, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families