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Q6MAN0

- PKND_PARUW

UniProt

Q6MAN0 - PKND_PARUW

Protein

Serine/threonine-protein kinase PknD

Gene

pknD

Organism
Protochlamydia amoebophila (strain UWE25)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth.UniRule annotation

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei80 – 801ATPUniRule annotation
    Active sitei186 – 1861Proton acceptorUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi57 – 659ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. protein serine/threonine kinase activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciPAMO264201:GH0M-1681-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein kinase PknDUniRule annotation (EC:2.7.11.1UniRule annotation)
    Gene namesi
    Name:pknDUniRule annotation
    Ordered Locus Names:pc1645
    OrganismiProtochlamydia amoebophila (strain UWE25)
    Taxonomic identifieri264201 [NCBI]
    Taxonomic lineageiBacteriaChlamydiaeChlamydialesParachlamydiaceaeCandidatus Protochlamydia
    ProteomesiUP000000529: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 982982Serine/threonine-protein kinase PknDPRO_0000239302Add
    BLAST

    Post-translational modificationi

    Autophosphorylated on serine and threonine residues.UniRule annotation

    Keywords - PTMi

    Phosphoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi264201.pc1645.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6MAN0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini51 – 342292Protein kinaseUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.UniRule annotation
    Contains 1 protein kinase domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000115565.
    KOiK08884.
    OrthoDBiEOG6W45P7.

    Family and domain databases

    Gene3Di1.25.40.10. 2 hits.
    HAMAPiMF_01957. PknD_kinase.
    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    IPR023507. Ser/Thr_kinase_PknD.
    IPR011990. TPR-like_helical.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q6MAN0-1 [UniParc]FASTAAdd to Basket

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    MPHSFPDYSF TCPFCKNNCK LSFAQCPAFC PFCGKSQKNE STGLPIQSDF    50
    YQIIKSIGKG GMGEVFLAYD PCYERQIAIK KIRSDLLEHP QIKKRFLKEA 100
    HMTSQLTHPA IIPIYTIRSD ADTAYYTMPF VEGDTLKQII RKTKLQEKNG 150
    ETLDYLGGSI LALMRVFITI CQAVAYAHSK GVLHRDLKPE NIIIGKYGEV 200
    LILDWGLAKF IDQSPEEELL ASFPESLTKQ KDITKIGKVV GTVAYMAPER 250
    ALGQPATIQT DIYSLGVILY QLLTLKSPFK RGTLDEFRKN MSREEWQDPV 300
    TAAPYREVPR MLASFTEKCL SLDLQNRYQS VEELIRDIEN YLEGRSEWFC 350
    IANLNTKEKN DWEFQENVLI AEHVAITRMT DDAEWVSLMI SKQSFTGNTK 400
    IEADVCLGEQ GHGIGFLLSV PEASAREHLI EGYCLWLGSD FSKTTKLLRS 450
    NVEVVHAPDI FLKRQQTYHV RIEKVDKSIH VYINDNLQFS YIAHIPLIGT 500
    HVGLLSRDAD FEISPLEIYV GNLNINVNCL AVPDAFLAHR DYNQALSEYR 550
    RIAYSFPDRT EGREALFRAG LTFLEQAKTA ENKMPLLEEA LNEFEKLHGT 600
    PSAPLEYLGK ALAYESINDS EEEIKCYELA YRRYPNHPIL PMLQEQIISR 650
    LHEVSRMQRI TTYRFTLLTV RHLPLNKIDT HTKRLFNSLQ KHWEVLPFIE 700
    YKSPSPLTTL STRFATPLAF WLAKPFILGE ILDDLIQSPP FPIEEVNNAL 750
    LCLVELGSWE YAQEKLNTIQ TYLNLPQNPK WLDLKAFIAC HYQTLEDVYK 800
    DFFFQIPSTN ADHLHAVLYF MDQCLDQLNT SLIYTLARQF EHAELSFEDR 850
    LRLNCRRVWA YLLDKNWQDA GNLLYTYSVE TLNKDSSLLH FLYGCWLQVT 900
    EGAEIANVHF AGVNPVMFPR TWTLGARFLT NNLSKDSYEK AFMWEKRQLC 950
    KQLILYYHCV GNETKRIHFQ KLYQEQFIHA EL 982
    Length:982
    Mass (Da):113,378
    Last modified:July 5, 2004 - v1
    Checksum:iF3AAA39404B80D89
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX908798 Genomic DNA. Translation: CAF24369.1.
    RefSeqiYP_008644.1. NC_005861.1.

    Genome annotation databases

    EnsemblBacteriaiCAF24369; CAF24369; pc1645.
    GeneIDi2780931.
    KEGGipcu:pc1645.
    PATRICi31998702. VBICanPro72727_1680.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX908798 Genomic DNA. Translation: CAF24369.1 .
    RefSeqi YP_008644.1. NC_005861.1.

    3D structure databases

    ProteinModelPortali Q6MAN0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 264201.pc1645.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAF24369 ; CAF24369 ; pc1645 .
    GeneIDi 2780931.
    KEGGi pcu:pc1645.
    PATRICi 31998702. VBICanPro72727_1680.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000115565.
    KOi K08884.
    OrthoDBi EOG6W45P7.

    Enzyme and pathway databases

    BioCyci PAMO264201:GH0M-1681-MONOMER.

    Family and domain databases

    Gene3Di 1.25.40.10. 2 hits.
    HAMAPi MF_01957. PknD_kinase.
    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    IPR023507. Ser/Thr_kinase_PknD.
    IPR011990. TPR-like_helical.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: UWE25.

    Entry informationi

    Entry nameiPKND_PARUW
    AccessioniPrimary (citable) accession number: Q6MAN0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 13, 2006
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3