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Q6M1A3 (TRUD1_METMP) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable tRNA pseudouridine synthase D 1

EC=5.4.99.27
Alternative name(s):
tRNA pseudouridine(13) synthase
tRNA pseudouridylate synthase D 1
tRNA-uridine isomerase D 1
Gene names
Name:truD1
Ordered Locus Names:MMP0014
OrganismMethanococcus maripaludis (strain S2 / LL) [Complete proteome] [HAMAP]
Taxonomic identifier267377 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus

Protein attributes

Sequence length389 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs By similarity.

Catalytic activity

tRNA uridine13 = tRNA pseudouridine13.

Sequence similarities

Belongs to the pseudouridine synthase TruD family.

Contains 1 TRUD domain.

Ontologies

Keywords
   Biological processtRNA processing
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpseudouridine synthesis

Inferred from electronic annotation. Source: InterPro

tRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: InterPro

pseudouridine synthase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 389389Probable tRNA pseudouridine synthase D 1
PRO_0000152544

Regions

Domain135 – 345211TRUD

Sites

Active site631Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6M1A3 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 15F89137BFB03189

FASTA38946,201
        10         20         30         40         50         60 
MKFRQKHEDF IVNEILEYEL NDYGNYFLYK LQKNGIENLK AISYLSKNFE VPTKEIGYCG 

        70         80         90        100        110        120 
LKDRHAITTQ YVSIPKEYGK LSLDEDNLKL EYVGTIEKPL KIGRLYGNRF EIIARAVDKD 

       130        140        150        160        170        180 
EFLKIADNIR NLSSGAPNYY DDQRFGSVFN GKFIAKEILK GNYEEVVKIL LTSYTKSEKK 

       190        200        210        220        230        240 
QLKDLKRFIA KNWGNWDECL EYIDKKQIRS KMFRNMVKSL TYENDFKKAF KYVDNRLKEL 

       250        260        270        280        290        300 
FISAYQSYLW NECLKEFLKE VIPKENRIYV DYSCGTFLFY ENIEEELFDK LKEMDFPTIV 

       310        320        330        340        350        360 
SDVEYTDPEK RIIKAILKKE RIKISDFEKL DFGKLKYTKR PIISIPEDVN TGKFKSDELN 

       370        380 
SKKYKIDLEF SLKKGSYATI ILKRVFNIL 

« Hide

References

[1]"Complete genome sequence of the genetically tractable hydrogenotrophic methanogen Methanococcus maripaludis."
Hendrickson E.L., Kaul R., Zhou Y., Bovee D., Chapman P., Chung J., Conway de Macario E., Dodsworth J.A., Gillett W., Graham D.E., Hackett M., Haydock A.K., Kang A., Land M.L., Levy R., Lie T.J., Major T.A., Moore B.C. expand/collapse author list , Porat I., Palmeiri A., Rouse G., Saenphimmachak C., Soell D., Van Dien S., Wang T., Whitman W.B., Xia Q., Zhang Y., Larimer F.W., Olson M.V., Leigh J.A.
J. Bacteriol. 186:6956-6969(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: S2 / LL.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX950229 Genomic DNA. Translation: CAF29570.1.
RefSeqNP_987134.1. NC_005791.1.

3D structure databases

ProteinModelPortalQ6M1A3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING267377.MMP0014.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAF29570; CAF29570; MMP0014.
GeneID2762446.
KEGGmmp:MMP0014.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0585.
HOGENOMHOG000254431.
KOK06176.
OMAYCGLKDR.

Enzyme and pathway databases

BioCycMMAR267377:GJ77-20-MONOMER.

Family and domain databases

InterProIPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view]
PANTHERPTHR13326. PTHR13326. 1 hit.
PfamPF01142. TruD. 1 hit.
[Graphical view]
SUPFAMSSF55120. SSF55120. 2 hits.
TIGRFAMsTIGR00094. tRNA_TruD_broad. 1 hit.
PROSITEPS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRUD1_METMP
AccessionPrimary (citable) accession number: Q6M1A3
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: July 5, 2004
Last modified: May 14, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families