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Q6M1A3

- TRUD1_METMP

UniProt

Q6M1A3 - TRUD1_METMP

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Protein

Probable tRNA pseudouridine synthase D 1

Gene

truD1

Organism
Methanococcus maripaludis (strain S2 / LL)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.By similarity

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei63 – 631NucleophileBy similarity

GO - Molecular functioni

  1. pseudouridine synthase activity Source: InterPro
  2. RNA binding Source: InterPro

GO - Biological processi

  1. pseudouridine synthesis Source: InterPro
  2. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciMMAR267377:GJ77-20-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tRNA pseudouridine synthase D 1 (EC:5.4.99.27)
Alternative name(s):
tRNA pseudouridine(13) synthase
tRNA pseudouridylate synthase D 1
tRNA-uridine isomerase D 1
Gene namesi
Name:truD1
Ordered Locus Names:MMP0014
OrganismiMethanococcus maripaludis (strain S2 / LL)
Taxonomic identifieri267377 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
ProteomesiUP000000590: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 389389Probable tRNA pseudouridine synthase D 1PRO_0000152544Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi267377.MMP0014.

Structurei

3D structure databases

ProteinModelPortaliQ6M1A3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini135 – 345211TRUDPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.Curated
Contains 1 TRUD domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0585.
HOGENOMiHOG000254431.
KOiK06176.
OMAiYCGLKDR.

Family and domain databases

InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view]
PANTHERiPTHR13326. PTHR13326. 1 hit.
PfamiPF01142. TruD. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 2 hits.
TIGRFAMsiTIGR00094. tRNA_TruD_broad. 1 hit.
PROSITEiPS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6M1A3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKFRQKHEDF IVNEILEYEL NDYGNYFLYK LQKNGIENLK AISYLSKNFE
60 70 80 90 100
VPTKEIGYCG LKDRHAITTQ YVSIPKEYGK LSLDEDNLKL EYVGTIEKPL
110 120 130 140 150
KIGRLYGNRF EIIARAVDKD EFLKIADNIR NLSSGAPNYY DDQRFGSVFN
160 170 180 190 200
GKFIAKEILK GNYEEVVKIL LTSYTKSEKK QLKDLKRFIA KNWGNWDECL
210 220 230 240 250
EYIDKKQIRS KMFRNMVKSL TYENDFKKAF KYVDNRLKEL FISAYQSYLW
260 270 280 290 300
NECLKEFLKE VIPKENRIYV DYSCGTFLFY ENIEEELFDK LKEMDFPTIV
310 320 330 340 350
SDVEYTDPEK RIIKAILKKE RIKISDFEKL DFGKLKYTKR PIISIPEDVN
360 370 380
TGKFKSDELN SKKYKIDLEF SLKKGSYATI ILKRVFNIL
Length:389
Mass (Da):46,201
Last modified:July 5, 2004 - v1
Checksum:i15F89137BFB03189
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX950229 Genomic DNA. Translation: CAF29570.1.
RefSeqiNP_987134.1. NC_005791.1.
WP_011169958.1. NC_005791.1.

Genome annotation databases

EnsemblBacteriaiCAF29570; CAF29570; MMP0014.
GeneIDi2762446.
KEGGimmp:MMP0014.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX950229 Genomic DNA. Translation: CAF29570.1 .
RefSeqi NP_987134.1. NC_005791.1.
WP_011169958.1. NC_005791.1.

3D structure databases

ProteinModelPortali Q6M1A3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 267377.MMP0014.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAF29570 ; CAF29570 ; MMP0014 .
GeneIDi 2762446.
KEGGi mmp:MMP0014.

Phylogenomic databases

eggNOGi COG0585.
HOGENOMi HOG000254431.
KOi K06176.
OMAi YCGLKDR.

Enzyme and pathway databases

BioCyci MMAR267377:GJ77-20-MONOMER.

Family and domain databases

InterProi IPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view ]
PANTHERi PTHR13326. PTHR13326. 1 hit.
Pfami PF01142. TruD. 1 hit.
[Graphical view ]
SUPFAMi SSF55120. SSF55120. 2 hits.
TIGRFAMsi TIGR00094. tRNA_TruD_broad. 1 hit.
PROSITEi PS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S2 / LL.

Entry informationi

Entry nameiTRUD1_METMP
AccessioniPrimary (citable) accession number: Q6M1A3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: July 5, 2004
Last modified: October 1, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3