Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable tRNA pseudouridine synthase D 1

Gene

truD1

Organism
Methanococcus maripaludis (strain S2 / LL)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.By similarity

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei63 – 631NucleophileBy similarity

GO - Molecular functioni

  1. pseudouridine synthase activity Source: InterPro
  2. RNA binding Source: InterPro

GO - Biological processi

  1. pseudouridine synthesis Source: InterPro
  2. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciMMAR267377:GJ77-20-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tRNA pseudouridine synthase D 1 (EC:5.4.99.27)
Alternative name(s):
tRNA pseudouridine(13) synthase
tRNA pseudouridylate synthase D 1
tRNA-uridine isomerase D 1
Gene namesi
Name:truD1
Ordered Locus Names:MMP0014
OrganismiMethanococcus maripaludis (strain S2 / LL)
Taxonomic identifieri267377 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
ProteomesiUP000000590: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 389389Probable tRNA pseudouridine synthase D 1PRO_0000152544Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi267377.MMP0014.

Structurei

3D structure databases

ProteinModelPortaliQ6M1A3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini135 – 345211TRUDPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.Curated
Contains 1 TRUD domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0585.
HOGENOMiHOG000254431.
KOiK06176.
OMAiIGYCGLK.

Family and domain databases

InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view]
PANTHERiPTHR13326. PTHR13326. 1 hit.
PfamiPF01142. TruD. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 2 hits.
TIGRFAMsiTIGR00094. tRNA_TruD_broad. 1 hit.
PROSITEiPS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6M1A3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFRQKHEDF IVNEILEYEL NDYGNYFLYK LQKNGIENLK AISYLSKNFE
60 70 80 90 100
VPTKEIGYCG LKDRHAITTQ YVSIPKEYGK LSLDEDNLKL EYVGTIEKPL
110 120 130 140 150
KIGRLYGNRF EIIARAVDKD EFLKIADNIR NLSSGAPNYY DDQRFGSVFN
160 170 180 190 200
GKFIAKEILK GNYEEVVKIL LTSYTKSEKK QLKDLKRFIA KNWGNWDECL
210 220 230 240 250
EYIDKKQIRS KMFRNMVKSL TYENDFKKAF KYVDNRLKEL FISAYQSYLW
260 270 280 290 300
NECLKEFLKE VIPKENRIYV DYSCGTFLFY ENIEEELFDK LKEMDFPTIV
310 320 330 340 350
SDVEYTDPEK RIIKAILKKE RIKISDFEKL DFGKLKYTKR PIISIPEDVN
360 370 380
TGKFKSDELN SKKYKIDLEF SLKKGSYATI ILKRVFNIL
Length:389
Mass (Da):46,201
Last modified:July 5, 2004 - v1
Checksum:i15F89137BFB03189
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950229 Genomic DNA. Translation: CAF29570.1.
RefSeqiNP_987134.1. NC_005791.1.
WP_011169958.1. NC_005791.1.

Genome annotation databases

EnsemblBacteriaiCAF29570; CAF29570; MMP0014.
GeneIDi2762446.
KEGGimmp:MMP0014.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950229 Genomic DNA. Translation: CAF29570.1.
RefSeqiNP_987134.1. NC_005791.1.
WP_011169958.1. NC_005791.1.

3D structure databases

ProteinModelPortaliQ6M1A3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi267377.MMP0014.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAF29570; CAF29570; MMP0014.
GeneIDi2762446.
KEGGimmp:MMP0014.

Phylogenomic databases

eggNOGiCOG0585.
HOGENOMiHOG000254431.
KOiK06176.
OMAiIGYCGLK.

Enzyme and pathway databases

BioCyciMMAR267377:GJ77-20-MONOMER.

Family and domain databases

InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR001656. PsdUridine_synth_TruD.
IPR020119. PsdUridine_synth_TruD_CS.
IPR011760. PsdUridine_synth_TruD_insert.
[Graphical view]
PANTHERiPTHR13326. PTHR13326. 1 hit.
PfamiPF01142. TruD. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 2 hits.
TIGRFAMsiTIGR00094. tRNA_TruD_broad. 1 hit.
PROSITEiPS50984. TRUD. 1 hit.
PS01268. UPF0024. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S2 / LL.

Entry informationi

Entry nameiTRUD1_METMP
AccessioniPrimary (citable) accession number: Q6M1A3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: July 5, 2004
Last modified: February 4, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.