ID   Q6M058_METMP            Unreviewed;       731 AA.
AC   Q6M058;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 106.
DE   RecName: Full=Methyl-accepting chemotaxis protein {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=MMP0413 {ECO:0000313|EMBL:CAF29969.1};
OS   Methanococcus maripaludis (strain S2 / LL).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanococcaceae; Methanococcus.
OX   NCBI_TaxID=267377 {ECO:0000313|Proteomes:UP000000590};
RN   [1] {ECO:0000313|EMBL:CAF29969.1, ECO:0000313|Proteomes:UP000000590}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S2 / LL {ECO:0000313|Proteomes:UP000000590};
RX   PubMed=15466049; DOI=10.1128/JB.186.20.6956-6969.2004;
RA   Hendrickson E.L., Kaul R., Zhou Y., Bovee D., Chapman P., Chung J.,
RA   Conway de Macario E., Dodsworth J.A., Gillett W., Graham D.E., Hackett M.,
RA   Haydock A.K., Kang A., Land M.L., Levy R., Lie T.J., Major T.A.,
RA   Moore B.C., Porat I., Palmeiri A., Rouse G., Saenphimmachak C., Soll D.,
RA   Van Dien S., Wang T., Whitman W.B., Xia Q., Zhang Y., Larimer F.W.,
RA   Olson M.V., Leigh J.A.;
RT   "Complete genome sequence of the genetically tractable hydrogenotrophic
RT   methanogen Methanococcus maripaludis.";
RL   J. Bacteriol. 186:6956-6969(2004).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; BX950229; CAF29969.1; -; Genomic_DNA.
DR   RefSeq; WP_011170357.1; NC_005791.1.
DR   AlphaFoldDB; Q6M058; -.
DR   STRING; 267377.MMP0413; -.
DR   EnsemblBacteria; CAF29969; CAF29969; MMP0413.
DR   GeneID; 2761639; -.
DR   KEGG; mmp:MMP0413; -.
DR   PATRIC; fig|267377.15.peg.417; -.
DR   eggNOG; arCOG02320; Archaea.
DR   HOGENOM; CLU_000445_107_19_2; -.
DR   OrthoDB; 8523at2157; -.
DR   Proteomes; UP000000590; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR033463; sCache_3.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   InterPro; IPR000727; T_SNARE_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   Pfam; PF17202; sCache_3_3; 1.
DR   SMART; SM00304; HAMP; 2.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50192; T_SNARE; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Methylation {ECO:0000256|ARBA:ARBA00022481};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000590};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          316..368
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          444..680
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   DOMAIN          634..679
FT                   /note="T-SNARE coiled-coil homology"
FT                   /evidence="ECO:0000259|PROSITE:PS50192"
FT   REGION          690..709
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          406..437
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   731 AA;  78811 MW;  F0B7C487E0097CBC CRC64;
     MKLGTKKIGT KLLIFSIITV IIPIAILGIV SNNTITQDMK EQSADKLESS NEMANTIMDS
     RFTELCTLAE YASYTQGVKT SIKTGNVDDL ELRAETLKSA SNADLVIFTG NGGSTIASSS
     GEGITLDSTI LKVSKSSEKS GFEKIPEQTA LKFSDADVTG TDSALSIVVA YPIYDDAGTL
     GYVAFIDVLN NDHTLVDSIK ASTGDESTLF LENYRISTSV VSGNSRAVGT TASDVVYNTV
     VKENTEFMGS ANVVGQSFLT KYVPLKDSNG ATIGMVFVGT PEAQFTQLVN NARNNTIIIA
     LFGLLIAVVI SLVSSRSITK PINQLEDGVH KFGSGDYDHT INVKTGDELE ELANSFNKMA
     KDIKELHSML DADKLSLAKT LKEIFDIMDH LAEGDFSVRA DENRHKNKLQ KTINHAIENV
     SKMMENLKSE ITVLSDELED VGEGLKRAKE TSEQVTDAAN QVATAAADQS AKLQDTSDEL
     EKTAKAADMV YNDAEQSVDS AIEVKDNSET GVKKVENAID TMQKITNVID ELGKSIQELG
     EESKKINEVT VLIKDVAEQT GLLALNASIE AARAGDAGKG FAVVASEIKS LAEEIKKSVE
     DINRTINGIN KKVETTIDLG LAGRDEVDRG VVAIDEVNSA FMKIKESVET SAKMIAQIKD
     NAKNASNNTQ EALRNVQDIA SISEEFAATA EELTASSEEQ NRAVEEIDAS AEKMMEISRK
     LAEDADEFKT K
//