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Protein

D-aminoacyl-tRNA deacylase

Gene

dtdA

Organism
Methanococcus maripaludis (strain S2 / LL)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.UniRule annotation

Catalytic activityi

A D-aminoacyl-tRNA + H2O = a D-amino acid + tRNA.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 2 Zn2+ ions per subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
D-aminoacyl-tRNA deacylaseUniRule annotation (EC:3.1.1.96UniRule annotation)
Alternative name(s):
D-tyrosyl-tRNA(Tyr) deacylase
Gene namesi
Name:dtdAUniRule annotation
Ordered Locus Names:MMP0990
OrganismiMethanococcus maripaludis (strain S2 / LL)
Taxonomic identifieri267377 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
Proteomesi
  • UP000000590 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003452171 – 254D-aminoacyl-tRNA deacylaseAdd BLAST254

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi267377.MMP0990.

Structurei

3D structure databases

ProteinModelPortaliQ6LYK1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DtdA deacylase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01616. Archaea.
COG1650. LUCA.
HOGENOMiHOG000015484.
KOiK09716.
OMAiGHYSPKF.

Family and domain databases

HAMAPiMF_00562. Deacylase_DtdA. 1 hit.
InterProiIPR018033. Deacylase_DtdA_archaea.
IPR007508. DtdA.
[Graphical view]
PfamiPF04414. tRNA_deacylase. 1 hit.
[Graphical view]
PIRSFiPIRSF016210. UCP016210. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6LYK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDYLLISSET DPASQNLKKH VENYGYSVFN IEKKSTQTNY SEFPQSEMYI
60 70 80 90 100
FLSKHASESK KPTLTVHTPG NLTDDNSHGG NPEEISPCNP VFNTLMLQNM
110 120 130 140 150
NKYNEMEEYK ELGFDVSFEV LHHGPTDLKA PSAFVEIGSS EEQWQIDDAA
160 170 180 190 200
EIITNSLIDT LNSIQNSEYD EKEKIIGIGG GHYSPKFTKL ALREEYYVGY
210 220 230 240 250
LTPKHAKLSE NILNQLTSKQ EFDFIGIDWK GLYGEDKRKY VEFFDENDIS

WQRV
Length:254
Mass (Da):29,152
Last modified:July 5, 2004 - v1
Checksum:iAB08993D89724A34
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950229 Genomic DNA. Translation: CAF30546.1.
RefSeqiWP_011170934.1. NC_005791.1.

Genome annotation databases

EnsemblBacteriaiCAF30546; CAF30546; MMP0990.
GeneIDi2761585.
KEGGimmp:MMP0990.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950229 Genomic DNA. Translation: CAF30546.1.
RefSeqiWP_011170934.1. NC_005791.1.

3D structure databases

ProteinModelPortaliQ6LYK1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi267377.MMP0990.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAF30546; CAF30546; MMP0990.
GeneIDi2761585.
KEGGimmp:MMP0990.

Phylogenomic databases

eggNOGiarCOG01616. Archaea.
COG1650. LUCA.
HOGENOMiHOG000015484.
KOiK09716.
OMAiGHYSPKF.

Family and domain databases

HAMAPiMF_00562. Deacylase_DtdA. 1 hit.
InterProiIPR018033. Deacylase_DtdA_archaea.
IPR007508. DtdA.
[Graphical view]
PfamiPF04414. tRNA_deacylase. 1 hit.
[Graphical view]
PIRSFiPIRSF016210. UCP016210. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiDTDA_METMP
AccessioniPrimary (citable) accession number: Q6LYK1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.