Q6LY04 (RPIA_METMP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose-5-phosphate isomerase A
EC=5.3.1.6

Alternative name(s):
Phosphoriboisomerase A
Short name=PRI

Gene names

Name:	rpiA
Ordered Locus Names:	MMP1189

Organism

Methanococcus maripaludis (strain S2 / LL) [Complete proteome] [HAMAP]

Taxonomic identifier

267377 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length	239 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: InterPro
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 239	239	Ribose-5-phosphate isomerase A HAMAP MF_00170		PRO_0000158512

Sequences

	Sequence		Length	Mass (Da)
	Q6LY04 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: C1C40E851DF21457	FASTA	239	25,658
	10 20 30 40 50 60 MARTKKANDE VATDSDSLKL KVAKQAAKLV KDEMVVGLGS GSTANLFIQE LGKRVVEEEL 70 80 90 100 110 120 YIYGVPTSFD SRMMASNSGI PLISLDQCGE IDIAIDGADE VCKKTLSLIK GGGGCHTMEK 130 140 150 160 170 180 IVDYHAKEFV VLADEGKLVE SLGDKTAVPL EVIPFAYSTV LNKLLDMNTA PAIRSGSGKM 190 200 210 220 230 GPVITDNGNM IIDVFINIED AEETETMLNN IPGVLENGIF SKCDKVLVGT SKKVEILKK

References

[1]

"Complete genome sequence of the genetically tractable hydrogenotrophic methanogen Methanococcus maripaludis." Hendrickson E.L., Kaul R., Zhou Y., Bovee D., Chapman P., Chung J., Conway de Macario E., Dodsworth J.A., Gillett W., Graham D.E., Hackett M., Haydock A.K., Kang A., Land M.L., Levy R., Lie T.J., Major T.A., Moore B.C. , Porat I., Palmeiri A., Rouse G., Saenphimmachak C., Soell D., Van Dien S., Wang T., Whitman W.B., Xia Q., Zhang Y., Larimer F.W., Olson M.V., Leigh J.A. J. Bacteriol. 186:6956-6969(2004) [PubMed: 15466049] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S2 / LL.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX950229 Genomic DNA. Translation: CAF30745.1.
RefSeq	NP_988309.1. NC_005791.1.
3D structure databases
ProteinModelPortal	Q6LY04.
SMR	Q6LY04. Positions 15-239.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2761333.
GenomeReviews	Gene locus MMP1189 in contig BX950229_GR.
KEGG	mmp:MMP1189.
NMPDR	fig|267377.1.peg.1189.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG515603.
OMA	GGDPEYR.
ProtClustDB	PRK00702.
Enzyme and pathway databases
BioCyc	MMAR267377:MMP1189-MONOMER.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A. [Tree]
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. IPR014036. Tscrpt_reg_HTH_DeoR. [Graphical view]
KO	K01807.
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF00455. DeoR. 1 hit. PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. RpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_METMP

Accession

Primary (citable) accession number: Q6LY04

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 7, 2005
Last sequence update:	July 5, 2004
Last modified:	November 16, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program